Results 41 to 50 of about 11,514 (172)

Isolation and Identification of a Genotype C Bovine Parainfluenza Virus Type 3 and Its Pathogenicity in Albino Guinea Pigs

Transboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023
Bovine parainfluenza virus type 3 (BPIV3) is a significant pathogen in cattle, causing a range of respiratory symptoms from mild to severe. In this study, we isolated a BPIV3 (BPIV3/SX/2021) strain using Madin‐Darby bovine kidney cells from a lung tissue sample obtained in Shaanxi province.
Yu Han, Fathalrhman Eisa Addoma Adam, Riteng Zhang, Yan Gao, Jianlin Lei, Kejia Lu, Xinglong Wang, Sa Xiao, Haijin Liu, Zengqi Yang, Lin-Zhu Ren   +10 more
wiley   +1 more source

Human parainfluenza 2 & 4: Clinical and genetic epidemiology in the UK, 2013–2017, reveals distinct disease features and co‐circulating genomic subtypes

Influenza and Other Respiratory Viruses, Volume 16, Issue 6, Page 1122-1132, November 2022., 2022
Abstract Background Human Parainfluenza viruses (HPIV) comprise of four members of the genetically distinct genera of Respirovirus (HPIV1&3) and Orthorubulavirus (HPIV2&4), causing significant upper and lower respiratory tract infections worldwide, particularly in children.
Akhil Chellapuri, Matthew Smitheman, Joseph G. Chappell, Gemma Clark, Hannah C. Howson‐Wells, Louise Berry, Jonathan K. Ball, William L. Irving, Alexander W. Tarr, C. Patrick McClure   +9 more
wiley   +1 more source

Sendai F/HN pseudotyped lentiviral vector transduces human ciliated and non-ciliated airway cells using α 2,3 sialylated receptors

Molecular Therapy: Methods & Clinical Development, 2022
A lentiviral vector (LV) pseudotype derived from the fusion (F) and hemagglutinin-neuraminidase (HN) glycoproteins of a murine respirovirus (Sendai virus) facilitates efficient targeting of murine lung in vivo.
Rosie J. Munday, Tiziana Coradin, Rachael Nimmo, Yatish Lad, Stephen C. Hyde, Kyriacos Mitrophanos, Deborah R. Gill   +6 more
doaj   +1 more source

European and American Strains of Porcine Parainfluenza Virus 1 (PPIV-1) Belong to Two Distinct Genetic Lineages

Pathogens, 2022
Porcine parainfluenza virus 1 (PPIV-1) is a recently emerged respirovirus closely related to human parainfluenza virus 1 (HPIV-1) and Sendai virus (SenV).
Tomasz Stadejek, Piotr Cybulski, Phillip C. Gauger, Aleksandra Woźniak   +3 more
doaj   +1 more source

Analysis of Paramyxovirus Transcription and Replication by High-Throughput Sequencing. [PDF]

, 2019
We have developed a high-throughput sequencing (HTS) workflow for investigating paramyxovirus transcription and replication. We show that sequencing of oligo(dT)-selected polyadenylated mRNAs, without considering the orientation of the RNAs from which ...
Davison, AJ, Goodbourn, S, Hughes, DJ, Modha, S, Randall, RE, Vattipally, S, Wignall-Fleming, EB   +6 more
core   +4 more sources

Serological evidence of a pararubulavirus and a betacoronavirus in the geographically isolated Christmas Island flying‐fox (Pteropus natalis)

Transboundary and Emerging Diseases, Volume 69, Issue 5, Page e2366-e2377, September 2022., 2022
Abstract Due to their geographical isolation and small populations, insular bats may not be able to maintain acute immunizing viruses that rely on a large population for viral maintenance. Instead, endemic transmission may rely on viruses establishing persistent infections within hosts or inducing only short‐lived neutralizing immunity.
Laura A. Pulscher, Alison J. Peel, Karrie Rose, Justin A. Welbergen, Michelle L. Baker, Victoria Boyd, Samantha Low‐Choy, Dan Edson, Christopher Todd, Annabel Dorrestein, Jane Hall, Shawn Todd, Christopher C. Broder, Lianying Yan, Kai Xu, Grantley R. Peck, David N. Phalen   +16 more
wiley   +1 more source

Epidemiology and clinical manifestations of different enterovirus and rhinovirus types show that EV‐D68 may still have an impact on severity of respiratory infections

Journal of Medical Virology, Volume 94, Issue 8, Page 3829-3839, August 2022., 2022
Abstract Respiratory infections are often caused by enteroviruses (EVs). The aim of this study was to identify whether certain types of EV were more likely to cause severe illness in 2016, when an increasing spread of upper respiratory infections was observed in Gothenburg, Sweden.
Simon B. Larsson, Diana Vracar, Marie Karlsson, Johan Ringlander, Heléne Norder   +4 more
wiley   +1 more source

Human parainfluenza virus surveillance in pediatric patients with lower respiratory tract infections: a special view of parainfluenza type 4

Jornal de Pediatria (Versão em Português), 2018
Objective: Characterize the role of human parainfluenza virus and its clinical features in Brazilian children under 2 years of age presenting with acute lower respiratory tract infections.
Luciano M. Thomazelli, Danielle B.L. de Oliveira, Giuliana S. Durigon, Brett Whitaker, Shifaq Kamili, Eitan N. Berezin, Edison L. Durigon   +6 more
doaj   +3 more sources

Assessment of Viral Targeted Sequence Capture Using Nanopore Sequencing Directly from Clinical Samples [PDF]

, 2020
Shotgun metagenomic sequencing (SMg) enables the simultaneous detection and characterization of viruses in human, animal and environmental samples. However, lack of sensitivity still poses a challenge and may lead to poor detection and data acquisition ...
Cassidy, Hayley, Couto, Natacha, Friedrich, Alex W, Harlizius, Juergen, Lambrecht, Claudia, Lizarazo, Erley, Loebert, Sandra, Niesters, Hubert G M, Peter, Silke, Rossen, John W A, Schuele, Leonard, Schuetze, Sabine, Strutzberg-Minder, Katrin   +12 more
core   +1 more source

Application of shotgun metagenomics sequencing and targeted sequence capture to detect circulating porcine viruses in the Dutch–German border region

Transboundary and Emerging Diseases, Volume 69, Issue 4, Page 2306-2319, July 2022., 2022
Abstract Porcine viruses have been emerging in recent decades, threatening animal and human health, as well as economic stability for pig farmers worldwide. Next‐generation sequencing (NGS) can detect and characterize known and unknown viruses but has limited sensitivity when an unbiased approach, such as shotgun metagenomics sequencing, is used.
Leonard Schuele, Erley Lizarazo‐Forero, Katrin Strutzberg‐Minder, Sabine Schütze, Sandra Löbert, Claudia Lambrecht, Jürgen Harlizius, Alex W. Friedrich, Silke Peter, John W. A. Rossen, Natacha Couto   +10 more
wiley   +1 more source