Results 81 to 90 of about 3,686,228 (287)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Are you ready to eat less meat? Consumer segmentation based on the transtheoretical model of behaviour change

Cleaner and Responsible Consumption
Excess meat production and overconsumption have raised concerns worldwide about meat's potential negative environmental and climate impacts. Reducing these impacts requires behavioural changes among meat consumers as well as an understanding of consumers'
Bárbara Franco Lucas, Thanh Mai Ha, Franziska Götze, Minh Hai Ngo, Evelyn Markoni, Thi Lam Bui, Anh Duc Nguyen, Nhu Thinh Le, Mathilde Delley, Bao Duong Pham, Thomas A. Brunner   +10 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Enhancing sustainable innovation through workplace well-being and digital capability: A systematic literature review toward responsible and cleaner consumption

Cleaner and Responsible Consumption
This systematic literature review explores the junction of workplace well-being, digital capacity, and innovation performance in reaction to increasing calls for ethical innovation and sustainable business practices. With specific focus on Asia and China,
Qijun Li, Ilhaamie binti Abdul Ghani Azmi, Azah Anir binti Norman   +2 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Choosing clean: Do Indian consumers intend to purchase microplastic-free personal care products

Cleaner and Responsible Consumption
Plastic microbeads in personal care products have raised significant environmental concerns, prompting regulatory interventions worldwide. However, consumer intentions play a crucial role in ensuring the success of such initiatives, particularly in ...
Riya Kumbukattu Alex, Nimitha Aboobaker, Suja Purushothaman Devipriya   +2 more
doaj   +1 more source

The Consumption Response to Protectionism

SSRN Electronic Journal
Despite policy aims to support income and employment, we show that U.S. households in counties more exposed to protective tariffs spend less over time. Spending declines coincide with falling wages and persist after accounting for exposure to pass-through and retaliatory tariffs.
Lin, Chen, Shan, Hongyu, Tian, Da
openaire   +1 more source

"RG Check" responsible gambling accreditation scores for land-based gambling venues

, 2019
RG Check is a responsible gambling accreditation program developed by the Responsible Gambling Council, Ontario, Canada. It assesses individual gambling venues on hundreds of criteria based on existing responsible gambling standards and codes of practice.
Responsible Gambling Council
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

The impact of voluntary sustainability adjustments on greenhouse gas emissions from food consumption – The case of Denmark [Elektronisk resurs]

In this study we ask how a range of environmental sustainability adjustments that consumers find it easy to adopt affect the carbon footprint of their food consumption. The study is based on information about real purchases of food products and responses
Denver, Sigrid,, Nordström, Jonas,, Lund University.   +2 more
core   +2 more sources