Restriction enzymes - Open Access .click

Nature New Biology, 1973
Restriction endonuclease EcoRII makes about twenty double-stranded breaks per molecule of λh80 DNA. The 5′-terminal sequences are pC-C-A-G-G and pC-C-T-G-G. These are complementary and rotationally symmetrical, showing how the enzyme may produce DNA fragments with short cohesive ends.
C H, Bigger, K, Murray, N E, Murray
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Restriction enzymes in cells, not eppendorfs

Trends in Microbiology, 1994
Restriction enzymes are essential reagents to molecular biologists, but their relevance to bacterial populations is less obvious. Most bacteria encode restriction and modification systems and these are commonly considered to be a barrier to phage infection. Current evidence also supports a more general role for them in genetic recombination.
G, King, N E, Murray
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ATP-dependent restriction enzymes

2000
The phenomenon of restriction and modification (R-M) was first observed in the course of studies on bacteriophages in the early 1950s. It was only in the 1960s that work of Arber and colleagues provided a molecular explanation for the host specificity.
Rao, Desirazu N, Saha, Swati, Krishnamurthy, Vinita +2 more
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enzyme
molecular biology
chemistry

dna restriction enzymes
base sequence
substrate specificity

dna methylation
computer science
bacteria