Results 81 to 90 of about 3,378,607 (346)

Optimization of bioactive compound extraction from tobacco stem (Nicotiana tabacum L.) [PDF]

BIO Web of Conferences
Tobacco stem represents an underutilized agricultural by-product rich in bioactive secondary metabolites such as phenolics, flavonoids, alkaloids, terpenoids, and saponins.
Budiati Titik, Adila Putri, Djamila Siti, Atmajaya Aditya Wahyu Winadi, Bahri Syaiful   +4 more
doaj   +1 more source

Optimization design of spring hammer calibration device based on response surface method [PDF]

, 2023
Jianzhuo Gao, Xin Luo, Ningxi Wang, Long Chen   +3 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Optimization of Reaction Conditions in the Production of Gadolinium Diethylenetriamine Pentaacetate-Folate [PDF]

, 2015
A previous study has performed the laboratory-scale synthesis and characterization of Gadolinium Diethylenetriaminepentaacetate-Folate. Some parameters associated with the synthesis have been defined.
Anggraeni, A., Fauzia, R. P., Gunawan, A. H., Mutalib, A.   +3 more
core  

Thermal structure of a gas-permeable lava dome and timescale separation in its response to perturbation [PDF]

, 2009
The thermal boundary layer at the surface of a volcanic lava dome is investigated through a continuum model of the thermodynamic advection diffusion processes resulting from magmatic gas flow through the dome matrix.
Adrian J. Matthews, Balmforth, Balmforth, Barclay, Barclay, Bourgouin, Calder, Carn, Costa, Couch, Dragoni, Dzurisin, Edmonds, Edmonds, Edmonds, Elsworth, Fink, Francis, Hale, Hale, Hammouya, Herd, Hicks, Hinch, Iverson, Mark J. Cooker, Mastin, Matthews, Matthews, McNutt, McNutt, Melnik, Melnik, Nakada, Neri, Neuberg, Oppenheimer, Peter D. Hicks, Sato, Sigurdsson, Simmons, Sparks, Sparks, Spera, Taron, Urai, Vaughan, Watts, Woods, Yamasato   +49 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Tuning a fuzzy controller using quadratic response surfaces [PDF]

Response surface methodology, an alternative method to traditional tuning of a fuzzy controller, is described. An example based on a simulated inverted pendulum 'plant' shows that with (only) 15 trial runs, the controller can be calibrated using a ...
Schott, Brian, Whalen, Thomas
core   +1 more source

Dopant Spatial Distributions: Sample Independent Response Function And Maximum Entropy Reconstruction

, 1997
We demonstrate the use of maximum entropy based deconvolution to reconstruct boron spatial distribution from the secondary ion mass spectrometry (SIMS) depth profiles on a system of variously spaced boron $\delta$-layers grown in silicon.
A. Benninghoven, C. E. Shannon, D. P. Chu, D. P. Chu, E. T. Jaynes, F. N. Schwettman, G. L. Vick, H. H. Andersen, J. B. Clegg, J. Myrheim, K. Wittmaack, K. Wittmaack, K. Wittmaack, M. G. Dowsett, M. G. Dowsett, M. G. Dowsett, P. N. Allen, P. Sigmund, R. Badheka, S. F. Gull, U. Littmark   +20 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source