Results 61 to 70 of about 10,606,337 (342)

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Biomechanical Analysis of Unplanned Gait Termination According to a Stop-Signal Task Performance: A Preliminary Study

open access: yesBrain Sciences, 2023
There is a correlation between cognitive inhibition and compensatory balance response; however, the correlation between response inhibition and gait termination is not clear. Objectives: The purpose of this study was to investigate the gait parameters of
Dong-Kyun Koo, Jung-Won Kwon
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Explicit and Implicit Devaluation Effects of Food-Specific Response Inhibition Training

open access: yesJournal of Cognition, 2023
The overvaluation of reward-associated stimuli such as energy-dense foods can drive compulsive eating behaviours, including overeating. Previous research has shown that training individuals to inhibit their responses towards appetitive stimuli can lead ...
Loukia Tzavella, Christopher D. Chambers
doaj   +1 more source

Spider stimuli improve response inhibition [PDF]

open access: yesConsciousness and Cognition, 2015
Anxiety can have positive effects on some aspects of cognition and negative effects on others. The current study investigated whether task-relevant anxiety could improve people's ability to withhold responses in a response inhibition task. Sixty-seven university students completed a modified and an unmodified version of the Sustained Attention to ...
Kyle M. Wilson   +2 more
openaire   +3 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Preliminary evidence of the impact of early childhood maltreatment and a preventive intervention on neural patterns of response inhibition in early adolescence.

open access: yesDevelopmental Science, 2017
Maltreated youths in foster care often experience negative developmental and psychological outcomes, which have been linked with poor response inhibition.
Kathryn F Jankowski   +5 more
semanticscholar   +1 more source

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

open access: yesFEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa   +8 more
wiley   +1 more source

Intra-Individual Variability in Vagal Control Is Associated With Response Inhibition Under Stress

open access: yesFrontiers in Human Neuroscience, 2018
Dynamic intra-individual variability (IIV) in cardiac vagal control across multiple situations is believed to contribute to adaptive cognition under stress; however, a dearth of research has empirically tested this notion. To this end, we examined 25 U.S.
Derek P. Spangler   +4 more
doaj   +1 more source

Proactively Adjusting Stopping: Response Inhibition is Faster when Stopping Occurs Frequently

open access: yesJournal of Cognition, 2023
People are able to stop actions before they are executed, and proactively slow down the speed of going in line with their expectations of needing to stop. Such slowing generally increases the probability that stopping will be successful.
Roos A. Doekemeijer   +3 more
doaj   +1 more source

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