Results 81 to 90 of about 2,919,054 (308)

A Living Multi‐Omics PDX Biobank of High‐Risk Sarcomas Reveals ecDNA‐Driven Oncogene Amplification in Osteosarcoma and Enables Preclinical Precision Oncology

Advanced Science, EarlyView.
A living multi‐omics sarcoma PDX biobank is enriched for high‐risk disease and preserves key patient tumor features at histopathological and molecular levels. Integrated profiling reveals ecDNA‐driven oncogene amplification in osteosarcoma and preferential retention of ecDNA during PDX evolution.
Weisong Zhao, Zhiwei Cheng, Kai Tian, Mengxiong Sun, Zhuoying Wang, Ming Jiao, Jens Luebeck, Kaiyuan Zhu, Xiao Zhang, Dongqing Zuo, Hongsheng Wang, Chongren Wang, Jiakang Shen, Xiaojun Ma, Gangyang Wang, Zongyi Wang, Jing Han, Kaiyuan Liu, Haoran Mu, Weiqi Ma, Yongyong Ren, Shibing Guo, Huangxin Tu, Lingfeng Yu, Yining Tao, Yu Lv, Hui Lu, Owen S. Chapman, Rishaan Kenkre, Lukas Chavez, Zhengdong Cai, Yuqin Yang, Wei Sun, Yafei Jiang, Yingqi Hua   +34 more
wiley   +1 more source

PENGGUNAAN TEKNIK PCR DAN RFLP UNTUK DETEKSI DAN ANALISIS KERAGAMAN VIRUS GEMINI PADA TANAMAN TOMAT YANG BERASAL DARI BERBAGAI DAERAH DI JAWA BARAT DAN LAMPUNG

Jurnal Hama dan Penyakit Tumbuhan Tropika, 2012
The Technique of PCR and RFLP to detection and analysis geminivirus diversity on tomato from growing areas in West Java and Lampung. Geminivirus infection has been reported on various important crops, among others on tomato. Infected plant were collected
Sudiono , Sri Hendrastuti Hidayat, , Rusmilah Suseno2, dan Soemartono Sosromarsono
doaj   +1 more source

Rapid Communication: An XbaI Restriction Fragment Length Polymorphism at the Porcine T-Complex 1 (TCP1) Locus [PDF]

, 1994
Polymorphism. A restriction fragment length polymorphism (RFLP) was detected in the swine TCPl locus using the restriction enzyme XbaI. Source and Description of Clone.
Warner, Carol, Vaske, D. A., Rahman, A., Larson, R. G., Rothschild, Max   +4 more
core  

AKAP1 Protects Retinal Ganglion Cells and Preserves Vision by Improving Mitochondrial and Synaptic Health in Glaucomatous Neurodegeneration

Advanced Science, EarlyView.
Intravitreal AAV2‐mediated AKAP1 restoration enhances mitochondrial fusion and biogenesis, improves bioenergetic capacity, and preserves mitochondrial integrity in glaucomatous RGCs. AKAP1 stabilizes presynaptic structure, maintaining synaptic protein expression, and limiting complement‐associated neuroinflammation.
Tonking Bastola, Keun‐Young Kim, Ziyao Shen, Guy A. Perkins, Muna Poudel, Yoonjin Lim, Hyejeong Choi, Soo‐Ho Choi, Mark H. Ellisman, Robert N. Weinreb, Won‐Kyu Ju   +10 more
wiley   +1 more source

Molecular techniques for the study and diagnosis of parasite infection

Journal of Venomous Animals and Toxins including Tropical Diseases, 2011
In parasitology, routine laboratory diagnosis involves conventional methods, such as optical microscopy, used for the morphological identification of parasites. Currently, molecular biology techniques are increasingly used to diagnose parasite structures
RG Tavares, R Staggemeier, ALP Borges, MT Rodrigues, LA Castelan, J Vasconcelos, ME Anschau, SM Spalding   +7 more
doaj   +1 more source

BamHI restriction fragment length polymorphism (RFLP) at the human GST3 gene locus

, 1994
A new restriction fragment length polymorphism (RFLP) detected for the human glutathione S-transferase-pi (GST3) gene with the restriction endonuclease,BamHI (GGATCC) is described.
Sharma, J. K., Kumar, Ajay, Das, B. C.
core   +1 more source

Discrimination between Bifidobacterium species from human and animal origin by PCR-restriction fragment length polymorphism [PDF]

, 2004
peer reviewedBifidobacteria are normal intestinal flora in humans and animals. The genus Bifidobacterium includes 31 species of significant host specificity.
N. Bechoux, Bechoux, Nathalie, Leonard, Tamara, Daube, Georges, Delcenserie, Véronique, T. Leonard, China, Bernard, B. China, G. Daube, V. Delcenserie   +9 more
core   +1 more source

Gapless Complete Genome and Multi‐Omics Illuminate Immune Adaptation and Host‐Virus Interactions in a Coronavirus Reservoir

Advanced Science, EarlyView.
We present a complete T2T genome assembly for a key bat reservoir. Integrating population genomics, comparative genomics, transcriptomics, single‐cell omics, and functional assays, we resolve previously inaccessible genomic regions and identify evolutionary signatures associated with immune adaptation.
Yuting Wang, Sheng Zhang, Linxia Ouyang, Xin Du, Xin Huang, Zhilin Wang, Huixian Xie, Jiale Tang, Liyi Lou, Wenqing Ling, Weihao Wang, Jiang Zhou, Zhen Liu, Yibo Hu, Fuwen Wei, Guangping Huang   +15 more
wiley   +1 more source

Supramolecular Assembly of an Antimicrobial Peptide Into a Pore

Angewandte Chemie, EarlyView.
Supramolecular assembly of an AMP is linked to transport across the Staphylococcus aureus membrane. ABSTRACT Antimicrobial peptides (AMPs) have long been ascribed the ability to form pores. These structures, some observed, others inferred, vary in their mechanisms of action, though most are associated with lysis.
Kathyana Deeyagahage, Poonam Dhindwal, Michal T. Boniecki, Antonio Ruzzini   +3 more
wiley   +2 more sources

An integrated restriction fragment length polymorphism - amplified fragment length polymorphism linkage map for cultivated sunflower

, 2001
Restriction fragment length polymorphism (RFLP) maps have been constructed for cultivated sunflower (Helianthus annuus L.) using three independent sets of RFLP probes. The aim of this research was to integrate RFLP markers from two sets with RFLP markers
Johan Peleman, Crispin Wye, Bart Segers, Alberto Leon, Mary B Slabaugh, Steven J Knapp, Simon Berry, Melaku Ayele Gedil, Richard Jones   +8 more
core   +1 more source