Results 71 to 80 of about 35,408 (198)

Unlocking the Gates: A Novel Diagnostic Molecule for Quantifying Efflux Levels in Gram‐Positive Bacteria

open access: yesAdvanced Healthcare Materials, EarlyView.
Efflux‐mediated resistance compromises antibiotic efficacy, yet rapid detection remains elusive. This study presents a novel phenazinium‐based diagnostic molecule for quantifying bacterial efflux levels in Gram‐positive pathogens. The optimized compound enables precise, real‐time efflux assessment using fluorescence and colorimetric techniques ...
Mrunal Patil   +15 more
wiley   +1 more source

Summary Statement on Cardiopulmonary Exercise Testing in Chronic Heart Failure due to Left Ventricular Dysfunction Recommendations for Performance and Interpretation

open access: yesMonaldi Archives for Chest Disease, 2016
Cardiopulmonary exercise testing (CPET) is a non-invasive tool that provides the physician with relevant information to assess the integrated response to exercise involving pulmonary, cardiovascular, haematopoietic, neuro-psychological, and skeletal ...
Ugo Corrà, Massimo F. Piepoli
doaj   +1 more source

Mimicking the Dystrophic Cardiac Extracellular Environment through DystroGel

open access: yesAdvanced Healthcare Materials, EarlyView.
This research introduces DystroGel, a cutting‐edge biocompatible pathological hydrogel derived from decellularized dystrophic porcine heart tissue, suitable for tissue modeling applications. Rheological and proteomic analyses reveal structural and protein composition modifications, underscoring its unique properties.
Maila Chirivì   +19 more
wiley   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

open access: yesAdvanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto   +2 more
wiley   +1 more source

Inorganic Nanomaterials Meet the Immune System: An Intricate Balance

open access: yesAdvanced Healthcare Materials, EarlyView.
Metal nanomaterials influence the immune responses, such as cytokine production and T‐cell activity. Unintended immune modulation can have significant consequences while its fine‐tuning may transform the oncology care. Within this review, a critical analysis is offered regarding the nano/immune‐interaction and suggests the future research directions to
Gloria Pizzoli   +3 more
wiley   +1 more source

Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics

open access: yesAdvanced Healthcare Materials, EarlyView.
This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold   +2 more
wiley   +1 more source

Nemaline Myopathy: Respiratory Failure

open access: yesPediatric Neurology Briefs, 1991
A Japanese boy with nemaline myopathy diagnosed at three years of age and complicated by severe respiratory failure at 8 years is reported from the Division of Child Neurology, National Center Hospital for Mental, Nervous, and Muscular Disorders, Kodaira,
J Gordon Millichap
doaj   +1 more source

Hydrogel‐Impregnated Robust Interlocking Nano Connector (HiRINC) for Noninvasive Anti‐Migration of Esophageal Stent

open access: yesAdvanced Materials, EarlyView.
The development of hydrogel‐impregnated robust interlocking nano connector (HiRINC) aims to address stent migration by improving tissue adhesion and reducing mechanical mismatch in self‐expandable metallic stents (SEMSs). The network‐like porous layer of HiRINC enhances adhesion and energy dissipation, demonstrates through ex vivo and in vivo tests ...
Eunyoung Jeon   +8 more
wiley   +1 more source

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