Lactococcal mobile genetic elements harbour a diverse phage defensome rich in restriction-modification systems. [PDF]
McDonnell B +15 more
europepmc +1 more source
Uncovering the link between the SpnIII restriction modification system and LuxS in Streptococcus pneumoniae meningitis isolates. [PDF]
Agnew HN +9 more
europepmc +1 more source
Discovery of a pentose as a cytosine nucleobase modification in Shewanella phage Thanatos-1 genomic DNA mediating enhanced resistance towards host restriction systems [PDF]
David Brandt +9 more
openalex +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The early injected genomic region determines sensitivity to Type I restriction-modification defence against Autographiviridae phages. [PDF]
Martinez-Cazorla A +5 more
europepmc +1 more source
EcoR124I: from Plasmid-Encoded Restriction-Modification System to Nanodevice
James Youell, Keith Firman
openalex +2 more sources
Characterization of a CACAG pentanucleotide repeat in Pasteurella haemolytica and its possible role in modulation of a novel type III restriction-modification system [PDF]
Kate Ryan
openalex +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Regulation of a phage defence island by RptR, a novel repressor that controls restriction-modification systems in diverse bacteria. [PDF]
Zhang Y +5 more
europepmc +1 more source

