Results 21 to 30 of about 10,943 (110)

Porcine Respirovirus 1 Suppresses Host Type I Interferon Production and the JAK-STAT Signaling Pathway

Viruses, 2023
Porcine respirovirus 1 (PRV1), first reported in Hong Kong, is currently widely spread in several countries. Our knowledge of the clinical significance and the pathogenicity of this virus is still limited.
Yanhua Li, Chenxi Li
doaj   +1 more source

Characterization of viral pathogens associated with symptomatic upper respiratory tract infection in adults during a low COVID-19 transmission period [PDF]

PeerJ, 2023
Background The epidemiology of respiratory tract infections (RTI) has dramatically changed over the course of the COVID-19 pandemic. A major effort in the clinical management of RTI has been directed toward diagnosing COVID-19, while the causes of other,
Nurlan Sandybayev, Vyacheslav Beloussov, Vitaliy Strochkov, Maxim Solomadin, Joanna Granica, Sergey Yegorov   +5 more
doaj   +2 more sources

The active lung microbiota landscape of COVID-19 patients through the metatranscriptome data analysis [PDF]

BioImpacts, 2022
Introduction: With the outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the interaction between the host and SARS-CoV-2 was widely studied. However, it is unclear whether and how SARS-
Yang Han, Zhilong Jia, Jinlong Shi, Weidong Wang, Kunlun He   +4 more
doaj   +1 more source

Detection of Porcine Respirovirus 1 (PRV1) in Poland: Incidence of Co-Infections with Influenza A Virus (IAV) and Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) in Herds with a Respiratory Disease

Viruses, 2022
Porcine respirovirus 1 (PRV1) is also known as porcine parainfluenza virus 1 (PPIV1). The prevalence and the role of PRV1 infections for pig health is largely unknown.
Aleksandra Woźniak, Piotr Cybulski, Lilla Denes, Gyula Balka, Tomasz Stadejek   +4 more
doaj   +1 more source

Isolation and Identification of a Genotype C Bovine Parainfluenza Virus Type 3 and Its Pathogenicity in Albino Guinea Pigs

Transboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023
Bovine parainfluenza virus type 3 (BPIV3) is a significant pathogen in cattle, causing a range of respiratory symptoms from mild to severe. In this study, we isolated a BPIV3 (BPIV3/SX/2021) strain using Madin‐Darby bovine kidney cells from a lung tissue sample obtained in Shaanxi province.
Yu Han, Fathalrhman Eisa Addoma Adam, Riteng Zhang, Yan Gao, Jianlin Lei, Kejia Lu, Xinglong Wang, Sa Xiao, Haijin Liu, Zengqi Yang, Lin-Zhu Ren   +10 more
wiley   +1 more source

Differential regulation of type I interferon and epidermal growth factor pathways by a human Respirovirus virulence factor. [PDF]

PLoS Pathogens, 2009
A number of paramyxoviruses are responsible for acute respiratory infections in children, elderly and immuno-compromised individuals, resulting in airway inflammation and exacerbation of chronic diseases like asthma.
Grégory Caignard, Anastassia V Komarova, Mehdi Bouraï, Thomas Mourez, Yves Jacob, Louis M Jones, Flore Rozenberg, Astrid Vabret, François Freymuth, Frédéric Tangy, Pierre-Olivier Vidalain   +10 more
doaj   +1 more source

Sendai F/HN pseudotyped lentiviral vector transduces human ciliated and non-ciliated airway cells using α 2,3 sialylated receptors

Molecular Therapy: Methods & Clinical Development, 2022
A lentiviral vector (LV) pseudotype derived from the fusion (F) and hemagglutinin-neuraminidase (HN) glycoproteins of a murine respirovirus (Sendai virus) facilitates efficient targeting of murine lung in vivo.
Rosie J. Munday, Tiziana Coradin, Rachael Nimmo, Yatish Lad, Stephen C. Hyde, Kyriacos Mitrophanos, Deborah R. Gill   +6 more
doaj   +1 more source

Human parainfluenza 2 & 4: Clinical and genetic epidemiology in the UK, 2013–2017, reveals distinct disease features and co‐circulating genomic subtypes

Influenza and Other Respiratory Viruses, Volume 16, Issue 6, Page 1122-1132, November 2022., 2022
Abstract Background Human Parainfluenza viruses (HPIV) comprise of four members of the genetically distinct genera of Respirovirus (HPIV1&3) and Orthorubulavirus (HPIV2&4), causing significant upper and lower respiratory tract infections worldwide, particularly in children.
Akhil Chellapuri, Matthew Smitheman, Joseph G. Chappell, Gemma Clark, Hannah C. Howson‐Wells, Louise Berry, Jonathan K. Ball, William L. Irving, Alexander W. Tarr, C. Patrick McClure   +9 more
wiley   +1 more source

European and American Strains of Porcine Parainfluenza Virus 1 (PPIV-1) Belong to Two Distinct Genetic Lineages

Pathogens, 2022
Porcine parainfluenza virus 1 (PPIV-1) is a recently emerged respirovirus closely related to human parainfluenza virus 1 (HPIV-1) and Sendai virus (SenV).
Tomasz Stadejek, Piotr Cybulski, Phillip C. Gauger, Aleksandra Woźniak   +3 more
doaj   +1 more source

Serological evidence of a pararubulavirus and a betacoronavirus in the geographically isolated Christmas Island flying‐fox (Pteropus natalis)

Transboundary and Emerging Diseases, Volume 69, Issue 5, Page e2366-e2377, September 2022., 2022
Abstract Due to their geographical isolation and small populations, insular bats may not be able to maintain acute immunizing viruses that rely on a large population for viral maintenance. Instead, endemic transmission may rely on viruses establishing persistent infections within hosts or inducing only short‐lived neutralizing immunity.
Laura A. Pulscher, Alison J. Peel, Karrie Rose, Justin A. Welbergen, Michelle L. Baker, Victoria Boyd, Samantha Low‐Choy, Dan Edson, Christopher Todd, Annabel Dorrestein, Jane Hall, Shawn Todd, Christopher C. Broder, Lianying Yan, Kai Xu, Grantley R. Peck, David N. Phalen   +16 more
wiley   +1 more source