Results 51 to 60 of about 93,775 (268)

Assessment of reticulated platelets with automated hemocytometers: are we measuring the same thing?

, 2016
Assessment of reticulated platelets with automated hemocytometers: are we measuring the same ...
Dima, Francesco, Hoffmann, Johannes J. M. L., Montolli, Valentina, LIPPI, Giuseppe   +3 more
core   +1 more source

Application of new parameters of platelets (CD61 and reticulated platelets) in laboratory monitoring trombocytopenia [PDF]

Halo 194, 2018
INTRODUCTION. Reticulated platelets are the youngest form of circulating platelets characterized by a residual amount of iRNA. It has been suggested that the reticulated platelet count, providing an estimate of thrombopoiesis.
Krsmanović Slavica, Stanković Bratislav   +1 more
doaj  

Impact of high platelet turnover on the platelet transcriptome: Results from platelet RNA-sequencing in patients with sepsis.

PLoS ONE, 2022
BackgroundSepsis is associated with high platelet turnover and elevated levels of immature platelets. Changes in the platelet transcriptome and the specific impact of immature platelets on the platelet transcriptome remain unclear.
Thomas G Nührenberg, Jasmin Stöckle, Federico Marini, Mark Zurek, Björn A Grüning, Vladimir Benes, Lutz Hein, Franz-Josef Neumann, Christian Stratz, Marco Cederqvist, Willibald Hochholzer   +10 more
doaj   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen, Yangyi Wang, Tingting Li, Changqing Guo, Zhe Xie, Zhixian Zhang, Xinghua Han, Wei Wang, Jian Wang, Xiaopeng Ma, Yuanzeng Min   +10 more
wiley   +1 more source

Impact of Reticulated Platelets on the Antiplatelet Effect of the Intravenous P2Y12-Receptor Inhibitor Cangrelor

, 2018
Background Reticulated platelets are associated with impaired antiplatelet response to irreversibly acting P2Y12-receptor inhibitors. However, the impact of reticluated platelets (RP) on the reversibly acting injectable P2Y12-receptor ...
Christian Valina, Nikolaus Löffelhardt, Valina, Christian Marc, Kambis Mashayekhi, Mashayekhi, Kambis, Hochholzer, Willibald, Willibald Hochholzer, Christian Stratz, Neumann, Franz-Josef, Nührenberg, Thomas G., Dietmar Trenk, Thomas Nührenberg, Miroslaw Ferenc, Franz-Josef Neumann, Löffelhardt, Nikolaus, Ferenc, Miroslaw, Trenk, Dietmar, Stratz, Christian   +17 more
core   +1 more source

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

Advanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen, Liangxia Jiang, Xianbin Wang, Lili Zhong, Rongcan Luo, Min Su, Liangzhao Chu, Peng Luo   +7 more
wiley   +1 more source

Reticulated platelet values in normal and thrombocytopenic neonates

The Journal of Pediatrics, 1996
Reticulated platelets (RPs) are newly synthesized platelets with increased ribonucleic acid content. The percentage of RPs is elevated in adults with thrombocytopenia as a result of increased platelet destruction. The objectives of this study were to determine normal RP values in neonates at birth and to determine whether neonates with thrombocytopenia
S M, Peterec, S A, Brennan, H M, Rinder, J L, Wnek, D S, Beardsley   +4 more
openaire   +2 more sources

A Metal‐Polyphenol Self‐Assembled Coated 3D Sponge With Mild Photothermal Antibacterial, Exudate‐Controlling, and Immunomodulatory Functions for Hemostasis and Chronic Wound Healing

Advanced Science, EarlyView.
A thrombin‐functionalized copper‐polydopamine nanofiber sponge integrates rapid hemostasis, mild photothermal antibacterial therapy, stimulus‐responsive Cu2+ release, chemodynamic oxidative stress, and macrophage immunomodulation. This multifunctional dressing suppresses infection, regulates inflammation, promotes angiogenesis and re‐epithelialization,
Ziwei Zhang, Feng Qin, Xiaomeng Zhang, Xueqin Shuang, Jiahua Zhou, Ming Cheng, Baicheng Lu, Mingyue Song, Yuntian Bai, Dianying Zhang, Ming Li, Yanhua Wang   +11 more
wiley   +1 more source

Impact of immature platelet fraction on platelet reactivity during prasugrel maintenance treatment

Platelets, 2019
Residual high on-treatment platelet reactivity (HTPR) despite dual antiplatelet therapy (DAPT) has emerged as a predictor of major ischemic events in patients undergoing percutaneous coronary interventions (PCIs), especially after an acute cardiovascular
Monica Verdoia, Patrizia Pergolini, Roberta Rolla, Harry Suryapranata, Elvin Kedhi, Giuseppe De Luca   +5 more
doaj   +1 more source