Results 61 to 70 of about 4,958,218 (328)

A Process Planning Method and Data Format for Achieving Tolerances in Stereolithography [PDF]

open access: yes, 1998
When building parts in a stereolithography apparatus (SLA), the user is faced with many decis!ons regarding the setting of process variables. To 'achieve a set of tolera~ces as closely as pOSSIble, relationships between part geometry, tolerances, and ...
Lynn, Charity M.   +2 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Combination Mechanism of Soil Dissolved Organic Matter and Cu2+ in Vegetable Fields, Forests and Dry Farmland in Lujiang County

open access: yesAgriculture
Dissolved organic matter (DOM) serves as a critical link in the migration and transformation of heavy metals at the soil–solid interface, influencing the migration behaviour and transformation processes of Cu2+ in soil.
Youru Yao   +8 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Anisotropic optical response of the diamond (111)-2x1 surface

open access: yes, 1995
The optical properties of the 2$\times$1 reconstruction of the diamond (111) surface are investigated. The electronic structure and optical properties of the surface are studied using a microscopic tight-binding approach.
A. I. Shkrebtii   +54 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Hillside urban expansion exacerbates nature and semi-nature habitat landscape fragmentation in China

open access: yesInternational Journal of Digital Earth
Hillside urban expansion (HUE) force nature and semi-nature habitats (referred as nature habitats) to migrate to higher slope areas, potentially resulting in modifications to the landscapes of these habitats, and affect biodiversity and human well-being.
Zhijian Chang   +5 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Reservoir impoundment alters surrounding plant physiological activities revealed by stable isotopes in tree rings

open access: yesEcological Indicators
Reservoir impoundment influences the growth of surrounding plants by altering the microclimate. However, the physiological mechanism of responses remains unclear.
Lian Sun   +10 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

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