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Structural and Functional Characterization of Reston Ebola Virus VP35 Interferon Inhibitory Domain [PDF]
Journal of Molecular Biology, 2010 Ebolaviruses are causative agents of lethal hemorrhagic fever in humans and nonhuman primates. Among the filoviruses characterized thus far, Reston Ebola virus (REBOV) is the only Ebola virus that is nonpathogenic to humans despite the fact that REBOV can cause lethal disease in nonhuman primates.
Gaya K. Amarasinghe +2 more
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Reston virus in domestic pigs in China
Archives of Virology, 2012Historically, Reston virus (RESTV) has been found to be associated with outbreaks of disease only in nonhuman primates. Its spread to domestic pigs was reported for the first time in 2008. In this study, we report the discovery, molecular detection, and phylogenetic analysis of Reston virus (RESTV) in domestic pigs in China.
Yangyang, Pan +5 more
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Structures of Ebola and Reston Virus VP35 Oligomerization Domains and Comparative Biophysical Characterization in All Ebolavirus Species [PDF]
Structure, 2019 The multifunctional virion protein 35 (VP35) of ebolaviruses is a critical determinant of virulence and pathogenesis indispensable for viral replication and host innate immune evasion. Essential for VP35 function is homo-oligomerization via a coiled-coil motif.
Luca Zinzula +2 more
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Experimental Animals, 2002 To describe the transmission pattern of natural infection with Ebola Reston (EBO-R) virus in a breeding colony, the chronological and spatial analysis of mortality during the 1996 EBO-R virus outbreak was done in this study. The EBO-R virus infection among monkeys in the facility was widespread.
Tetsuro Ikegami +2 more
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First Pig-to-Human Transmission of Ebola-Reston Virus
Lancet Infectious Diseases, The, 2009Kelly Morris
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Experimental Animals, 2002 We investigated the livers, spleens, kidneys and lungs collected from 24 cynomolgus macaques (Macaca fascicularis) naturally infected with Ebola virus subtype Reston (EBO-R) during the Philippine outbreak in 1996, in order to reveal the histopathologic findings.
Masayuki Saijo +2 more
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Development of an Immunofluorescence Method for the Detection of Antibodies to Ebola Virus Subtype Reston by the Use of Recombinant Nucleoprotein-Expressing HeLa Cells [PDF]
Microbiology and Immunology, 2002 AbstractAn indirect immunofluorescent assay (IFA) to detect Ebola virus subtype Reston (EBO‐R) antibodies was developed by the use of a HeLa cell line stably expressing EBO‐R nucleoprotein (NP). This IFA has a high specificity for the detection of EBO‐R IgG antibodies in both hyperimmune rabbit sera and monkey sera collected during an EBO‐R outbreak in
Masayuki Saijo +2 more
exaly +3 more sources
The American Journal of Tropical Medicine and Hygiene, 1996
To evaluate the potential for arthropods to serve as reservoir hosts of Ebola virus, three mosquito species, Aedes albopictus, Aedes taeniorhynchus, and Culex pipiens, and a soft tick, Ornithodoros sonrai, were inoculated with 1O2.5 plaque-forming units of Ebola Reston virus.
M J, Turell, D S, Bressler, C A, Rossi
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To evaluate the potential for arthropods to serve as reservoir hosts of Ebola virus, three mosquito species, Aedes albopictus, Aedes taeniorhynchus, and Culex pipiens, and a soft tick, Ornithodoros sonrai, were inoculated with 1O2.5 plaque-forming units of Ebola Reston virus.
M J, Turell, D S, Bressler, C A, Rossi
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Electron and immunoelectron microscopy of experimental Reston virus infection in monkeys
Proceedings, annual meeting, Electron Microscopy Society of America, 1992The tissues and fluids of five cynomolgus macaques (Macaca fasicularis) experimentally inoculated with Ebola-related Reston virus were examined by transmission electron microscopy (TEM) at various stages of disease to provide insight into the pathogenesis of this newly discovered; potential human pathogen.
Thomas W. Geisbert +2 more
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