Results 81 to 90 of about 761,074 (261)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Microbial sensor variation across biogeochemical conditions in the terrestrial deep subsurface
mSystemsMicrobes can be found in abundance many kilometers underground. While microbial metabolic capabilities have been examined across different geochemical settings, it remains unclear how changes in subsurface niches affect microbial needs to sense and ...
Annelise L. Goldman +7 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Hormonal Regulation of Immune Responses
Annals of Medicine, 1994 Females have stronger immune responses than males. Female predominance in autoimmune diseases in both experimental animals and in man is also established. Sex hormones and some other steroid hormones have been shown to exert immunoregulatory effects in both in vivo and in vitro situations.
openaire +2 more sources
Two-Component Systems in Francisella Species
Frontiers in Cellular and Infection Microbiology, 2019 Bacteria alter gene expression in response to changes in their environment through various mechanisms that include signal transduction systems.
Monique L. van Hoek +5 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Translation regulation in response to stress
The FEBS JournalCell stresses occur in a wide variety of settings: in disease, during industrial processes, and as part of normal day‐to‐day rhythms. Adaptation to these stresses requires cells to alter their proteome. Cells modify the proteins they synthesize to aid proteome adaptation.
Thomas D. Williams, Adrien Rousseau
openaire +3 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Cytokinins, A classical multifaceted hormone in plant system [PDF]
Journal of Stress Physiology & Biochemistry, 2011 Today, owing to the versatile functionality and physiological importance of the phytohormone cytokinin (Ck) is a major focus of attention in contemporary wide areas of plant science.
Mohd Mazid +2 more
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