Results 71 to 80 of about 259,600 (261)
GENESIS OF LEGAL REGULATION OF THE DESIGN OF THE RESULTS OF INTELLECTUAL ACTIVITIES
Social Law, 2019 The article analyzes the legal regulation of the formation of the results of intellectual activity, therelationship of history with modern realities. The periodization of the process of development of legalintellectual activity of a person is determined, and important factors that influenced the formation anddevelopment of this sphere of ...
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Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Students’ intellectual culture: diagnostics OF development level
Вестник Тамбовского университета. Серия: Гуманитарные науки, 2018 The diagnostical stage results of the research of the university students’ intellectual culture formedness are presented. The research with 126 respondents was carried out on the base of Tambov State University named after G.R. Derzhavin. The analysis of
D. V. Mitrofanov
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Journal of Physics: Conference Series, 2016 Developing (underdeveloped) countries are territories of slow economic growth (catch-up growth). Perspectives of their economic growth largely depend on developing and introducing financial and technological innovations in the sphere of the financial markets.
Shkolik, Oleg +2 more
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Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Сибирское юридическое обозрение, 2015 The article is devoted to changes in the legal regulation of intellectual property dating from October 1, 2014. The article reveals the peculiarities of disposal of exclusive right to results of intellectual activity and means of individualization ...
N. A. Permyakova
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University as a social corporation: Problems of legal nature
Ученые записки Казанского университета: Серия Гуманитарные науки, 2018 Nowadays, the transformation of universities as the main subjects of innovative economy takes place. The university should become part of an innovative, entrepreneurial system.
O.A. Serova
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