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The response regulator OmpR contributes to the pathogenicity of avian pathogenic Escherichia coli
Poultry Science, 2022 : Avian colibacillosis is a serious systemic infectious disease in poultry and caused by avian pathogenic Escherichia coli (APEC). Previous studies have shown that 2-component systems (TCSs) are involved in the pathogenicity of APEC.
Dandan Fu +8 more
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Insights into the Functions of a Prophage Recombination Directionality Factor
Viruses, 2012 Recombination directionality factors (RDFs), or excisionases, are essential players of prophage excisive recombination. Despite the essentially catalytic role of the integrase in both integrative and excisive recombination, RDFs are required to direct ...
Mireille Ansaldi +3 more
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Microorganisms, 2021 The chemotactic response regulator CheY, when phosphorylated by the phosphoryl group from phosphorylated CheA, can bind to the motor switch complex to control the flagellar motor rotation.
Dawei Gao +6 more
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Frontiers in Microbiology, 2016 The plant pathogen Agrobacterium tumefaciens carries a virulence gene system that is required for the initiation of crown gall tumors on susceptible plants. Expression of the vir genes is activated by the VirA/VirG two component regulatory system.
Arlene A. Wise, Andrew N Binns
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mSphere, 2016 For successful infection to occur, a pathogen must be able to evade or tolerate the host’s defense systems. This requires the pathogen to first recognize the host environment and then signal this response to elicit a complex adaptive program in order to ...
Kylie J. Boyce +2 more
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The LytS-type histidine kinase BtsS is a 7-transmembrane receptor that binds pyruvate
mBio, 2023 LytS/LytTR-type histidine kinase/response regulator systems regulate crucial host-specific mechanisms during infection of human or plant hosts. Escherichia coli has two of them, and the histidine kinase BtsS is a high-affinity sensor for extracellular ...
Jin Qiu +4 more
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Visualizing the Pre-Active Conformation of Response Regulator PhoBNF20D in Its apo State
Chinese Journal of Magnetic Resonance, 2019 PhoB is a response regulator of the PhoR/PhoB two-component system (TCS) in Escherichia Coli, which is involved in environmental phosphate regulation. PhoB activation is known to be mediated by Mg2+ coordination and phosphorylation of the conserved D53 ...
KOU Xin-hui +5 more
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Postępy Mikrobiologii, 2020 Two-component signal transduction systems composed of histidine sensor kinase and response regulator are involved in adaptive response of pathogenic bacteria to environmental signals by regulating gene expression involved in many physiological processes,
Raczkowska Adrianna +3 more
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Negative regulation of Th17 responses [PDF]
Seminars in Immunology, 2007 The discovery of the Th17 lineage of T helper cells and the realization that this subset was implicated in the pathogenesis of a variety of inflammatory conditions has lead to an intense effort devoted to identifying the cytokines and transcription factors that promote their development.
J S, Stumhofer, J, Silver, C A, Hunter
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Neddylation Regulation of Immune Responses
Research, 2023 Neddylation plays a vital role in post-translational modification, intricately shaping the regulation of diverse biological processes, including those related to cellular immune responses. In fact, neddylation exerts control over both innate and adaptive immune systems via various mechanisms.
Hongmei Mao, Xin Lin, Yi Sun
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