Results 151 to 160 of about 18,327,370 (242)

KpnBI is the prototype of a new family (IE) of bacterial type I restriction-modification system

, 2004
restriction-modification ...
S. Magaki, V. Chin, J. Ryu, V. Valinluck
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Further delineation of Borrelia burgdorferi Restriction-Modification system and understanding antibiotic resistance in Borrelia afzelii

, 2015
The aim of this thesis was to further the understanding of restriction-modification and the homology within the restriction-modification genes in various Borrelia species including Borrelia afzelii as well as to investigate spontaneous antibiotic ...
DEMCHYSHYN, Stepan Stepanovych
core  

Acquisition of a novel restriction modification system regulates genetic flux and gene expression in the hypervirulent and globally disseminated CC17 lineage of group B Streptococcus. [PDF]

Nucleic Acids Res
Alves J, Crestani C, Marroquin SM, Johnston ABE, Ring N, Bowen C, Reglinski M, Doran KS, Zadoks RN, Lynskey NN.   +9 more
europepmc   +1 more source

Analysis of a phase-variable restriction modification system of the human gut symbiont Bacteroides fragilis. [PDF]

Nucleic Acids Res, 2020
Ben-Assa N, Coyne MJ, Fomenkov A, Livny J, Robins WP, Muniesa M, Carey V, Carasso S, Carasso S, Gefen T, Jofre J, Roberts RJ, Comstock LE, Geva-Zatorsky N.   +13 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

How to Unmask an Unknown: The Restriction-Modification System <i>Mho</i>VII of <i>Mycoplasma hominis</i> Expresses Two Complementary Methylation Activities in One Enzyme. [PDF]

Int J Mol Sci
Vogelgsang L, Bäcker D, Scharf SA, Nisar A, Dilthey AT, Henrich B.   +5 more
europepmc   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

BlihIA-A Novel Type I Restriction-Modification System from <i>Bacillus licheniformis</i> Is Sensitive to In Vitro Inhibition by ArdB Antirestriction Protein. [PDF]

Int J Mol Sci
Kudryavtseva A, Berezov R, Utkina A, Kotovskaya O, Skutel M, Trofimova A, Isaev A, Manukhov I.   +7 more
europepmc   +1 more source