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Distribution and Clinical Profile of Human Parainfluenza Viruses in Hospitalized Patients With Acute Febrile Illness. [PDF]

Int J Microbiol
Introduction Human parainfluenza viruses (HPIVs) are significant causes of respiratory infections, particularly in children, yet their epidemiology remains poorly understood in low‐ and middle‐income countries. HPIVs contribute to 20%–40% of pediatric lower respiratory tract infections (LRTIs) and are a leading cause of croup and hospitalizations. This
Devadiga S, Godbole NM, Varamballi P, Mukhopadhyay C, Jayaram A.   +4 more
europepmc   +2 more sources

Epidemiology and clinical manifestations of different enterovirus and rhinovirus types show that EV‐D68 may still have an impact on severity of respiratory infections

Journal of Medical Virology, Volume 94, Issue 8, Page 3829-3839, August 2022., 2022
Abstract Respiratory infections are often caused by enteroviruses (EVs). The aim of this study was to identify whether certain types of EV were more likely to cause severe illness in 2016, when an increasing spread of upper respiratory infections was observed in Gothenburg, Sweden.
Simon B. Larsson, Diana Vracar, Marie Karlsson, Johan Ringlander, Heléne Norder   +4 more
wiley   +1 more source

Human parainfluenza virus surveillance in pediatric patients with lower respiratory tract infections: a special view of parainfluenza type 4

Jornal de Pediatria (Versão em Português), 2018
Objective: Characterize the role of human parainfluenza virus and its clinical features in Brazilian children under 2 years of age presenting with acute lower respiratory tract infections.
Luciano M. Thomazelli, Danielle B.L. de Oliveira, Giuliana S. Durigon, Brett Whitaker, Shifaq Kamili, Eitan N. Berezin, Edison L. Durigon   +6 more
doaj   +3 more sources

Simultaneous outbreaks of respiratory disease in wild chimpanzees caused by distinct viruses of human origin

Emerging Microbes and Infections, 2019
Respiratory viruses of human origin infect wild apes across Africa, sometimes lethally. Here we report simultaneous outbreaks of two distinct human respiratory viruses, human metapneumovirus (MPV; Pneumoviridae: Metapneumovirus) and human respirovirus 3 (
Jacob D. Negrey, Rachna B. Reddy, Erik J. Scully, Sarah Phillips-Garcia, Leah A. Owens, Kevin E. Langergraber, John C. Mitani, Melissa Emery Thompson, Richard W. Wrangham, Martin N. Muller, Emily Otali, Zarin Machanda, David Hyeroba, Kristine A. Grindle, Tressa E. Pappas, Ann C. Palmenberg, James E. Gern, Tony L. Goldberg   +17 more
doaj   +1 more source

Intranasal vaccine against COVID-19 based on a recombinant variant of the Sendai virus (Paramyxoviridae: Respirovirus) strain Moscow

Вопросы вирусологии, 2023
Introduction. Intranasal vaccination using live vector vaccines based on non-pathogenic or slightly pathogenic viruses is the one of the most convenient, safe and effective ways to prevent respiratory infections, including COVID-19.
Gleb A. Kudrov, Sergei S. Zainutdinov, Antonina A. Grazhdantseva, Andrey V. Shipovalov, Galina F. Sivolobova, Anastasiya V. Semenova, Iuliia A. Merkuleva, Dmitry N. Shcherbakov, Oleg S. Taranov, Anna V. Zaykovskaya, Irina S. Shulgina, Oleg V. Pyankov, Galina V. Kochneva   +12 more
doaj   +1 more source

A serosurvey for bovine respirovirus 3 in Turkish domestic ruminants: The first comparison study of A and C genotypes

Veterinary Medicine and Science, 2021
Bovine parainfluenza virus‐3 (BPIV‐3), also known as bovine respirovirus 3, causes serious respiratory infection in ungulates, often involving other pathogens, such as viruses, bacteria and mycoplasmas. In this study, we evaluated antibody titers against
Bahadir Muftuoglu, Hanne Nur Kurucay, Ahmed Eisa Elhag, Serdar Yildirim, Yasemin Cicek‐Yildiz, Cuneyt Tamer, Emre Ozan, Kezban Can Sahna, Yakup Yildirim, Harun Albayrak, Semra Okur‐Gumusova, Zafer Yazici   +11 more
doaj   +1 more source

Prevalence Estimation and Genetic Characterization of Porcine Parainfluenza Virus 1 (PPIV-1) in Hungary and the First Report of the Virus in Slovakia. [PDF]

Transbound Emerg Dis
In the last few decades, many new paramyxoviruses have been discovered, causing diverse, mostly respiratory diseases in animals and humans. The porcine parainfluenza virus 1 (PPIV‐1, species Porcine respirovirus 1), which has been reported in many countries worldwide, was found in both healthy and clinically ill pigs showing respiratory signs. Here, we
Igriczi B, Dénes L, Czétényi A, Révész T, Somogyi Z, Balka G.   +5 more
europepmc   +2 more sources

Human parainfluenza virus 3 fusion protein cleavage: a key determinant of infection and spread

Journal of Virology
Human parainfluenza virus 3 (HPIV3) entry into target cells depends on a viral fusion complex composed of hemagglutinin-neuraminidase (HN) and fusion protein (F).
Kyle Stearns, Tara Marcink, Emily Pawlack, Elizabeth B. Sobolik, Matteo Porotto, Alexander L. Greninger, Stefan Nieweisk, Anne Moscona   +7 more
doaj   +1 more source

CircRNAs: Biogenesis, identification and expression analysis [PDF]

Cellular, Molecular and Biomedical Reports
Circular ribonucleic acids (CircRNAs) represent a category of noncoding RNAs characterized by a circular structure bonded through covalent bonds. Unlike linear RNAs, CircRNAs are not affected by exonucleases and exhibit more stable expression.
Esmaiel Azizzad Ranji, Danial Kahrizi, Masomeh Khanahmadi, Sajad Rashidi Monfared   +3 more
doaj   +1 more source

EMERGING VIRUSES ARE AN UNDERESTIMATED CAUSE OF UNDIAGNOSED FEBRILE ILLNESS IN UGANDA

International Journal of Infectious Diseases, 2023
Intro: Viruses that cause acute febrile illness (AFI) in sub-Saharan Africa (SSA) lead to a spectrum of clinical disease from mild to life-threatening. Viral infection is often undiagnosed, resulting in onward transmission of high consequence pathogens ...
S. Ashraf, H. Jerome, C. Davis, J. Shepherd, S. Vattipally, A. Filipe, P. Namuwulya, M. Mayanja, R. Downing, J. Salazar, H. Bukenya, M. Salazar, W. Witkowska, S. Atim, S. Balinandi, J. Lutwama, P. Kaleebu, J. Bwogi, E. Thomson   +18 more
doaj   +1 more source