Results 251 to 260 of about 1,662,191 (275)
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
SIAM Journal on Discrete Mathematics, 1988
Summary: A two-factor of G consists of disjoint cycles that cover V(G). The authors consider the existence problem for two-factors in which the cycles are restricted to having lengths from a prescribed (possibly infinite) set of integers. Theorems are presented which derive the existence of such restricted two-factors in G from their existence in G-u ...
Hell, Pavol +3 more
openaire +1 more source
Summary: A two-factor of G consists of disjoint cycles that cover V(G). The authors consider the existence problem for two-factors in which the cycles are restricted to having lengths from a prescribed (possibly infinite) set of integers. Theorems are presented which derive the existence of such restricted two-factors in G from their existence in G-u ...
Hell, Pavol +3 more
openaire +1 more source
Restrictive factors in strabismus
Survey of Ophthalmology, 1983Either muscle weakness (paresis) or mechanical restrictions can account for diminished ocular rotation. In practice, restrictions are more commonly seen. The forced duction test, differential intraocular pressure measurement and saccadic velocity studies can all assist in documenting the presence of restriction.
openaire +2 more sources
1992
It is known that human complement is more efficient at lysing erythrocytes of other species than at lysing homologous erythrocytes. This phenomenon has been called homologous species restriction (Hansch et al. 1981) of complement- mediated hemolysis. Human complement is restricted by at least three proteins known so far.
openaire +2 more sources
It is known that human complement is more efficient at lysing erythrocytes of other species than at lysing homologous erythrocytes. This phenomenon has been called homologous species restriction (Hansch et al. 1981) of complement- mediated hemolysis. Human complement is restricted by at least three proteins known so far.
openaire +2 more sources
Evolutionary genomics and HIV restriction factors
Current Opinion in HIV and AIDS, 2015To provide updated insights into innate antiviral immunity and highlight prototypical evolutionary features of well characterized HIV restriction factors.Recently, a new HIV restriction factor, Myxovirus resistance 2, has been discovered and the region/residue responsible for its activity identified using an evolutionary approach.
Pyndiah Nitisha +2 more
openaire +2 more sources
Adjustment factors for restricted rainfall
Australasian Journal of Water Resources, 20086-minute rainfall data were used to calculate average adjustment factors for rainfall durations 1, 2, 3, 6, 12 and 24 hours at seven locations (Adelaide, Brisbane, Darwin, Hobart, Melbourne, Perth and Sydney). When combined with results from published studies, average values of 1.14 for 24-hour annual maximum rainfalls and 1.16 for sub-daily rainfalls ...
W Boughton, D Jakob
openaire +1 more source
Restriction Factors in HIV-1 Disease Progression
Current HIV Research, 2015About 35 million people worldwide were living with HIV-1 at the end of 2013 and over 25 million have already died of AIDS. AIDS patients show high variability in the speed of disease progression in the absence of treatment. While certain immunological traits have been shown to correlate with accelerated or slowed progression in some subjects, including
Natacha, Merindol, Lionel, Berthoux
openaire +2 more sources
Restriction factors regulating human herpesvirus infections
Trends in ImmunologyHerpesviruses are DNA viruses and the cause of diseases ranging from mild skin conditions to severe brain diseases. Mammalian antiviral host defense comprises an array of mechanisms, including restriction factors (RFs), which block specific steps in viral replication cycles.
Serrero, Manutea C., Paludan, Søren R.
openaire +2 more sources