Results 41 to 50 of about 10,943 (110)

Differential Induction and Signaling of Type I and III Interferons During Infection of Human Nasal Epithelial Cells With the Four Human Parainfluenza Virus Types

open access: yesJournal of Medical Virology, Volume 98, Issue 3, March 2026.
ABSTRACT Human parainfluenza viruses (HPIVs) commonly cause croup and lower respiratory tract infections in young children. Despite typically self‐limiting with mild symptoms, the innate immune responses to HPIVs remain poorly understood, especially across all four types in human nasal epithelial cells (hNECs), the primary infection site.
Hsiao Hui Ong   +6 more
wiley   +1 more source

Multicenter evaluation of the QIAstat Respiratory Panel-A new rapid highly multiplexed PCR based assay for diagnosis of acute respiratory tract infections.

open access: yesPLoS ONE, 2020
Acute respiratory tract infections (ARTI), including the common cold, pharyngitis, sinusitis, otitis media, bronchiolitis and pneumonia are the most common diagnoses among patients seeking medical care in western countries, and account for most ...
Marijo Parčina   +5 more
doaj   +1 more source

Detection of porcine parainfluenza virus type-1 antibody in swine serum using whole-virus ELISA, indirect fluorescence antibody and virus neutralizing assays

open access: yesBMC Veterinary Research, 2022
Background Porcine parainfluenza virus 1 (PPIV-1) is a respiratory virus in the family Paramyxoviridae and genus Respirovirus. It is closely related to bovine parainfluenza virus 3, human parainfluenza virus 1, and Sendai virus.
Michael Welch   +9 more
doaj   +1 more source

Characterization of Two Porcine Parainfluenza Virus 1 Isolates and Human Parainfluenza Virus 1 Infection in Weaned Nursery Pigs

open access: yesVeterinary Sciences, 2022
Porcine parainfluenza virus 1 (PPIV1) is a newly characterized porcine respiratory virus. Recent experimental challenge studies in three-week-old nursery pigs failed to cause disease.
Michael Welch   +7 more
doaj   +1 more source

Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li   +13 more
wiley   +1 more source

Structural basis for potent neutralization of human respirovirus type 3 by protective single-domain camelid antibodies

open access: yesNature Communications
Respirovirus 3 is a leading cause of severe acute respiratory infections in vulnerable human populations. Entry into host cells is facilitated by the attachment glycoprotein and the fusion glycoprotein (F).
Nicole V. Johnson   +8 more
doaj   +1 more source

Circular RNAs as Biomarkers and Therapeutic Targets in Diabetic Cardiovascular Complications

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
This graphic abstract elaborates on the recent mechanism of circular RNAs (circRNAs) in the pathogenesis, diagnosis and treatment of diabetic cardiovascular complications. Diabetes mellitus induces oxidative/inflammatory stress, followed by endothelial dysfunction and leads to micro‐/macro‐vascular complications.
Shreya Singh Beniwal   +10 more
wiley   +1 more source

Genetic diversity and evolutionary analysis of human respirovirus type 3 strains isolated in Kenya using complete hemagglutinin-neuraminidase (HN) gene.

open access: yesPLoS ONE, 2020
Human respirovirus type 3 (HRV3) is a leading etiology of lower respiratory tract infections in young children and ranks only second to the human respiratory syncytial virus (HRSV).
Juliet Elusah   +4 more
doaj   +1 more source

Thoracic Ultrasonography Findings and Their Association With Respiratory Pathogens in 221 Young Beef Cattle at Fattening Farms: A Cross‐Sectional Study

open access: yesJournal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background Thoracic ultrasonography (TUS) could improve antibiotic treatment selection in cattle with respiratory diseases. Hypothesis/Objectives Evaluate the association between respiratory pathogens and consolidations on TUS in feedlot cattle, at both individual and group levels. Animals A total of 221 bulls, aged 8.8 months and weighing 322.
Maud Rouault   +3 more
wiley   +1 more source

Clinical and Epidemiological Insights into a Parainfluenza Virus Type 3 Outbreak in Multiple Myeloma Patients

open access: yesJournal of Medical Virology, Volume 97, Issue 5, May 2025.
ABSTRACT Human parainfluenza virus type 3 (HPIV‐3) can be responsible for mild to severe respiratory infections and hospital epidemics. We investigated an outbreak in a hematology unit. Respiratory viruses were screened using multiplex PCR. HPIV‐3 quantification and whole‐genome sequencing were performed on HPIV‐3 positive respiratory samples. Clinical
Sarah Timsit   +13 more
wiley   +1 more source

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