Results 31 to 40 of about 93,775 (268)

Platelet Subtypes in Inflammatory Settings

Frontiers in Cardiovascular Medicine, 2022
In addition to their essential role in hemostasis and thrombosis, platelets also modulate inflammatory reactions and immune responses. This is achieved by specialized surface receptors as well as secretory products including inflammatory mediators and ...
Muataz Ali Hamad, Muataz Ali Hamad, Muataz Ali Hamad, Krystin Krauel, Krystin Krauel, Nancy Schanze, Nancy Schanze, Nadine Gauchel, Peter Stachon, Thomas Nuehrenberg, Mark Zurek, Daniel Duerschmied, Daniel Duerschmied, Daniel Duerschmied   +13 more
doaj   +1 more source

Diagnostics of thrombocytopenias [PDF]

Терапевтический архив, 2018
Laboratory methods used for the diagnostics of thrombocytopenias are reviewed. Differential diagnosis is usually carried out between immune and hypoproductive forms of thrombocytopenia.
A V Mazurov, S G Khaspekova, S A Vasiliev   +2 more
doaj   +1 more source

Reference Intervals of Reticulated Platelets and Other Platelet Parameters and Their Associations [PDF]

Archives of Pathology and Laboratory Medicine, 2013
Context. —Reticulated platelets are platelets recently released from the bone marrow, and they can serve as a noninvasive indicator of recent megakaryopoietic activity. Widespread clinical use has been hampered by laborious methods and lack of standardization.
Johannes J M L, Hoffmann, Nicole M A, van den Broek, Joyce, Curvers   +2 more
openaire   +2 more sources

What can we learn from senescent platelets, their transcriptomes and proteomes?

Platelets, 2023
Research into the natural aging process of platelets has garnered much research interest in recent years, and there have long been associations drawn between the proportion of newly formed platelets in the circulation and the risk of thrombosis. However,
Harriet E. Allan, Ami Vadgama, Paul C. Armstrong, Timothy D. Warner   +3 more
doaj   +1 more source

Mitochondrial gene expression is required for platelet function and blood clotting

Cell Reports, 2023
Summary: Platelets are anucleate blood cells that contain mitochondria and regulate blood clotting in response to injury. Mitochondria contain their own gene expression machinery that relies on nuclear-encoded factors for the biogenesis of the oxidative ...
Tara R. Richman, Judith A. Ermer, Jessica Baker, Stefan J. Siira, Benjamin T. Kile, Matthew D. Linden, Oliver Rackham, Aleksandra Filipovska   +7 more
doaj   +1 more source

The Role of Immature Platelet Fraction and Reticulated Platelets in Stroke Monitoring and Outcome Prognosis: A Systematic Review. [PDF]

J Clin Med
Background/Objectives: Immature platelet fraction (IPF) and reticulated platelets (RPs) are biomarkers reflecting the youngest and most metabolically active platelets in circulation. RPs, a subset of immature platelets, contain residual RNA and have been
Tsankof A, Tsakiris DA, Skoura L, Tsiatsiou P, Ztriva E, Ntaios G, Savopoulos C, Kaiafa G.   +7 more
europepmc   +2 more sources

Reticulated platelets

Platelets, 1997
Young or reticulated platelets contain some residual mRNA, which is rapidly degraded after platelet release into the circulation. They can be easily detected either with supravital dye staining (e.g. new methylene blue) on blood films, or more commonly with fluorescent dyes (e.g thiazole orange) and flow cytometry.
P, Harrison, M S, Robinson, I J, Mackie, S J, Machin   +3 more
openaire   +2 more sources

P222 | RETICULATED PLATELETS CONTRIBUTION TO TISSUE FACTOR AND TRANSFORMING GROWTH FACTOR-BETA GENERATION IN PRIMARY MYELOFIBROSIS

Haematologica
In Primary Myelifibrosis (PMF) the platelets contribute to the vascular complication and fibrosis. We focused on the reticulated immature platelets as in PMF there is an increased platelet turnover. It also is reported that the reticulated platelets (RPs)
V. Vecchio, R. Cacciola, E. Cacciola.
doaj   +1 more source

Ultrastructural, transcriptional, and functional differences between human reticulated and non‐reticulated platelets [PDF]

Journal of Thrombosis and Haemostasis, 2020
Reticulated platelets (RP) are the youngest circulating platelets in blood. An increased amount of this subpopulation is associated with higher cardiovascular risk and mortality.It is unknown to what extent intrinsic properties of RP contribute to their hyperreactive features.
Laura Hille, Maximilian Lenz, Andreas Vlachos, Björn Grüning, Lutz Hein, Franz‐Josef Neumann, Thomas G. Nührenberg, Dietmar Trenk   +7 more
openaire   +3 more sources

Unveiling Thrombocytopenic Disorders: The Role of Reticulated Platelets [PDF]

Zagazig University Medical Journal
Background: Thrombocytopenic disorders are a wide-ranging group of diseases and ailments that cause a decrease in platelet count. Diagnosing these disorders can be difficult because they often have similar symptoms and causes.
Hisham Omar, Monkez Yousif, Nahla Zidan, Mohamad Ghareeb   +3 more
doaj   +1 more source