Resveratrol Alleviates Intervertebral Disc Degeneration by Targeting NCOA4-Mediated Ferritinophagy Through Dual Antioxidant and Anti-Inflammatory Effects. [PDF]
Song C +8 more
europepmc +1 more source
Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali +4 more
wiley +1 more source
Natural Polyphenols Versus Standard Therapy: Effects on Neuroinflammation and Alpha-Synuclein Expression in a 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Induced Mouse Model of Parkinson's Disease. [PDF]
Singh S +7 more
europepmc +1 more source
Constructing Neuroinflammation‐On‐A‐Chip for Traditional Chinese Medicine Extracts Evaluation
We present a biomimetic neuroinflammation‐on‐a‐chip that models inflammatory microenvironments for efficient drug evaluation. This platform allows high‐throughput, dose‐dependent screening of natural compounds, offering a reliable tool for discovering anti‐neuroinflammatory therapeutics.
Xirui Wang +5 more
wiley +1 more source
Experimental and Modeling Assessment of Polyphenol Solubility in Alcohol + Ethyl Acetate Mixtures for Extraction Applications. [PDF]
Montenegro I +3 more
europepmc +1 more source
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang +18 more
wiley +1 more source
Silk fibroin-coated resveratrol solid lipid nanoparticles for diabetic wound healing. [PDF]
Bogadi S +8 more
europepmc +1 more source
ABSTRACT Skeletal system diseases, encompassing chronic disorders of the skeletal system which commonly include osteoarthritis, rheumatoid arthritis, osteoporosis and osteosarcoma. Their incidence rates have been increasing in recent years, resulting in significant social and economic burdens.
Qian Yi +8 more
wiley +1 more source
The Multidirectional Biological Activity of Resveratrol: Molecular Mechanisms, Systemic Effects and Therapeutic Potential-A Review. [PDF]
Kogut Ł +3 more
europepmc +1 more source

