Bacterial restriction-modification systems: mechanisms of defense against phage infection. [PDF]
Biophys RepKang H, Gao A, Zhu Y.
europepmc +2 more sources
DNA methylation by three Type I restriction modification systems of Escherichia coli does not influence gene regulation of the host bacterium. [PDF]
Nucleic Acids Res, 2021 Mehershahi KS, Chen SL.
europepmc +2 more sources
DNA sequence repeats identify numerous Type I restriction-modification systems that are potential epigenetic regulators controlling phase-variable regulons; phasevarions. [PDF]
FASEB J, 2020 Over recent years several examples of randomly switching methyltransferases, associated with Type III restriction‐modification (R‐M) systems, have been described in pathogenic bacteria.
Atack JM +4 more
europepmc +2 more sources
Complete genome assembly and methylome dissection of Methanococcus aeolicus PL15/Hp
Frontiers in Microbiology, 2023 Although restriction-modification systems are found in both Eubacterial and Archaeal kingdoms, comparatively less is known about patterns of DNA methylation and genome defense systems in archaea.
Alexey Fomenkov +4 more
doaj +1 more source
Restriction-modification systems and plasmids
, 2023 This folder contains supplementary data files for the paper Restriction-modification systems have shaped the evolution and distribution of plasmids across bacteria (2022) Liam P. Shaw, Eduardo P. C. Rocha, R. Craig MacLean.
Liam Shaw (5487083)
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Enhanced transformation efficiency of recalcitrant Bacillus cereus and Bacillus weihenstephanensis isolates upon in vitro methylation of plasmid DNA [PDF]
, 2008 Digestion patterns of chromosomal DNAs of Bacillus cereus and Bacillus weihenstephanensis strains suggest that Sau3AI-type restriction modification systems are widely present among the isolates tested.
Abee, T. +5 more
core +1 more source
Plasmid pEC156, a Naturally Occurring Escherichia coli Genetic Element That Carries Genes of the EcoVIII Restriction-Modification System, Is Mobilizable among Enterobacteria. [PDF]
PLoS ONE, 2016 Type II restriction-modification systems are ubiquitous in prokaryotes. Some of them are present in naturally occurring plasmids, which may facilitate the spread of these systems in bacterial populations by horizontal gene transfer.
Olesia Werbowy, Tadeusz Kaczorowski
doaj +1 more source
Structural and mutagenic analysis of the RM controller protein C.Esp1396I [PDF]
, 2014 Bacterial restriction-modification (RM) systems are comprised of two complementary enzymatic activities that prevent the establishment of foreign DNA in a bacterial cell: DNA methylation and DNA restriction.
Martin, Richard N. A. +8 more
core +2 more sources
Impact of target site distribution for Type I restriction enzymes on the evolution of methicillin-resistant Staphylococcus aureus (MRSA) populations. [PDF]
, 2013 A limited number of Methicillin-resistant Staphylococcus aureus (MRSA) clones are responsible for MRSA infections worldwide, and those of different lineages carry unique Type I restriction-modification (RM) variants.
Dryden, David T. F. +15 more
core +1 more source
Genetic manipulation of Staphylococci – Breaking through the barrier.
Frontiers in Cellular and Infection Microbiology, 2012 Most strains of Staphylococcus aureus and Staphylococcus epidermidis possess a strong restriction barrier that hinders exchange of DNA. Recently, major advances have been made in identifying and characterizing the restriction-modification systems ...
Ian R Monk, Timothy J Foster
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