Results 41 to 50 of about 728,418 (291)

Restriction Endonucleases and Modification Methylases

Current Opinion in Structural Biology, 1993
Restriction endonucleases and modification methylases offer excellent systems for studying protein-DNA interactions. The past year has seen the experimental verification of some aspects of the catalytic mechanisms of both types of enzyme.
Anderson, J. E.
core   +2 more sources

To be or not to be: regulation of restriction–modification systems and other toxin–antitoxin systems [PDF]

Nucleic Acids Research, 2013
One of the simplest classes of genes involved in programmed death is that containing the toxin–antitoxin (TA) systems of prokaryotes. These systems are composed of an intracellular toxin and an antitoxin that neutralizes its effect.
Iwona Mruk, I. Kobayashi
semanticscholar   +3 more sources

Bacterial autoimmunity due to a restriction-modification system [PDF]

Current Biology, 2016
Restriction-modification (RM) systems represent a minimal and ubiquitous biological system of self/non-self discrimination in prokaryotes [1], which protects hosts from exogenous DNA [2]. The mechanism is based on the balance between methyltransferase (M)
Bergmiller, Tobias ; https://orcid.org/, Wakamoto, Yuichi, Guet, Calin C ; https://orcid.org/, Kussell, Edo, Okura, Reiko, Pleska, Maros ; https://orcid.org/, Qian, Long   +6 more
core   +3 more sources

Complete genome assembly and methylome dissection of Methanococcus aeolicus PL15/Hp

Frontiers in Microbiology, 2023
Although restriction-modification systems are found in both Eubacterial and Archaeal kingdoms, comparatively less is known about patterns of DNA methylation and genome defense systems in archaea.
Alexey Fomenkov, Peter Weigele, Colleen McClung, Casey Madinger, Richard J. Roberts   +4 more
doaj   +1 more source

Bacterial DNA methyltransferase: A key to the epigenetic world with lessons learned from proteobacteria

Frontiers in Microbiology, 2023
Epigenetics modulates expression levels of various important genes in both prokaryotes and eukaryotes. These epigenetic traits are heritable without any change in genetic DNA sequences. DNA methylation is a universal mechanism of epigenetic regulation in
Qun Gao, Qun Gao, Shuwei Lu, Shuwei Lu, Yuwei Wang, Longgui He, Longgui He, Mingshu Wang, Mingshu Wang, Mingshu Wang, Renyong Jia, Renyong Jia, Renyong Jia, Shun Chen, Shun Chen, Shun Chen, Dekang Zhu, Dekang Zhu, Dekang Zhu, Mafeng Liu, Mafeng Liu, Mafeng Liu, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Qiao Yang, Qiao Yang, Qiao Yang, Ying Wu, Ying Wu, Ying Wu, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Juan Huang, Juan Huang, Juan Huang, Sai Mao, Sai Mao, Sai Mao, Xumin Ou, Xumin Ou, Xumin Ou, Di Sun, Di Sun, Di Sun, Bin Tian, Bin Tian, Bin Tian, Anchun Cheng, Anchun Cheng, Anchun Cheng   +51 more
doaj   +1 more source

Transcription regulation of the EcoRV restriction-modification system [PDF]

Nucleic Acids Research, 2005
When a plasmid containing restriction-modification (R-M) genes enters a naïve host, unmodified host DNA can be destroyed by restriction endonuclease. Therefore, expression of R-M genes must be regulated to ensure that enough methyltransferase is produced and that host DNA is methylated before the endonuclease synthesis begins.
Semenova, Ekaterina, Minakhin, Leonid, Bogdanova, Ekaterina, Nagornykh, Maxim, Vasilov, Anatoliy, Heyduk, Tomasz, Solonin, Alexander, Zakharova, Marina, Severinov, Konstantin   +8 more
openaire   +2 more sources

Restriction-modification systems and plasmids

, 2023
This folder contains supplementary data files for the paper Restriction-modification systems have shaped the evolution and distribution of plasmids across bacteria (2022) Liam P. Shaw, Eduardo P. C. Rocha, R. Craig MacLean.
Liam Shaw (5487083)
core   +1 more source

Plasmid pEC156, a Naturally Occurring Escherichia coli Genetic Element That Carries Genes of the EcoVIII Restriction-Modification System, Is Mobilizable among Enterobacteria. [PDF]

PLoS ONE, 2016
Type II restriction-modification systems are ubiquitous in prokaryotes. Some of them are present in naturally occurring plasmids, which may facilitate the spread of these systems in bacterial populations by horizontal gene transfer.
Olesia Werbowy, Tadeusz Kaczorowski
doaj   +1 more source

Impact of target site distribution for Type I restriction enzymes on the evolution of methicillin-resistant Staphylococcus aureus (MRSA) populations. [PDF]

, 2013
A limited number of Methicillin-resistant Staphylococcus aureus (MRSA) clones are responsible for MRSA infections worldwide, and those of different lineages carry unique Type I restriction-modification (RM) variants.
Dryden, David T. F., White, John H., Stephanou, AS, Cooper, Laurie P., Cooper, LP, Houston, PJ, Lindsay, JA, Chen, K, Dryden, DT, Roberts, Gareth A., Lindsay, Jodi A., Chen, Kai, Roberts, GA, White, JH, Stephanou, Augoustinos S., Houston, Patrick J.   +15 more
core   +1 more source

Cloning and Expression of the BalI Restriction-modification System [PDF]

Nucleic Acids Research, 1996
BalI, a type II restriction-modification (R-M) system from the bacterium, Brevibacterium albidum, recognizes the DNA sequence 5'-TGGCCA-3'. We cloned the genes encoding the BalI restriction endonuclease and methyltransferase and expressed them in Escherichia coli. The two genes were aligned tail-to-tail and their termination codons overlapped.
H, Ueno, I, Kato, Y, Ishino
openaire   +2 more sources