Results 81 to 90 of about 5,192,011 (281)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Power as an ethical concern in the Global South’s digital transformation
TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2019 The digitalization of the Global South, particularly with respect to African countries, is moving at a fast pace. This can be seen in the use of information and communications technology (ICT) in different domains such as healthcare, education, industry,
Kutoma Wakunuma
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Assessing self-responsibility in employability competencies development among Australian engineering students: introductory report [PDF]
, 2016 Self-responsibility study initially outlined the importance of ‘self-directed Adult learning’ either as the method or the outcome of education.
Ferris, T. L. J., Lazarus, D.
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
, 2008 How can companies avoid corporate responsibility falling into a management black-hole? What can managers do to take corporate responsibility forward in their organisation, even if the company overall is indifferent or at an early stage of development in ...
Grayson, David
core
Responsibility Without Wrongdoing or Blame [PDF]
, 2018 In most discussions of moral responsibility, an agent’s moral responsibility for harming or failing to aid is equated with the agent’s being blameworthy for having done wrong.
Tannenbaum, Julie
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Navigating toward acceptance of death: Home-dwelling patients in the palliative phase
BMC Palliative CareBackground As global life expectancy increases, the need for palliative care grows. Recognizing the deeply personal and diverse nature of individuals’ end-of-life experiences, palliative care for home-dwelling patients requires a flexible and person ...
Katrine Staats +2 more
doaj +1 more source
Gauging the impact of community university engagement initiatives in India
ASEAN Journal of Community Engagement, 2017 Today, the world we live inis challenged with the co-existence of ‘prosperity and poverty’. In India, inparticular, although we are witnessing staggering increase in various economicindicators, our Human Development Indicators (HDIs) remain unenviable ...
Wafa Singh
doaj +1 more source