Results 171 to 180 of about 228,478 (241)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Improved genetic transformation by disarmament of type II Restriction-Modification system in Streptococcus zooepidemicus. [PDF]

3 Biotech, 2022
Gao W, Xie Y, Zuo M, Zhang G, Liu H.
europepmc   +1 more source

Cloning and expression of the Pst I restriction-modification system in Escherichia coli.

, 1981
Roxanne Y. Walder, James L. Hartley, J E Donelson, Joseph A. Walder   +3 more
openalex   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

BlihIA-A Novel Type I Restriction-Modification System from <i>Bacillus licheniformis</i> Is Sensitive to In Vitro Inhibition by ArdB Antirestriction Protein. [PDF]

Int J Mol Sci
Kudryavtseva A, Berezov R, Utkina A, Kotovskaya O, Skutel M, Trofimova A, Isaev A, Manukhov I.   +7 more
europepmc   +1 more source

Enhanced Fusobacterium nucleatum Genetics Using Host DNA Methyltransferases To Bypass Restriction-Modification Systems. [PDF]

J Bacteriol, 2022
Umaña A, Nguyen TTD, Sanders BE, Williams KJ, Wozniak B, Slade DJ.   +5 more
europepmc   +1 more source

Cloning and sequence analysis of the Stsl restriction-modification gene: presence of homology to Fokl restriction-modification enzymes

, 1992
Keiko Kita, Masaaki Suisha, Hirokazu Kotani, Hideshi Yanase, Nobuo Kato   +4 more
openalex   +2 more sources

Organization of the BcgI restriction-modification protein for the cleavage of eight phosphodiester bonds in DNA [PDF]

, 2012
Rachel M. Smith, J. Marshall, Alistair J. Jacklin, Susan E. Retter, Stephen E. Halford, Frank Sobott   +5 more
openalex   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

The restriction impacts of the Type III restriction-modification system on the transmission dynamics of antimicrobial resistance genes in <i>Campylobacter jejuni</i>. [PDF]

Front Microbiol
Qiu Y, Guo P, Tian H, Zhou Y, Wen H, Liang H.   +5 more
europepmc   +1 more source