Results 261 to 270 of about 2,915,798 (345)

Methylation and Expression Analysis of POU4F2, HOXA9, RBM46, and TSGA10 Genes in Bladder Cancer Using Methyl-Sensitive Restriction Enzyme PCR (MSRE-PCR)

Mahdipour S, Modarressi MH, Noruzinia M
openalex   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Characterization of Leishmania infantum Isolates from Wild Leporids in the Community of Madrid (Spain). [PDF]

Vet Sci
Ortega-García MV, García N, Domínguez M, Moreno I.   +3 more
europepmc   +1 more source

Restriction Enzyme Generated Next-Generation Sequencing Libraries and Genetic Risk Modifiers of BRCA1 Mutation Carriers

, 2016
Bradley M. Downs
openalex   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Amino acids metabolism: a potential target for cancer treatment. [PDF]

Mol Cancer
Ren S, Zhou X, Wang Z, Yuan K.
europepmc   +1 more source

Restriction enzymes.

Archives of pathology & laboratory medicine, 1990
openaire   +1 more source

Application of multiple enzyme restriction fragment length polymorphism analysis and microchip electrophoresis for estimation of antibiotic-tolerant bacterial group

, 2008
K. Watanabe
openalex   +2 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

A pentose, as a cytosine nucleobase modification in <i>Shewanella</i> phage Thanatos genomic DNA, mediates enhanced resistance toward host restriction systems. [PDF]

Appl Environ Microbiol
Brandt D, Dörrich AK, Persicke M, Kemmler A, Leonhard T, Haak M, Nölting S, Ruwe M, Schmid N, Thormann KM, Kalinowski J.   +10 more
europepmc   +1 more source