Results 71 to 80 of about 1,185,484 (304)

Association between the frequency of daily intellectual activities and cognitive domains: A cross‐sectional study in older adults with complaints of forgetfulness

Brain and Behavior, 2021
Objectives Frequent engagement in intellectual activities has been shown to reduce the risk of developing dementia. The present study sought to examine the association between the frequency of daily intellectual activities and cognitive domains in older ...
Ai Iizuka, Hiroyuki Suzuki, Susumu Ogawa, Tomoya Takahashi, Sachiko Murayama, Momoko Kobayashi, Yoshinori Fujiwara   +6 more
doaj   +1 more source

Development of a Step Counting Algorithm Using the Ambulatory Tibia Load Analysis System for Tibia Fracture Patients [PDF]

, 2018
Introduction: Ambulation can be used to monitor the healing of lower extremity fractures. However, the ambulatory behavior of tibia fracture patients remains unknown due to an inability to continuously quantify ambulation outside of the clinic.
Ackerman, Matt, Hitchcock, Robert, Kubiak, Erik, Lajevardi-Khosh, Arad, Petelenz, Tomasz, Sinclair, Sarina, Stuart, Ami, Tresco, Ben   +7 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Problems of management of rights to the results of intellectual activity created using budget funds

Ekonomika Nauki, 2019
The article analyzes the problems arising from the commercialization of scientific results obtained using budgetary funds, due to the unresolved number of fundamental issues of managing the rights to such results of intellectual activity.
D. P. Fedulkin, V. G. Zinov
doaj   +1 more source

Inventors and pirates: Creative activity and intellectual property rights [PDF]

, 2001
This paper analyzes a model in which creative activity and the security of intellectual property rights are jointly determined, both depending on the choices made by potentially creative people either to engage in creative activity or to be pirates of ...
Grossman, Herschel I.
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Investment activity in intellectual property objects and their use elementary assessment in the company’s activities

Ученые записки Российской академии предпринимательства
The article examines the current trends of investment activity in intellectual property objects. The criteria for recognizing the results of intellectual activity as part of the intangible assets of the enterprise are defined.
S. A. Polukhina, E. A. Nikiforova
doaj   +1 more source

Effective methods of protection of the intellectual activity results in infosphere of global telematics networks

Открытое образование (Москва), 2016
The purpose of this article is perfection of using metodology of technological and organization and legal protect of intellectual activity results and related intellectual rights in information sphere of Global Telematics Networks (such as of «Internet»,
D. A. Lovtsov
doaj   +1 more source

[Commercialization of results of intellectual activities in pharmaceutical industry].

Likars'ka sprava, 2003
An analysis has been done of those causes impending the development of innovative processes and commercialization of results of intellectual activities in the economics of Ukraine and its pharmaceutical sector. Possible ways for rectifying the prevailing situation are considered.
O V, Posylkina, V N, Timaniuk, E V, Gladukh   +2 more
openaire   +1 more source

Process of intellectual property management [PDF]

, 2012
Стаття присвячена дослідженню процесу управління інтелектуальною власністю на промисловому підприємстві. Проаналізовано процес зміни об’єкта управління, сформульовано критерії оцінки ефективності стратегічного та оперативного управління інтелектуальною ...
Павленко, Т. В.
core