Results 91 to 100 of about 2,795,666 (307)

The Landscape of Long Non‐Coding RNAs Provides Insights Into the Domestication and Improvement of Pear Fruit

Advanced Science, EarlyView.
This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.
Bobo Song, Peilin Han, Jiaming Li, Xiaolong Li, Xiang Zhang, Jing Fan, Dongliang Liu, Jianfa Cai, Lingchao Zhang, Jun Wu   +9 more
wiley   +1 more source

A comparison between CHROMagar, PCR-RFLP and PCR-FSP for identification of Candida species

Current Medical Mycology, 2017
Background and Purpose: The epidemiological alteration in the distribution of Candida species, as well as the significantly increasing trend of either intrinsic or acquired resistance of some of these fungi highlights the need for a reliable method for ...
Zahra Jafari, Marjan Motamedi, Nilufar Jalalizand, Gholam Reza Shokoohi, Arezu Charsizadeh, Hossein Mirhendi   +5 more
doaj  

Molecular techniques for the study and diagnosis of parasite infection

Journal of Venomous Animals and Toxins including Tropical Diseases, 2011
In parasitology, routine laboratory diagnosis involves conventional methods, such as optical microscopy, used for the morphological identification of parasites. Currently, molecular biology techniques are increasingly used to diagnose parasite structures
RG Tavares, R Staggemeier, ALP Borges, MT Rodrigues, LA Castelan, J Vasconcelos, ME Anschau, SM Spalding   +7 more
doaj   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

Possibilities of using nested PCR-RFLP for taxonomic identification of L3 larvae of the family Trichostrongylidae, Leiper, 1912

Российский паразитологический журнал
The purpose of the research is to apply molecular genetic research methods to identify the taxonomic affiliation of gastrointestinal parasitic sheep nematodes of the family Trichostrongylidae using nested PCR followed by the restriction fragment length ...
I. A. Pimenov, I. M. Odoevskaya, A. M. Plieva, A. I. Varlamova   +3 more
doaj   +1 more source

Análisis de polimorfismos en los genes tripanotión reductasa y cruzipaína en cepas colombianas de Trypanosoma cruzi

Biomédica: revista del Instituto Nacional de Salud, 2007
Introducción. Los estudios genéticos en Trypanosoma cruzi han buscado establecer asociaciones de variantes genéticas del parásito con manifestaciones clínicas de la enfermedad, origen biológico y geográfico de los aislamientos; sin embargo, los ...
Winston Rojas, Maria Antonieta Caro, Juan Guillermo Lopera, Omar Triana, Juan Carlos Dib, Gabriel Bedoya   +5 more
doaj   +1 more source

A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints

Advanced Science, EarlyView.
ARESEC is a synthetic platform that reconstructs functional V(D)J recombination in HEK293T cells. By introducing RSS elements and co‐expressing RAG1/2 and TdT across all three antibody CDRs, it enables programmable junctional diversification and direct generation of high‐affinity variants targeting PD‐1/PD‐L1, overcoming the evolutionary constraints of
Wang Liu, Jun Yang, Yuhang Zhang, Xiaoli Xue   +3 more
wiley   +1 more source

Molecular identification and typing of campylobacter concisus [PDF]

, 2000
Bibliography: leaves 103 ...
Matsheka, Maitshwarelo Ignatius
core   +1 more source

Polymerase chain reaction–restriction fragment length polymorphism (PCR-RFLP) agarose gel electrophoresis patterns of IL-8 polymorphisms.

, 2022
Polymerase chain reaction–restriction fragment length polymorphism (PCR-RFLP) agarose gel electrophoresis patterns of IL-8 polymorphisms.
Jin Won Kim (224828), Jin-Soo Kim (7954), Jin Hyun Park (3035565), Ji-Won Kim (174475), Keun-Wook Lee (403308), In Sil Choi (5349383), Mi Young Kim (1544923)   +6 more
core   +1 more source

THSD7A Exacerbates Atherosclerosis via Activation of Signaling Axis αvβ3/CEBPD/IL1A

Advanced Science, EarlyView.
THSD7A exerts pro‐inflammatory effects and exacerbates atherosclerosis. Mechanistically, THSD7A regulates endothelial cell inflammation and atherosclerosis by activating the αvβ3/CEBPD/IL1A signaling axis. THSD7A is not only a genetic marker but also a potential therapeutic target for coronary artery disease (CAD).
Jiankun Liu, Hongfei Liu, Yiqi Wan, Andong Wu, Jiayu Qiu, Xueting Gong, Ya Zhao, Yuanyuan Li, Bingbing Zhou, Yangyi Zheng, Fang Wu, Yuanzheng Zhu, Weixin Lv, Xueer Li, Qiang Yuan, Xiao‐Li Tian   +15 more
wiley   +1 more source