Results 81 to 90 of about 40,038 (240)

Implementing Predictive Models in Artificial Intelligence through OCT Biomarkers for Age-Related Macular Degeneration

Photonics, 2023
Artificial intelligence (AI) represents a growing and promising branch of computer science that is expanding the horizon of prediction, screening, and disease monitoring.
Serena Fragiotta, Flaminia Grassi, Solmaz Abdolrahimzadeh   +2 more
doaj   +1 more source

Inner Retinal Layer Thickness Alterations in Early Age Related Macular Degeneration in Eyes with Subretinal Drusenoid Deposits or Conventional Drusen [PDF]

, 2021
The purpose of this study was to evaluate central and parafoveal inner retinal layer thickness in patients with subretinal drusenoid deposits (SDD) or conventional drusen (CD). Participants underwent comprehensive ophthalmoscopic examination. Evidence of
Abdolrahimzadeh, Solmaz, Di Pippo, Mariachiara, Sordi, Edoardo, Zweifel, Sandrine Anne   +3 more
core   +1 more source

Longitudinal Analysis of Structural and Functional Changes in Presence of Reticular Pseudodrusen Associated With Age-Related Macular Degeneration. [PDF]

Invest Ophthalmol Vis Sci, 2020
Purpose To examine longitudinal changes of retinal thickness and retinal sensitivity in patients with intermediate age-related macular degeneration (iAMD) and predominantly reticular pseudodrusen (RPD).
Sassmannshausen M, Pfau M, Thiele S, Fimmers R, Steinberg JS, Fleckenstein M, Holz FG, Schmitz-Valckenberg S.   +7 more
europepmc   +2 more sources

Choroidal Changes Associated with Reticular Pseudodrusen

Investigative Opthalmology & Visual Science, 2012
To analyze choroidal changes associated with reticular pseudodrusen by indocyanine green angiography (ICGA) and enhanced depth imaging spectral-domain optical coherence tomography (EDI SD-OCT).Twenty-two consecutive patients (22 eyes) with reticular pseudodrusen, and without medium/large drusen, underwent ICGA and EDI OCT.
Nathalie Massamba, Eric H Souied, Raimondo Forte, Florence Coscas, Giuseppe Querques, Giuseppe Querques, Lea Querques, Lea Querques   +7 more
openaire   +6 more sources

Quantitative proteomic analysis of aqueous humor from patients with drusen and reticular pseudodrusen in age-related macular degeneration. [PDF]

BMC Ophthalmol, 2018
Background To identify novel biomarkers related to the pathogenesis of dry age-related macular degeneration (AMD), we adopted a human retinal pigment epithelial (RPE) cell culture model that mimics some features of dry AMD including the accumulation of ...
Baek JH, Lim D, Park KH, Chae JB, Jang H, Lee J, Chung H.   +6 more
europepmc   +2 more sources

An Evaluation of a Battery of Functional and Structural Tests as Predictors of Likely Risk of Progression of Age-Related Macular Degeneration. [PDF]

, 2018
Purpose: To evaluate the ability of visual function and structural tests to identify the likely risk of progression from early/intermediate to advanced AMD, using the Age-Related Eye Disease Study (AREDS) simplified scale as a surrogate for risk of ...
Bailey, C., Binns, A. M., Margrain, T. H., Robinson, D. G.   +3 more
core   +3 more sources

Multifocal Electroretinography in Eyes with Reticular Pseudodrusen

Investigative Opthalmology & Visual Science, 2012
The aim of our study was to evaluate the impact of reticular pseudodrusen (RPD) on retinal function by multifocal electroretinography (mfERG), and combined simultaneous confocal scanning laser ophthalmoscopy (cSLO) and spectral-domain optical coherence tomography (SD-OCT).We included 19 eyes of 15 patients with RPD in the posterior pole and no other ...
Christoph R. Clemens, Peter Heiduschka, Nicole Eter, Florian Alten   +3 more
openaire   +3 more sources

Extensive Macular Atrophy with Pseudodrusen Imaged with OCT Angiography

Case Reports in Ophthalmological Medicine, 2018
This report describes the first case of extensive macular atrophy with pseudodrusen (EMAP) imaged with optical coherence tomography angiography (OCTA). A 58-year-old Caucasian man presented with decreased central vision in both eyes.
Jaclyn L. Kovach
doaj   +1 more source

The role of optical coherence tomography angiography in reticular pseudodrusen

Photodiagnosis and Photodynamic Therapy, 2021
To investigate the changes in retinal and choriocapillaris vessel density (VD) in patients effected by early age-related macular degeneration (AMD) and reticular pseudodrusen (RPD), using Optical Coherence Tomography Angiography (OCTA).A total of seventy-eight eyes of 78 patients (43 male, 35 female, mean age 72.61 ± 5.15) with non-neovascular AMD (38 ...
Montorio D., D'Andrea L., Mirto N., Cennamo G.   +3 more
openaire   +4 more sources

Retinal pigment epithelium and age‐related macular degeneration: A review of major disease mechanisms

Clinical &Experimental Ophthalmology, Volume 48, Issue 8, Page 1043-1056, November 2020., 2020
Abstract Age‐related macular degeneration (AMD) is a progressive degenerative disease that is the leading cause of vision loss in the elderly population. Degeneration/dysregulation of the retinal pigment epithelium (RPE), a supportive monolayer of cells underlying the photoreceptors, is commonly seen in patients with AMD. While treatment exists for the
Shreya Somasundaran, Ian J. Constable, Carla B. Mellough, Livia S. Carvalho   +3 more
wiley   +1 more source