Results 51 to 60 of about 153,036 (290)

Oxidative stress: new insights on the association of nonalcoholic fatty liver disease and atherosclerosis [PDF]

, 2015
Non-alcoholic fatty liver disease (NAFLD) represents the most common and emerging chronic liver disease worldwide. It includes a wide spectrum of liver diseases ranging from simple fatty liver to non-alcoholic steatohepatitis (NASH), which may progress ...
Albanese, Fabiana, Angelico, Francesco, Baratta, Francesco, DEL BEN, Maria, Pastori, Daniele, Perri, Ludovica, Polimeni, Licia, Violi, Francesco   +7 more
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Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Hybrid Nanofibers for Multimodal Accelerated Wound Healing

Advanced Healthcare Materials, EarlyView.
Fabrication of wound healing scaffolds based on biocompatible nanofibers. Nanofibers offering high surface area, flexibility, and biocompatibility significantly improved the healing outcome in vivo. Histological, immunological, and anti‐inflammatory markers are noticeably better in treated wounds.
Viraj P. Nirwan, Bence Bajusz, Norbert Fabók, Marina Rudan Dimlic, Jelena Budimir, Tshepang Mqatywa, Miklós Gyöngy, Márton Ferencz, Dorottya Kocsis, Olexandr Bondarenko, Mariia Rolduhina, Milena Lengyel, Istvan Antal, Rebecca Hengsbach, Franciska Erdő, Amir Fahmi   +15 more
wiley   +1 more source

Resveratrol improves ex vivo mitochondrial function but does not affect insulin sensitivity or brown adipose tissue in first degree relatives of patients with type 2 diabetes

Molecular Metabolism, 2018
Objective: Resveratrol supplementation improves metabolic health in healthy obese men, but not in patients with type 2 diabetes (T2D) when given as add-on therapy.
Marlies de Ligt, Yvonne M.H. Bruls, Jan Hansen, Marie-Fleur Habets, Bas Havekes, Emmani B.M. Nascimento, Esther Moonen-Kornips, Gert Schaart, Vera B. Schrauwen-Hinderling, Wouter van Marken Lichtenbelt, Patrick Schrauwen   +10 more
doaj   +1 more source

Effect of DNA repair deficiencies on the cytotoxicity of resveratrol [PDF]

, 2015
Numerous preclinical studies have shown that the naturally-occurring polyphenol resveratrol may produce health-beneficial effects in a variety of disorders, including cancer, diabetes, Alzheimer, and cardiovascular diseases.
Burgos Morón, Estefanía, Calderón Montaño, José Manuel, López Lázaro, Miguel, López Lázaro, Miguel (Coordinador), Mateos Cordero, Santiago, Orta Vázquez, Manuel Luis   +5 more
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Evaluation of Hungarian Wines for Resveratrol by Overpressured Layer Chromatography [PDF]

, 2013
A method, including solid phase extraction sample preparation, overpressured layer chromatographic separation and subsequent densitometric evaluation, was developed for measurement of total resveratrol (cis- and trans-isomers) content of wine. The amount
Airado-Rodriguez D., Arce L., Baptista J.A.B., Bavaresco L., Botz L., Boutegrabet L., Chen M., Creasy L.L., Dixon R.A., Dominguez C., Dugo G., Esna-Ashari M., Goldberg D.M., Goldberg D.M., Goldberg D.M., György Kátay, Hakimuddin F., Ingham J.L., Jaitz L., Jean-Denis J.B., Jeandet P., Jeandet P., Kerem Z., Király-Véghely Zs., Király-Véghely Zs., Klára Otta, Kolouchová-Hanzlíková I., Mahady G.B., Mark L., Martinez J., Mattivi F., McMurtrey K.D., Mercolini L., Mincsovics E., Mincsovics E., Mincsovics E., Nicolaou I.N., Paulo L., Pekec B., Peng Y.Y., Peres R.G., Pezet R., Pineiro Z., Porgali E., Quiros A.R.B., Renaud S., Rodler I., Rodríguez-Bernaldo de Quirós A., Romero-Perez A.I., Schmandke H., Siemann E.H., Siouffi A.M., Soleas G.J., Stark T., Tarola A.M., Tyihák E., Uenobe F., Vitrac X., Waddington E., Waterhouse A.L., Zotou A., Zsuzsa Király-Véghely, Ágnes Móricz   +62 more
core   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source

Resveratrol eliminates cancer stem cells of osteosarcoma by STAT3 pathway inhibition. [PDF]

PLoS ONE, 2018
Resveratrol shows potent anti-tumor therapeutic properties in various tumors. However, the exact effect of resveratrol on osteosarcoma cells, especially cancer stem cells, remains unclear.
Lihua Peng, Dianming Jiang
doaj   +1 more source

Comprehensive Investigation of Stereoselective Food Drug Interaction Potential of Resveratrol on Nine P450 and Six UGT Isoforms in Human Liver Microsomes

Pharmaceutics, 2021
The stereoselectivity of the food drug inhibition potential of resveratrol on cytochrome P450s and uridine 5′-diphosphoglucuronosyl transferases was investigated in human liver microsomes.
Seung-Bae Ji, So-Young Park, Subin Bae, Hyung-Ju Seo, Sin-Eun Kim, Gyung-Min Lee, Zhexue Wu, Kwang-Hyeon Liu   +7 more
doaj   +1 more source

ISOLATION AND IDENTIFICATION STRUCTURE OF RESVERATROL AND THEIR ACTIVITY TEST AS ANTIOXIDANT AND UV-B PROTECTION FROM STEM BARK OF MELINJO (GNETUM GNEMON) [PDF]

, 2006
Resveratrol (1) had been isolated from the stem bark of melinjo (Gnetum gnemon). The structure of this compound were elucidated based on physical and spectroscopic data (UV, IR, 1H and 13C NMR).
Sri Atun, Ph.D.
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