Results 1 to 10 of about 22,655 (235)

Nucleated red blood cells as a prognostic indicator in dogs with anemia [PDF]

Frontiers in Veterinary Science
BackgroundIn human medicine, nucleated red blood cells (NRBCs) in the peripheral blood have been associated with a poor prognosis and increased mortality in critically ill patients. In critically ill dogs, mortality was also significantly associated with
F. Hollmann, V. Geisen, K. Hartmann, R. Doerfelt   +3 more
doaj   +2 more sources

Reticulocyte Count and Exercise Performance in Elite Athletes: A Retrospective Study [PDF]

Sports
Athletes engaged in dynamic sports experience a shortened red blood cell (RBC) lifespan and accelerated turnover due to RBC destruction. This accelerated RBC turnover might have a positive impact on exercise performance by increasing the number of young ...
Kohei Ashikaga, Marco Alfonso Perrone, Antonio Gianfelici, Davide Ortolina, Simone Crotta, Alessandro Spinelli, Sara Monosilio, Giuseppe Di Gioia, Viviana Maestrini, Maria Rosaria Squeo, Antonio Pelliccia   +10 more
doaj   +2 more sources

Choice of lipid supplementation for in vitro erythroid cell culture impacts reticulocyte yield and characteristics [PDF]

Scientific Reports
Lipids, particularly cholesterol, are critical components of red blood cell (RBC) membranes, influencing protein function, cell stability, and deformability. Reticulocytes (young RBC) derived from in vitro erythroid cultures have been reported to possess
C. M. Freire, N. R. King, M. Dzieciatkowska, D. Stephenson, J. G. G. Dobbe, G. J. Streekstra, A. D’Alessandro, T. J. Satchwell, A. M. Toye   +8 more
doaj   +2 more sources

Targeting anemia-induced CD71+ reticulocytes protects mice from Plasmodium infection [PDF]

Infection and Immunity
Malaria, caused by Plasmodium spp., is a global health concern linked to anemia and increased mortality. Compensatory erythropoiesis seen during acute anemia results in an increased circulating reticulocyte count (i.e., immature RBC), a key factor in ...
Sareh Zeydabadinejad, Jong Sung Anthony Kim, Anna Zheng, Mrunmayee Rajendra Kandalgaonkar, Prince Boakye Ababio, Amira Gohara, Matam Vijay-Kumar, Beng San Yeoh, Piu Saha   +8 more
doaj   +2 more sources

Host Reticulocytes Provide Metabolic Reservoirs That Can Be Exploited by Malaria Parasites

PLoS Pathogens, 2015
Human malaria parasites proliferate in different erythroid cell types during infection. Whilst Plasmodium vivax exhibits a strong preference for immature reticulocytes, the more pathogenic P. falciparum primarily infects mature erythrocytes.
Anubhav Srivastava, Darren J Creek, David P De Souza   +2 more
exaly   +2 more sources

The protective effect of the spleen in sickle cell patients. A comparative study between patients with asplenia/hyposplenism and hypersplenism

Frontiers in Physiology, 2022
Sickle cell disease (SCD) is caused by a point mutation in the beta-globin gene. SCD is characterized by chronic hemolytic anemia, vaso-occlusive events leading to tissue ischemia, and progressive organ failure.
Sari Peretz, Sari Peretz, Leonid Livshits, Leonid Livshits, Etheresia Pretorius, Asya Makhro, Anna Bogdanova, Anna Bogdanova, Max Gassmann, Ariel Koren, Carina Levin, Carina Levin   +11 more
doaj   +1 more source

A Proposed Concept for Defective Mitophagy Leading to Late Stage Ineffective Erythropoiesis in Pyruvate Kinase Deficiency

Frontiers in Physiology, 2021
Pyruvate kinase deficiency (PKD) is a rare congenital hemolytic anemia caused by mutations in the PKLR gene. Here, we review pathophysiological aspects of PKD, focusing on the interplay between pyruvate kinase (PK)-activity and reticulocyte maturation in
Annelies Johanna van Vuren, Eduard Johannes van Beers, Richard van Wijk   +2 more
doaj   +1 more source

Reticulocyte Maturation

Membranes, 2022
Changes to the membrane proteins and rearrangement of the cytoskeleton must occur for a reticulocyte to mature into a red blood cell (RBC). Different mechanisms of reticulocyte maturation have been proposed to reduce the size and volume of the reticulocyte plasma membrane and to eliminate residual organelles.
Stevens-Hernandez, Christian J., Bruce, Lesley J   +1 more
openaire   +5 more sources

Clinical utility of immature reticulocyte fraction for identifying early red blood cell regeneration in anemic dogs

Journal of Veterinary Internal Medicine, 2023
Background Evaluating regeneration is essential for the classification and differential diagnosis of anemia in dogs. Early detection of regeneration is challenging in anemic dogs. Objectives This study assessed the value of immature reticulocyte fraction
Jae‐Ha Jung, Yeseul Yang, Dansong Seo, Soyeon Cho, Goeun Choi, Yongbaek Kim   +5 more
doaj   +1 more source

A brief overview of BNIP3L/NIX receptor‐mediated mitophagy

FEBS Open Bio, 2021
Mitophagy is a form of autophagy specialized to selectively remove mitochondria. Although the PINK1/Parkin pathway is the best described mitophagy of damaged mitochondria, receptor/mediated mitophagy seems to have a pivotal role in cellular development ...
Mija Marinković, Ivana Novak
doaj   +1 more source