Results 181 to 190 of about 1,662,191 (275)

EIAV encodes an accessory protein that antagonizes the host restriction factor equine tetherin. [PDF]

Proc Natl Acad Sci U S A
Bai B, Zhang X, Zhang M, Ma W, Li J, Zhang H, Na L, Guo X, Lin Y, Wang XF, Wang X.   +10 more
europepmc   +1 more source

The HIV Restriction Factor Profile in the Brain Is Associated with the Clinical Status and Viral Quantities. [PDF]

Viruses, 2023
Mohammadzadeh N, Zhang N, Branton WG, Zghidi-Abouzid O, Cohen EA, Gelman BB, Estaquier J, Kong L, Power C.   +8 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Bacterial effector screening reveals RNF214 as a virus restriction factor in mammals. [PDF]

PLoS Pathog
Embry A, Schad DF, Rex EA, Alto NM, Gammon DB.   +4 more
europepmc   +1 more source

The SMC5/6 complex: An emerging antiviral restriction factor that can silence episomal DNA. [PDF]

PLoS Pathog, 2023
Irwan ID, Cullen BR.
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Sp140L functions as a herpesvirus restriction factor suppressing viral transcription and activating interferon-stimulated genes. [PDF]

Proc Natl Acad Sci U S A
Cable JM, Wongwiwat W, Grabowski JC, White RE, Luftig MA.   +4 more
europepmc   +1 more source

The RNA Interference Effector Protein Argonaute 2 Functions as a Restriction Factor Against SARS-CoV-2. [PDF]

J Mol Biol, 2023
Lopez-Orozco J, Fayad N, Khan JQ, Felix-Lopez A, Elaish M, Rohamare M, Sharma M, Falzarano D, Pelletier J, Wilson J, Hobman TC, Kumar A.   +11 more
europepmc   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

3A and 2B proteins of SVA play chess game with host restriction factor DDX23 by apoptotic pathway. [PDF]

J Virol
Li J, Lin H, Zhou Y, Lei Z, Wang X, Bi R, Liu X, Wang J, Zhang H, Wang X, Liu J, Bo Z, Shen H, Yan J, Tong R, Xue Y, Zhuansun M, Zhou J, Suo X, Chang X, Yin Z, Sun P, Li L.   +22 more
europepmc   +1 more source