Results 31 to 40 of about 1,391,910 (241)

Restriction-modification systems of M. gallisepticum S6.

open access: yes, 2022
Arrows represent the ORFs; grey, blue, green, and orange colors indicate genes hsdC (controller protein), hsdM (methyltransferase), hsdS (specificity subunit), and hsdR (restriction subunit), respectively. Ori–origin of replication.
Vadim M. Govorun (213423)   +8 more
core   +1 more source

Domain movement within a gene: a novel evolutionary mechanism for protein diversification. [PDF]

open access: yesPLoS ONE, 2011
A protein function is carried out by a specific domain localized at a specific position. In the present study, we report that, within a gene, a specific amino acid sequence can move between a certain position and another position.
Yoshikazu Furuta   +3 more
doaj   +1 more source

DNA methylation assessed by SMRT sequencing is linked to mutations in Neisseria meningitidis isolates [PDF]

open access: yes, 2015
The Gram-negative bacterium Neisseria meningitidis features extensive genetic variability. To present, proposed virulence genotypes are also detected in isolates from asymptomatic carriers, indicating more complex mechanisms underlying variable ...
Gerd Pluschke   +26 more
core   +1 more source

Functional comparison of anti-restriction and anti-methylation activities of ArdA, KlcA, and KlcAHS from Klebsiella pneumoniae

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Anti-restriction proteins are typically encoded by plasmids, conjugative transposons, or phages to improve their chances of entering a new bacterial host with a type I DNA restriction and modification (RM) system.
Huimin Chen   +6 more
doaj   +1 more source

Effect of a standardised dietary restriction protocol on multiple laboratory strains of Drosophila melanogaster [PDF]

open access: yes, 2009
Background: Outcomes of lifespan studies in model organisms are particularly susceptible to variations in technical procedures. This is especially true of dietary restriction, which is implemented in many different ways among laboratories.
Linda Partridge   +25 more
core   +2 more sources

Avoidance of recognition sites of restriction-modification systems is a widespread but not universal anti-restriction strategy of prokaryotic viruses

open access: yesBMC Genomics, 2018
Background Restriction-modification (R-M) systems protect bacteria and archaea from attacks by bacteriophages and archaeal viruses. An R-M system specifically recognizes short sites in foreign DNA and cleaves it, while such sites in the host DNA are ...
I. S. Rusinov   +4 more
doaj   +1 more source

Restriction and decay for flat hypersurfaces [PDF]

open access: yes, 2002
In the first part we consider restriction theorems for hypersurfaces [Gamma] in Rn, with the affine curvature [fòrmula] introduced as a mitigating factor. Sjolin, [19], showed that there is a universal restriction theorem for all convex curves in R2.
Carbery, Anthony   +3 more
core   +1 more source

REMP software to introduce a screening REstriction site in site-directed Mutagenesis Primer

open access: yesSoftwareX, 2021
Insertion of silent mutations allowing for restriction site modification aids in the screening of successful mutants during site directed mutagenesis. Introducing a new restriction site requires the analysis of degenerate sequences within mutant primer ...
Madhavi Latha Yadav Bangaru, PhD   +3 more
doaj   +1 more source

Historical Aspects of Restriction Endonucleases as Intelligent Scissors for Genetic Engineering

open access: yesFermentation, 2023
Restriction endonucleases are a component of restriction–modification systems, where the main biological function is to protect bacterial cells from incoming foreign DNA molecules.
Irina V. Alekseeva, Nikita A. Kuznetsov
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

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