Results 11 to 20 of about 11,366 (143)

Identification and Genetic Characterization of a Novel Respirovirus in Alpine Chamois (Rupicapra rupicapra rupicapra) [PDF]

Animals, 2020
The Respirovirus genus, family Paramamixoviridae, includes respiratory viral pathogens. Here we report the identification and genetic characterization of a respirovirus in an Alpine chamois showing interstitial pneumonia associated with catarrhal ...
Camilla Luzzago, Erika Ebranati, Antonio Lavazza, Martina Besozzi, Gianguglielmo Zehender, Paolo Lanfranchi, Stefania Lauzi   +6 more
doaj   +5 more sources

Porcine Respirovirus 1 Suppresses Host Type I Interferon Production and the JAK-STAT Signaling Pathway

Viruses, 2023
Porcine respirovirus 1 (PRV1), first reported in Hong Kong, is currently widely spread in several countries. Our knowledge of the clinical significance and the pathogenicity of this virus is still limited.
Yanhua Li, Chenxi Li
doaj   +4 more sources

Structural basis for potent neutralization of human respirovirus type 3 by protective single-domain camelid antibodies

Nature Communications
Respirovirus 3 is a leading cause of severe acute respiratory infections in vulnerable human populations. Entry into host cells is facilitated by the attachment glycoprotein and the fusion glycoprotein (F).
Nicole V. Johnson, Revina C. van Scherpenzeel, Mark J. G. Bakkers, Ajit R. Ramamohan, Daan van Overveld, Lam Le, Johannes P. M. Langedijk, Joost A. Kolkman, Jason S. McLellan   +8 more
doaj   +4 more sources

A serosurvey for bovine respirovirus 3 in Turkish domestic ruminants: The first comparison study of A and C genotypes [PDF]

Veterinary Medicine and Science, 2021
Bovine parainfluenza virus‐3 (BPIV‐3), also known as bovine respirovirus 3, causes serious respiratory infection in ungulates, often involving other pathogens, such as viruses, bacteria and mycoplasmas. In this study, we evaluated antibody titers against
Bahadir Muftuoglu, Hanne Nur Kurucay, Ahmed Eisa Elhag, Serdar Yildirim, Yasemin Cicek‐Yildiz, Cuneyt Tamer, Emre Ozan, Kezban Can Sahna, Yakup Yildirim, Harun Albayrak, Semra Okur‐Gumusova, Zafer Yazici   +11 more
doaj   +5 more sources

Detection of Porcine Respirovirus 1 (PRV1) in Poland: Incidence of Co-Infections with Influenza A Virus (IAV) and Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) in Herds with a Respiratory Disease [PDF]

Viruses, 2022
Porcine respirovirus 1 (PRV1) is also known as porcine parainfluenza virus 1 (PPIV1). The prevalence and the role of PRV1 infections for pig health is largely unknown.
Aleksandra Woźniak, Piotr Cybulski, Lilla Denes, Gyula Balka, Tomasz Stadejek   +4 more
doaj   +4 more sources

Genetic diversity and evolutionary analysis of human respirovirus type 3 strains isolated in Kenya using complete hemagglutinin-neuraminidase (HN) gene.

PLoS ONE, 2020
Human respirovirus type 3 (HRV3) is a leading etiology of lower respiratory tract infections in young children and ranks only second to the human respiratory syncytial virus (HRSV).
Juliet Elusah, Wallace Dimbuson Bulimo, Silvanos Mukunzi Opanda, Samwel Lifumo Symekher, Fred Wamunyokoli   +4 more
doaj   +5 more sources

First detection of porcine respirovirus 1 in Germany and the Netherlands [PDF]

Transboundary and Emerging Diseases, 2020
PRV1 was first detected in deceased pigs from Hong Kong in 2013. It has since been detected in the USA, Chile and most recently in Hungary. Information on the pathogenicity and global spread is sparse, however it has been speculated to play a role in the porcine respiratory disease complex. In an effort to investigate the porcine virome, we screened 53
Schuele, Leonard, Lizarazo‐Forero, Erley, Cassidy, Hayley, Strutzberg‐Minder, Katrin, Boehmer, Jan, Schuetze, Sabine, Loebert, Sandra, Lambrecht, Claudia, Harlizius, Juergen, Friedrich, Alex W., Peter, Silke, Rossen, John W. A., Couto, Natacha   +12 more
openaire   +5 more sources

Divergent Viruses Discovered in Swine Alter the Understanding of Evolutionary History and Genetic Diversity of the Respirovirus Genus and Related Porcine Parainfluenza Viruses

Microbiology Spectrum, 2022
Paramyxoviridae is a rapidly growing family of viruses, whose potential for cross-species transmission makes it difficult to predict the harm of newly emerging viruses to humans and animals. To better understand their diversity, evolutionary history, and
Jin Zhao, Jiumeng Sun, Xinxin Li, Gang Xing, Yifang Zhang, Alexander Lai, Guy Baele, Xiang Ji, Shuo Su   +8 more
doaj   +4 more sources

Differential regulation of type I interferon and epidermal growth factor pathways by a human Respirovirus virulence factor. [PDF]

PLoS Pathogens, 2009
A number of paramyxoviruses are responsible for acute respiratory infections in children, elderly and immuno-compromised individuals, resulting in airway inflammation and exacerbation of chronic diseases like asthma.
Grégory Caignard, Anastassia V Komarova, Mehdi Bouraï, Thomas Mourez, Yves Jacob, Louis M Jones, Flore Rozenberg, Astrid Vabret, François Freymuth, Frédéric Tangy, Pierre-Olivier Vidalain   +10 more
doaj   +6 more sources

Respirovirus C protein inhibits activation of type I interferon receptor‐associated kinases to block JAK‐STAT signaling [PDF]

FEBS Letters, 2019
Respirovirus C protein blocks the type I interferon (IFN)‐stimulated activation of the JAK‐STAT pathway. It has been reported that C protein inhibits IFN‐α‐stimulated tyrosine phosphorylation of STATs, but the underlying mechanism is poorly understood. Here, we show that the C protein of Sendai virus (SeV), a member of the Respirovirus genus, binds to ...
Yoshinori Kitagawa, Mayu Yamaguchi, Miki Kohno, Madoka Sakai, Masae Itoh, Bin Gotoh   +5 more
openaire   +5 more sources