Restriction-modification systems in Mycoplasma spp [PDF]
Genetics and Molecular Biology, 2007 Restriction and Modification (R-M) systems are present in all Mycoplasma species sequenced so far. The presence of these genes poses barriers to gene transfer and could protect the cell against phage infections.
Marcelo Brocchi +2 more
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IS-linked movement of a restriction-modification system. [PDF]
PLoS ONE, 2011 Potential mobility of restriction-modification systems has been suggested by evolutionary/bioinformatic analysis of prokaryotic genomes. Here we demonstrate in vivo movement of a restriction-modification system within a genome under a laboratory ...
Noriko Takahashi +4 more
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Dependence of post-segregational killing mediated by Type II restriction–modification systems on the lifetime of restriction endonuclease effective activity [PDF]
mBioPlasmid-borne Type II restriction–modification (RM) systems mediate post-segregational killing (PSK). PSK is thought to be caused by the dilution of restriction and modification enzymes during cell division, resulting in accumulation of unmethylated DNA ...
Svetlana Kozlova +3 more
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Organization of restriction-modification systems
Nucleic Acids Research, 1991 The genes for over 100 restriction-modification systems have now been cloned, and approximately one-half have been sequenced. Despite their similar function, they are exceedingly heterogeneous.
Geoffrey G. Wilson
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Understanding key features of bacterial restriction-modification systems through quantitative modeling [PDF]
BMC Syst Biol, 2017 Restriction-modification (R-M) systems are rudimentary bacterial immune systems. The main components include restriction enzyme (R), which cuts specific unmethylated DNA sequences, and the methyltransferase (M), which protects the same DNA sequences. The
Zdobnov, Evgeny +11 more
core +3 more sources
Is the Evolution of
mSystems, 2016 Salmonella enterica subsp. enterica bacteria are highly diverse foodborne pathogens that are subdivided into more than 1,500 serovars. The diversity is believed to result from mutational evolution, as well as intra- and interspecies recombination that ...
Louise Roer +6 more
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The role of DNA restriction-modification systems in the biology of Bacillus anthracis [PDF]
Frontiers in Microbiology, 2016 Restriction-modification (R-M) systems are widespread among prokaryotes and, depending on their type, may be viewed as selfish genetic elements that persist as toxin-antitoxin modules or as cellular defense systems against phage infection.
Ramakrishnan eSitaraman
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Regulation of genetic flux between bacteria by restriction–modification systems [PDF]
Proc Natl Acad Sci U S A, 2016 International audienceRestriction–modification (R-M) systems are often regarded as bacte-ria's innate immune systems, protecting cells from infection by mobile genetic elements (MGEs). Their diversification has been recently associated with the emergence
Touchon, Marie +2 more
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Restriction-modification systems have shaped the evolution and distribution of plasmids across bacteria. [PDF]
Nucleic Acids Res, 2023 Many novel traits such as antibiotic resistance are spread by plasmids between species. Yet plasmids have different host ranges. Restriction-modification systems (R-M systems) are by far the most abundant bacterial defense system and therefore represent ...
Shaw LP, Rocha EPC, MacLean RC.
europepmc +2 more sources
The Restriction–Modification Systems of Clostridium carboxidivorans P7 [PDF]
Microorganisms, 2023 Clostridium carboxidivorans P7 (DSM 15243) is a bacterium that converts syngas (a mixture of CO, H2, and CO2) into hexanol. An optimized and scaled-up industrial process could therefore provide a renewable source of fuels and chemicals while consuming ...
Patrick Kottenhahn +4 more
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