Results 141 to 150 of about 42,523 (238)

The diagnostic performance of the basic versus the detailed telomere Flow FISH test in young patients with aplastic anaemia

open access: yesBritish Journal of Haematology, Volume 208, Issue 3, Page 1093-1104, March 2026.
Summary Identifying telomere biology disorders (TBDs) in patients with aplastic anaemia (AA) is essential for guiding appropriate care. Telomere length (TL) measurement by flow cytometry with fluorescence in situ hybridization supports diagnosis, but the real‐world performance of the basic test (lymphocytes and granulocytes) versus the detailed test ...
Nicholas F. DeCleene   +5 more
wiley   +1 more source

Phase II study of the triple combination of rabbit ATG, ciclosporin and eltrombopag in patients with transfusion‐dependent aplastic anaemia: West Japan Hematology Study Group (W‐JHS) AA02 trial

open access: yesBritish Journal of Haematology, Volume 208, Issue 3, Page 1084-1092, March 2026.
Summary The efficacy of a triple combination of rabbit anti‐human thymocyte immunoglobulin (rATG), ciclosporin and eltrombopag (EPAG) was prospectively evaluated in patients with severe or transfusion‐dependent non‐severe aplastic anaemia (SAA) across 29 institutions in Japan. Sixty patients were enrolled, of whom 48 had SAA. The primary end‐point, the
Fumi Nakamura   +17 more
wiley   +1 more source

Single-cell transcriptomics reveals heterocellular γ-globin gene expression in Aγδβ-thalassemia. [PDF]

open access: yesBlood Adv
Doerfler PA   +13 more
europepmc   +1 more source

Age‐Dependent Increase in Small Intestinal Permeability and Sex‐Dependent Absorptive Capacity in Cats (Felis catus)

open access: yesJournal of Animal Physiology and Animal Nutrition, Volume 110, Issue 2, Page 169-176, March 2026.
ABSTRACT Age‐associated changes in intestinal permeability and function have not been studied in domestic cats, leaving a key factor in the relationship between age and digestive health in cats unexplored. Due to factors not currently understood, mature and senior cats may experience a loss of fat and protein digestibility, along with a loss of body ...
Keely Patterson   +6 more
wiley   +1 more source

Comprehensive Phenotypic and Proteomic Analyses of Human Reticulocyte Maturation. [PDF]

open access: yesBlood Red Cells Iron
Leduc M   +9 more
europepmc   +1 more source

Biochemical Responses to Experimentally Induced Short‐Term Low Energy Availability in Athletes: A Systematic Review

open access: yesScandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 3, March 2026.
ABSTRACT Low energy availability (LEA) occurs when dietary energy intake is insufficient to meet the combined demands of exercise and essential physiological functions. Problematic LEA is recognized as the primary driver of Relative Energy Deficiency in Sport (RED‐S), but the short‐term physiological consequences of LEA remain less clearly defined ...
Isabel Guisado‐Cuadrado   +3 more
wiley   +1 more source

Longitudinal metabolomics study of phosphate‐adenine‐guanosine‐glucose‐saline‐mannitol stored red blood cells

open access: yesTransfusion, Volume 66, Issue 3, Page 455-467, March 2026.
Abstract Background The storage of red blood cells (RBCs) is essential for transfusion but leads to storage lesions that compromise RBC quality and increase the risk of transfusion‐related adverse effects, including allergic transfusion reactions (ATRs). Understanding storage‐induced metabolic change is crucial for enhancing transfusion safety.
Gürkan Bal   +5 more
wiley   +1 more source

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