Results 31 to 40 of about 132,275 (287)

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

open access: yesHepatology, EarlyView., 2022
NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger   +7 more
wiley   +1 more source

Resveratrol Targets Sphingolipid Metabolism and BCR-ABL in Ph+ Acute Lymphoblastic Leukemia to Induce Growth Inhibiton

open access: yesProceedings, 2019
The mechanisms underlying the growth inhibitory effect of resveratrol on Ph+ ALL cells were investigated with regard to targeting of ceramide metabolism and changes in BCR-ABL expression.
Osman Oğuz, Aysun Adan
doaj   +1 more source

Biological function of resveratrol and its application in animal production: a review

open access: yesJournal of Animal Science and Biotechnology, 2023
With the prohibition of antibiotics in feed, plant functional substances have been widely studied as feed additives. Resveratrol, a natural stilbene, and a non-flavonoid polyphenol found in plants, possesses antioxidant, anti-inflammatory, and metabolic ...
Qingwei Meng   +3 more
doaj   +1 more source

Resveratrol and Malignancies [PDF]

open access: yesCurrent Pharmacology Reports, 2015
Carcinogenesis is a multifactorial process, frequently encompassing 3 stages: initiation, promotion and progression. It is characterized by multiple deviations from normal both at the cell and organism levels. Although most people have a small number of cells that present deviations from normal, most of those cells will not cause cancer.
Rodica P, Bunaciu, Andrew, Yen
openaire   +2 more sources

Polyphenols as Suitable control for Obesity and Diabetes [PDF]

open access: yes, 2018
Modern life is characterized by physical inactivity and poor food choices, which is often a prerequisite for unhealthy weight gain and overweight/obesity.
Alexieva, Iordanka   +4 more
core   +1 more source

Resveratrol inhibits the growth of gastric cancer by inducing G1 phase arrest and senescence in a Sirt1-dependent manner. [PDF]

open access: yesPLoS ONE, 2013
Resveratrol, a naturally occurring polyphenolic compound, has been reported to exert anticancer activity by affecting diverse molecular targets. In this study, we examined the effects and the underlying mechanisms of resveratrol on gastric cancer.
Qing Yang   +6 more
doaj   +1 more source

Modulation of PGC-1α activity as a treatment for metabolic and muscle-related diseases [PDF]

open access: yes, 2014
Physical inactivity is a predisposing factor for various disease states including obesity, cardiovascular disease, as well as for certain types of cancer. Regular endurance exercise mediates several beneficial effects such as increased energy expenditure
Handschin, Christoph   +1 more
core   +1 more source

Treatment strategies for high resveratrol induction in Vitis vinifera L. cell suspension culture

open access: yesBiotechnology Reports, 2014
Bioprocesses capable of producing large scales of resveratrol at nutraceutical grade are in demand. This study herein investigated treatment strategies to induce the production of resveratrol in Vitis vinifera L. cell suspension cultures.
Thu V. Vuong, Chris Franco, Wei Zhang
doaj   +1 more source

Rescued chlorhexidine activity by resveratrol against carbapenem-resistant Acinetobacter baumannii via down-regulation of AdeB efflux pump.

open access: yesPLoS ONE, 2020
The aim of this study was to determine the activity and synergistic mechanisms of resveratrol in combination with chlorhexidine against carbapenem-resistant Acinetobacter baumannii clinical isolates.
Uthaibhorn Singkham-In   +4 more
doaj   +1 more source

Resveratrol Inhibits CD4+ T cell activation by enhancing the expression and activity of Sirt1. [PDF]

open access: yesPLoS ONE, 2013
Resveratrol, a natural polyphenol compound, has broad effects on critical events, including inflammation, oxidation, cancer and aging. However, the function and molecular mechanisms of resveratrol on T cell activation are controversial.
Ting Zou   +7 more
doaj   +1 more source

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