Results 21 to 30 of about 321,318 (176)

U-Net with Hierarchical Bottleneck Attention for Landmark Detection in Fundus Images of the Degenerated Retina [PDF]

open access: yesOphthalmic Medical Image Analysis 2021, 2021
Fundus photography has routinely been used to document the presence and severity of retinal degenerative diseases such as age-related macular degeneration (AMD), glaucoma, and diabetic retinopathy (DR) in clinical practice, for which the fovea and optic disc (OD) are important retinal landmarks.
arxiv   +1 more source

First reported case of Doyne honeycomb retinal dystrophy (Malattia Leventinese/autosomal dominant drusen) in Scandinavia

open access: yesMolecular Genetics & Genomic Medicine, 2021
Doyne honeycomb retinal dystrophy (DHRD)/malattia leventinese (ML) is an autosomal dominant, progressive retinal disorder characterized by massive central retinal drusen often partly coalescent forming a characteristic honeycomb‐like pattern.
I. Sheyanth   +5 more
semanticscholar   +1 more source

Anomalous angiogenesis in retina [PDF]

open access: yesBiomedicines 9, 224 (2021), 2021
Age-related macular degeneration (AMD) may cause severe loss of vision or blindness particularly in elderly people. Exudative AMD is characterized by angiogenesis of blood vessels growing from underneath the macula, crossing the blood-retina barrier (that comprise Bruch's membrane, BM, and the retinal pigmentation epithelium RPE), leaking blood and ...
arxiv   +1 more source

Unstimulated, Serum-free Cultures of Retinal Pigment Epithelium Excrete Large Mounds of Drusen-like Deposits

open access: yesCurrent Eye Research, 2020
Purpose: A hallmark of age-related macular degeneration is the accumulation of deposits of lipids and proteins, called drusen, in Bruch’s membrane. Several culture models of retinal pigment epithelia (RPE) develop drusen-like deposits.
Xiaoyu Chen   +3 more
semanticscholar   +1 more source

ROCT-Net: A new ensemble deep convolutional model with improved spatial resolution learning for detecting common diseases from retinal OCT images [PDF]

open access: yes, 2022
Optical coherence tomography (OCT) imaging is a well-known technology for visualizing retinal layers and helps ophthalmologists to detect possible diseases. Accurate and early diagnosis of common retinal diseases can prevent the patients from suffering critical damages to their vision.
arxiv   +1 more source

Unilateral buried optic nerve head drusen triggering central retinal vein occlusion in young – Discovering an eclipsed entity

open access: yesOman Journal of Ophthalmology, 2023
Optic nerve head (ONH) drusen are acellular calcified concretions. Buried drusen manifests as pseudopapilledema. The compressive effects of ONH drusen can rarely precipitate central retinal vein occlusion (CRVO).
Muthu Krishnan Vallinayagam   +3 more
doaj   +1 more source

Retinal Angiomatous Proliferation in an Eye with Cuticular Drusen

open access: yesCase Reports in Ophthalmology, 2015
Purpose: To report the presence of retinal angiomatous proliferation (RAP) in an eye with cuticular drusen detected by fluorescein and indocyanine green angiography by confocal scanning laser ophthalmoscopy and by spectral-domain optical coherence ...
Atsuko Sato   +3 more
doaj   +1 more source

Abundant lipid and protein components of drusen. [PDF]

open access: yesPLoS ONE, 2010
Drusen are extracellular lesions characteristic of aging and age-related maculopathy, a major retinal disease of the elderly. We determined the relative proportions of lipids and proteins in drusen capped with retinal pigment epithelium (RPE) and in RPE ...
Lan Wang   +6 more
doaj   +1 more source

A deep learning framework for the detection and quantification of drusen and reticular pseudodrusen on optical coherence tomography [PDF]

open access: yes, 2022
Purpose - To develop and validate a deep learning (DL) framework for the detection and quantification of drusen and reticular pseudodrusen (RPD) on optical coherence tomography scans. Design - Development and validation of deep learning models for classification and feature segmentation.
arxiv   +1 more source

Developing an image-based grading scale for peripheral drusen to investigate associations of peripheral drusen type with age-related macular degeneration

open access: yesScientific Reports
Age-related macular degeneration (AMD) is a leading cause of blindness. It is associated with peripheral drusen which has not been categorized. We investigated peripheral drusen to validate an image grading system and to understand possible associations ...
Paripoorna Sharma   +4 more
doaj   +1 more source

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