Results 121 to 130 of about 16,243 (160)

Identification, validation, and characterization of approved and investigational drugs interfering with the SARS‐CoV‐2 endoribonuclease Nsp15

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Since the emergence of SARS‐CoV‐2 at the end of 2019, the virus has caused significant global health and economic disruptions. Despite the rapid development of antiviral vaccines and some approved treatments such as remdesivir and paxlovid, effective antiviral pharmacological treatments for COVID‐19 patients remain limited. This study explores
Spyros D. Chatziefthymiou, Maria Kuzikov, Sara Afandi, Greta Kovacs, Sukrit Srivastava, Andrea Zaliani, Andrey Gruzinov, Guillaume Pompidor, Michele Lunelli, Golam Rizvee Ahmed, Jörg Labahn, Johanna Hakanpää, Björn Windshügel, Michael Kolbe   +13 more
wiley   +1 more source

Supporting Pediatric RSV Clinical Trials Through Close Epidemiological Surveillance During the SARS‐CoV‐2 Pandemic

Pharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
ABSTRACT Clesrovimab, an extended half‐life monoclonal antibody, aims to protect infants for an entire RSV season. The pandemic impacted RSV epidemiology and strategies were implemented to support clesrovimab trials. Near real‐time monitoring of data showed minimal RSV activity in 2020.
Rennie Joshi, Georges J. Nahhas, Carmen S. Arriola, Patricia Saddier, Andrea Guerra   +4 more
wiley   +1 more source

Development of Dual ‘RT‐LAMP‐LFA’ Rapid Detection Technology With Gold Magnetic Nanoparticles for Influenza Virus

Microbial Biotechnology, Volume 18, Issue 6, June 2025.
This study develops a dual ‘RT‐LAMP‐LFA’ detection technology with GoldMag for influenza virus. ABSTRACT Seasonal and persistent outbreaks of influenza viruses represent a significant challenge to global public health. Rapid, convenient and accurate diagnosis methods of influenza viruses are crucial for timely treatment to mitigate morbidity and ...
Haiyang Fan, Yonglong Gong, Mengying Chang, Juan Gao, Mengjia Li, Siyu Chen, Ruoyi Yang, Muxue Zhao, Yali Cui, Wenli Hui   +9 more
wiley   +1 more source

Inhibitory effects of antiviral compounds on respiratory syncytial virus replication in vitro

, 1987
Fuyuhiko Kawana, Shirô Shigeta, Mitsuaki Hosoya, Hitoshi Suzuki, Erik De Clercq   +4 more
openalex   +1 more source

An individualised mobile app was beneficial for the mothers of infants with severe congenital heart defects

Acta Paediatrica, Volume 114, Issue 6, Page 1238-1248, June 2025.
Abstract Aim This national study focused on the individualised Heart Observation (HOBS) mobile phone app, which helps the parents of infants with severe congenital heart disease (CHD) with discharge preparations and decision making at home. Methods We enrolled two groups of parents from 2021 to 2023, during their child's initial hospitalisation at Oslo
Elin Hjorth‐Johansen, Elin Børøsund, Anne Moen, Ingeborg Martinsen Østen, Gunnar Wik, Anne Lee Solevåg, Siw Helen Westby Eger, Henrik Holmstrøm   +7 more
wiley   +1 more source

Serum immunoglobulin G antibody subclass response to respiratory syncytial virus F and G glycoproteins after first, second, and third infections

, 1989
David K. Wagner, P. M. Muelenaer, Fred Henderson, M H Snyder, Charles B. Reimer, Edward E. Walsh, Larry J. Anderson, David L. Nelson, Brian R. Murphy   +8 more
openalex   +1 more source

The severity of the first occurrence of bronchiolitis increased the risk of developing asthma symptoms

Acta Paediatrica, Volume 114, Issue 6, Page 1283-1290, June 2025.
Abstract Aim The relationship between bronchiolitis and asthma is complex. We assessed whether patients admitted to a paediatric intensive care unit (PICU) with bronchiolitis had a greater risk of developing asthma than patients admitted to a paediatric ward.
Cedric Agossah, Julien Marie, Yasmine Bendoukha, Cecile Vallet, Jacques Brouard, David Brossier   +5 more
wiley   +1 more source

High‐flow nasal cannula oxygen therapy for children with bronchiolitis: Implementation of a national guideline

Acta Paediatrica, Volume 114, Issue 6, Page 1291-1297, June 2025.
Abstract Aim High flow nasal cannula (HFNC) therapy is a form of respiratory support used in children with bronchiolitis. A national guideline for the use of HFNC was published in The Netherlands in 2020. We studied the implementation and use of this guideline.
Nike Beckeringh, Rosalie S. N. Linssen, Berber Kapitein, Job B. M. van Woensel, Frans B. Plötz, Pediatric Research and Evaluation Network (PREN) Amsterdam study group, M. Bijlsma, M. Felderhof, J. Hol, M. van Houten, A. van Kempen, F. Nauta, N. Oeij, N. Ran, M. Rijpert, G.W. ten Tusscher   +15 more
wiley   +1 more source

Strain Variation of Respiratory Syncytial Virus

, 1987
L. Morgan, E. G. Routledge, M. M. Willcocks, A. C. R. Samson, R. Scott, G. L. Toms   +5 more
openalex   +1 more source

Anti‐PF4 mediated thrombocytopenia and thrombosis associated with acute cytomegalovirus infection displays both HIT‐like and VITT‐like characteristics

British Journal of Haematology, Volume 206, Issue 6, Page 1737-1742, June 2025.
Summary Vaccine‐induced immune thrombocytopenia and thrombosis (VITT) is one of several anti‐platelet factor 4 (anti‐PF4)‐associated immune thrombocytopenia and thrombosis (PITT) syndromes. As well as following adenoviral vector vaccines, VITT has recently been described following acute adenovirus infection.
Phillip L. R. Nicolson, Samantha J. Montague, Richard J. Buka, Anthony Calvert, Jo‐Ann I. Sheppard, Yi Zhang, Jing Jing Wang, Jack Sharman, Eman Hassan, James Harrison, Errin Lawrence, Phillip El‐Dalil, Dhruv Parekh, Husam Osman, Tom P. Gordon, Ishac Nazy, Theodore E. Warkentin, Will A. Lester   +17 more
wiley   +1 more source