Results 41 to 50 of about 1,137 (129)
Ophthalmic and Physiological Optics, Volume 42, Issue 4, Page 814-827, July 2022., 2022 Abstract Purpose Age‐related macular degeneration (AMD) is a leading cause of vision impairment. This randomised placebo‐controlled trial investigated whether point‐of‐care tools can improve optometrists' AMD knowledge and/or care provision. Methods Australian optometrists (n = 31) completed a demographics survey and theoretical AMD case study multiple‐
Sena A Gocuk +2 more
wiley +1 more source
Subretinal drusenoid deposits: An update
Taiwan Journal of Ophthalmology, 2022 A wide spectrum of phenotypic manifestations characterizes age-related macular degeneration (AMD). Drusen is considered the hallmark of AMD and is located underneath the retinal pigment epithelium (RPE). In contrast, subretinal drusenoid deposits (SDDs),
Manuel Monge, Adriana Araya, Lihteh Wu
doaj +1 more source
Prevalence and phenotype associations of complement factor I mutations in geographic atrophy
Human Mutation, Volume 42, Issue 9, Page 1139-1152, September 2021., 2021 This study demonstrates, for the first time, the prevalence of disease‐causing complement factor I (CFI) gene mutations in an unselected cohort of patients with geographic atrophy secondary to age‐related macular degeneration. Reticular pseudodrusen was detected in all patients with a rare CFI gene variant in this study.
Adnan H. Khan +19 more
wiley +1 more source
Acta Ophthalmologica, Volume 99, Issue 3, Page e402-e414, May 2021., 2021 Abstract Purpose To investigate the retinal structure and function in patients with CRB1‐associated retinal dystrophies (RD) and to explore potential clinical endpoints. Methods In this prospective cross‐sectional study, 22 patients with genetically confirmed CRB1‐RD (aged 6–74 years), and who had a decimal best‐corrected visual acuity (BCVA) ≥ 0.05 at
Mays Talib +14 more
wiley +1 more source
Photonics, 2023 Artificial intelligence (AI) represents a growing and promising branch of computer science that is expanding the horizon of prediction, screening, and disease monitoring.
Serena Fragiotta +2 more
doaj +1 more source
Extensive Macular Atrophy with Pseudodrusen Imaged with OCT Angiography
Case Reports in Ophthalmological Medicine, 2018 This report describes the first case of extensive macular atrophy with pseudodrusen (EMAP) imaged with optical coherence tomography angiography (OCTA). A 58-year-old Caucasian man presented with decreased central vision in both eyes.
Jaclyn L. Kovach
doaj +1 more source
Ophthalmology Science, 2022 Purpose: To evaluate visual function (VF) changes in early and intermediate age-related macular degeneration (eAMD and iAMD) over 24 months. Design: Prospective, observational natural history study.
Eleonora M. Lad, MD, PhD +6 more
doaj +1 more source
Retinal phenotyping of variants of Alzheimer's disease using ultra‐widefield retinal images
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021 Background Posterior cortical atrophy (PCA) is the most common atypical variant of Alzheimer's disease (AD). Changes associated with PCA in the brain affect the visual cortex, but little is known about retinal changes in PCA.
Lajos Csincsik +5 more
doaj +1 more source
CellsAdaptive optics transscleral flood illumination (AO-TFI) enables in vivo imaging of the retinal pigment epithelium (RPE) at near-cellular resolution. In this study, we evaluated its potential as a phenotyping tool in age-related macular degeneration (AMD)
Safa Mohanna +8 more
doaj +1 more source
Deep Learning‐Based Detection of Reticular Pseudodrusen in Age‐Related Macular Degeneration
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Background Reticular pseudodrusen (RPD) signify a critical phenotype driving vision loss in age‐related macular degeneration (AMD). This study sought to develop and externally test a deep learning (DL) model to detect RPD on optical coherence tomography (OCT) scans with expert‐level performance.
Himeesh Kumar +26 more
wiley +1 more source