Results 81 to 90 of about 1,662,191 (275)

ASCT2 inhibits HIV-1 infectivity by promoting the incorporation of a gp160/ASCT2 complex into virions

mBio
Restriction factors are type I interferon (IFN)-inducible proteins that provide an early line of defense against HIV-1. Our current findings propose the amino acid transporter ASCT2 as a new host plasma membrane transporter that restricts the infectivity
Luciana Morellatto Ruggieri, Eri Miyagi, Sandra Kao, Hideki Saito, Aymé Drake Figueredo, Haruki Kitamura, María I. Colombo, Klaus Strebel   +7 more
doaj   +1 more source

Contribution of the Major ND10 Proteins PML, hDaxx and Sp100 to the Regulation of Human Cytomegalovirus Latency and Lytic Replication in the Monocytic Cell Line THP-1

Viruses, 2015
Promyelocytic leukemia nuclear bodies, also termed nuclear domain 10 (ND10), have emerged as nuclear protein accumulations mediating an intrinsic cellular defense against viral infections via chromatin-based mechanisms, however, their contribution to the
Nadine Wagenknecht, Nina Reuter, Myriam Scherer, Anna Reichel, Regina Müller, Thomas Stamminger   +5 more
doaj   +1 more source

The credit supply channel of monetary policy: evidence from a FAVAR model with sign restrictions [PDF]

, 2016
We test whether the credit channel of the monetary policy was present in the United States' economy from January 2001 to April 2016. To this end, we use a factor-augmented vector autoregression, and we impose sensible theoretical sign restrictions in our
Holguín, Juan S., Uribe Gil, Jorge Mario   +1 more
core   +1 more source

The Restriction Factors of Human Immunodeficiency Virus [PDF]

Journal of Biological Chemistry, 2012
Cellular proteins called "restriction factors" can serve as powerful blockades to HIV replication, but the virus possesses elaborate strategies to circumvent these barriers. First, we discuss general hallmarks of a restriction factor. Second, we review how the viral Vif protein protects the viral genome from lethal levels of cDNA deamination by ...
Reuben S, Harris, Judd F, Hultquist, David T, Evans   +2 more
openaire   +2 more sources

Criterion‐Related Validity of the Neuropsychological Quick Assessment for Screening Cognitive, Motor, and Behavioral Impairments in Patients With Pediatric Brain Tumors: An Observational Pilot Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neuropsychological complications may impair the qualitative prognosis of patients with pediatric brain tumors. However, multifaceted evaluations cannot be conducted in all patients because they are time consuming and burdensome for patients.
Ami Tabata, Keita Ueda, Tsukasa Ueno, Katsutsugu Umeda, Kentaro Ueno, Kanade Tanaka, Noyuri Nishida, Rie Yamawaki, Megumi Nukui, Yoshiki Arakawa   +9 more
wiley   +1 more source

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Bootstraping cointegration tests under structural co-breaks: a robust extended ECM test [PDF]

, 1998
The aim of the paper is the analysis of ECM bootstrap cointegration tests under structural breaks. Classical ECM tests depend on sorne nuisance parameters, which is an undesirable feature for empirical applications.
Arranz, Miguel A., Escribano, Álvaro
core   +1 more source

Factorization Systems for Restriction Categories

Theory and Applications of Categories
Latent fibrations [\textit{R. Cockett} et al., Theory Appl. Categ. 36, 423--491 (2021; Zbl 1467.18009)] are the analogue of fibrations for restriction categories [\textit{J. R. B. Cockett} and \textit{S. Lack}, Theor. Comput. Sci. 270, No. 1--2, 223--259 (2002; Zbl 0988.18003); Theor. Comput. Sci. 294, No.
Cockett, Robin, Cruttwell, G. S. H., Gallagher, Jonathan, Pronk, Dorette   +3 more
openaire   +2 more sources

HIV-1 Vif: A guardian of the virus that opens up a new era in the research field of restriction factors

Frontiers in Microbiology, 2013
The research on Vif protein had started in late 80s right after HIV-1 was cloned, and the function of Vif had been a mystery for a long time. However, the research on Vif has finally lead to the identification of APOBEC3G, which opens up the new era in ...
Akifumi eTakaori-Kondo, Keisuke eShindo
doaj   +1 more source

Husimi-Wigner representation of chaotic eigenstates

, 2007
Just as a coherent state may be considered as a quantum point, its restriction to a factor space of the full Hilbert space can be interpreted as a quantum plane.
Carvalho, Andre R. R., de Almeida, Alfredo M. Ozorio, Kenfack, Anatole, Rost, Jan M., Toscano, Fabricio   +4 more
core   +1 more source