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REBASE--restriction enzymes and methylases [PDF]
Nucleic Acids Research, 1993 REBASE is a comprehensive database of information about restriction enzymes and related proteins. It contains published and unpublished references, recognition and cleavage sites, isoschizomers, commercial availability, methylation sensitivity, crystal and sequence data.
Richard J. Roberts, Dana Macelis
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Cold Spring Harbor Protocols, 2021 Restriction enzymes provided the foundation on which molecular cloning was built, and they remain as essential tools in current recombinant DNA technology. The three classes of restriction enzymes and their features are introduced here.
Michael R, Green, Joseph, Sambrook
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Restriction enzymes and their isoschizomers [PDF]
Nucleic Acids Research, 1987 Since the last compilation of restriction enzymes (1), 300 new entries have been added including 12 new specificities. With the growing size of this database and the recognition that the most widespread use of the information is as a database for computer programs predicting restriction enzyme cleavage patterns, the new format has been continued ...
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REBASE: restriction enzymes and methyltransferases [PDF]
Nucleic Acids Research, 2003 REBASE contains comprehensive information about restriction enzymes, DNA methyltransferases and related proteins such as nicking enzymes, specificity subunits and control proteins. It contains published and unpublished references, recognition and cleavage sites, isoschizomers, commercial availability, crystal and sequence data. Homing endonucleases are
Tamas Vincze +3 more
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The Architecture of Restriction Enzymes [PDF]
Structure, 2013 In this issue of Structure, Lyumkis and colleagues describe a high resolution structure of a polymerized form of the SgrAI restriction enzyme, which shows that it forms a helical assembly with four enzyme molecules per turn of the helix. The DNA is arranged on the periphery of the protein helix pointing away from the helical axis.
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A Sliding Restriction Enzyme Pauses [PDF]
Structure, 2007 In this issue of Structure, Aggarwal and colleagues (Townson et al., 2007) present the crystal structure of the restriction endonuclease BstYI in complex with a near-cognate substrate. This structure most likely reflects the conformation BstYI adopts as it scans DNA and pauses upon encountering a site similar to its recognition sequence.
Wolfgang Wende, Alfred Pingoud
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Biomolecular computers with multiple restriction enzymes [PDF]
Genetics and Molecular Biology, 2017 The development of conventional, silicon-based computers has several limitations, including some related to the Heisenberg uncertainty principle and the von Neumann "bottleneck". Biomolecular computers based on DNA and proteins are largely free of these disadvantages and, along with quantum computers, are reasonable alternatives to their conventional ...
Sakowski, Sebastian +5 more
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Restricting SBH Ambiguity via Restriction Enzymes
Discrete Applied Mathematics, 2002 AbstractSequencing by hybridization (SBH) is a proposed approach to DNA sequencing. The SBH-spectrum of the target sequence is a list of all k-mers occurring at least once in the sequence. Sequencing is successful if the SBH-spectrum is a result of only that sequence and ambiguous otherwise.
Steven Skiena, Sagi Snir
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Type I restriction enzymes and their relatives [PDF]
Nucleic Acids Research, 2013 Type I restriction enzymes (REases) are large pentameric proteins with separate restriction (R), methylation (M) and DNA sequence-recognition (S) subunits. They were the first REases to be discovered and purified, but unlike the enormously useful Type II REases, they have yet to find a place in the enzymatic toolbox of molecular biologists.
Loenen, Wil A M +3 more
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REBASE--restriction enzymes and DNA methyltransferases [PDF]
Nucleic Acids Research, 2004 REBASE is a comprehensive database of information about restriction enzymes, DNA methyltransferases and related proteins involved in restriction-modification. It contains both published and unpublished work with information about recognition and cleavage sites, isoschizomers, commercial availability, crystal and sequence data.
Roberts, Richard J. +3 more
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