Results 71 to 80 of about 2,704,258 (334)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Myopic decisions under negative emotions correlate with altered time perception

Frontiers in Psychology, 2015
Previous studies have obtained inconsistent findings about emotional influence on inter-temporal choice. In the present study, we first examined the effect of temporary emotional priming induced by affective pictures in a trial-to-trial paradigm on inter-
Shuchen eGuan, Lu eCheng, Ying eFan, Xianchun eLi   +3 more
doaj   +1 more source

Immune Checkpoint Inhibition in Advanced Bladder and Kidney Cancer: Responses and Further Management [PDF]

, 2021
Mamta Parikh, Thomas Powles
openalex   +1 more source

Effect of the glucocorticoid receptor antagonist Org 34850 on fast and delayed feedback of corticosterone release [PDF]

, 2007
We investigated the effect of the glucocorticoid receptor (GR) antagonist Org 34850 on fast and delayed inhibition of corticosterone secretion in response to the synthetic glucocorticoid methylprednisolone (MPL).
Craighead, Mark, Grassie, Morag, Harrison, Louse R., Lightman, Stafford L., MacSweeney, Cliona P., Spiga, Francesca, Thomson, Fiona .J., Wood, Susan A.   +7 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Alcohol affects neuronal substrates of response inhibition but not of perceptual processing of stimuli signalling a stop response [PDF]

, 2013
Alcohol impairs inhibitory control, including the ability to terminate an initiated action. While there is increasing knowledge about neural mechanisms involved in response inhibition, the level at which alcohol impairs such mechanisms remains poorly ...
A Green, A Hampshire, A Mehrabian, A Nambu, A Rey, AD Chevrier, AJ Caswell, AL Norman, AR Aron, AR Aron, AR Aron, AR Aron, AR Aron, BM Anderson, C Easdon, CA Marczinski, CA Marczinski, CA Marczinski, CD Chambers, CM Dodds, CM Steele, CN Boehler, CN Boehler, CN White, CR Guillot, CS Li, DJ Sharp, DM Dougherty, DM McCarthy, DM Torta, F Esposito, F Verbruggen, F Verbruggen, GD Logan, GE Alexander, GE Alexander, H de Wit, HM Duvernoy, Hugo Critchley, J Ashburner, J Chikazoe, J Weafer, JH Patton, JL Kenemans, JM Townshend, K Fromme, K Katanoda, K Marinkovic, K Nikolaou, K Rubia, KJ Friston, Kyriaki Nikolaou, L Boucher, LE Mulvihill, M Field, M Sano, MA Schuckit, Marcus Gray, MC Stevens, MT Fillmore, MT Fillmore, N Weiskopf, ND Volkow, NH Naqvi, R Deichmann, R Weissenborn, RB Buxton, RN Henson, RS Ross, RZ Goldstein, S Loeber, S Loeber, S Loeber, SC Matthews, SD Slotnick, T Duka, T Nichols, T Singer, Theodora Duka   +78 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Right Fronto-Subcortical White Matter Microstructure Predicts Cognitive Control Ability on the Go/No-go Task in a Community Sample

Frontiers in Human Neuroscience, 2018
Go/no-go tasks are widely used to index cognitive control. This construct has been linked to white matter microstructure in a circuit connecting the right inferior frontal gyrus (IFG), subthalamic nucleus (STN), and pre-supplementary motor area. However,
Kendra E. Hinton, Benjamin B. Lahey, Victoria Villalta-Gil, Brian D. Boyd, Benjamin C. Yvernault, Katherine B. Werts, Andrew J. Plassard, Brooks Applegate, Neil D. Woodward, Bennett A. Landman, David H. Zald   +10 more
doaj   +1 more source

Primary cilia elongation in response to interleukin-1 mediates the inflammatory response [PDF]

, 2012
Primary cilia are singular, cytoskeletal organelles present in the majority of mammalian cell types where they function as coordinating centres for mechanotransduction, Wnt and hedgehog signalling. The length of the primary cilium is proposed to modulate
A. K. T. Wann, AC Lin, AJ Espanol, AM Malone, BD Engel, BK Yoder, CA Dinarello, CG Jensen, CM Asleson, D Qian, DA Lee, E Verghese, E Verghese, EJ Michaud, EM Mokrzan, GJ Pazour, H Tukachinsky, I Memon, J Kim, JA Deane, JL Rosenbaum, JM Neugebauer, K Gardner, KJ Palmer, L Schneider, M Barzi, M Cao, M. M. Knight, MA Lancaster, MB Hovater, N Sharma, P Tummala, PA Lefebvre, PV Tran, RY Kwon, S Abdul-Majeed, S Agarwal, S Kim, S Massinen, S Mukhopadhyay, S Pritchard, S Toffoli, SC Goetz, SM Nauli, SR McGlashan, SR McGlashan, SR McGlashan, TT Chowdhury, TY Besschetnova, Y Chen, Y Ou, YH Choi   +51 more
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source