Results 51 to 60 of about 11,522 (195)

Low-Reflectivity Drusen With Overlying RPE Damage Revealed by Spectral-Domain OCT: Hint for the Development of Age-Related Macular Degeneration

Frontiers in Medicine, 2021
Purpose: To observe the relationship between the characteristic changes in the drusen morphology revealed by the spectral-domain optical coherence tomography (SD-OCT) and the progression of age-related macular degeneration (AMD).Methods: A total of 380 ...
Shasha Yang, Zongyin Gao, Haijiang Qiu, Chengguo Zuo, Lan Mi, Hui Xiao, Xing Liu   +6 more
doaj   +1 more source

Transmission Electron Microscopy Data on drusen-like deposits in the retinal degeneration sTg-IRBP: HEL mouse model

Data in Brief, 2019
Histology (H&E) and transmission electron microscopy (TEM) data are provided showing age-related changes in the retinal structure of sTg-IRBP:HEL mice.
Yi-Hsia Liu, Christine Mölzer, Gillian C. Milne, Lucia Kuffová, John V. Forrester   +4 more
doaj   +1 more source

Analysis of Macular Drusen and Blood Test Results in 945 Macaca fascicularis. [PDF]

PLoS ONE, 2016
Age-dependent formation of macular drusen caused by the focal accumulation of extracellular deposits beneath the retinal pigment epithelium precede the development of age-related macular degeneration (AMD), one of the leading causes of blindness ...
Koji M Nishiguchi, Yu Yokoyama, Yusuke Fujii, Kosuke Fujita, Yusuke Tomiyama, Ryo Kawasaki, Toshinori Furukawa, Fumiko Ono, Nobuhiro Shimozawa, Mutsumi Togo, Michihiro Suzuki, Toru Nakazawa   +11 more
doaj   +1 more source

Unilateral Acute Anterior Ischemic Optic Neuropathy in a Patient with an Already Established Diagnosis of Bilateral Optic Disc Drusen

Case Reports in Ophthalmological Medicine, 2015
Optic disc drusen (ODD) are calcific deposits that form in the optic nerve head secondary to abnormalities in axonal metabolism and degeneration. Anterior ischemic optic neuropathy, central retinal artery, and vein occlusion are among the rare vascular ...
Ziya Ayhan, Aylin Yaman, Meltem Söylev Bajin, A. Osman Saatci   +3 more
doaj   +1 more source

Amyloid β peptides overexpression in retinal pigment epithelial cells via AAV-mediated gene transfer mimics AMD-like pathology in mice

Scientific Reports, 2017
Age-related macular degeneration (AMD) is a progressive retinal neurodegenerative disorder characterized by extracellular deposits known as drusen. A major constituent of drusen deposits are Alzheimer disease-associated amyloid β (Aβ) peptides.
Tuhina Prasad, Ping Zhu, Amrisha Verma, Paramita Chakrabarty, Awilda M. Rosario, Todd E. Golde, Qiuhong Li   +6 more
doaj   +1 more source

Prevalence of retinal pathologies in people over 60 years: the Tehran Geriatrics Eye Study [PDF]

International Journal of Ophthalmology
AIM: To determine the prevalence of some retinal pathologies in people over 60y and their association with demographic and ocular factors. METHODS: A cross-sectional study was conducted in Tehran using multistage cluster sampling.
Abolghasem Mortazavi, Alireza Hashemi, Alirerza Jamali, Hassan Hashemi, Mohammadreza Aghamirsalim, Mehdi Khabazkhoob   +5 more
doaj   +1 more source

Diagnostics of optic disk drusen in children

Oftalʹmologiâ, 2016
Diagnosis of deep optic disc drusen (OND) in children is difficult because they are not visualized ophthalmoscopically and often mimic a picture of stagnation, identifying the wrong tactics diagnostic and therapeutic actions.Materials and Methods ...
A. G. Shchuko, D. U. Samsonov, S. I. Zhukova, T. N. Iureva   +3 more
doaj   +1 more source

Apolipoprotein Localization in Isolated Drusen and Retinal Apolipoprotein Gene Expression

Investigative Opthalmology & Visual Science, 2006
To evaluate apolipoprotein (Apo) gene expression in native human retinal pigment epithelium (RPE) and neurosensory retina and to detect apolipoproteins within age-related, extramacular drusen.Drusen were isolated manually from 10 eyes of 10 donors (age range, 58-93 years) with grossly normal maculas that were preserved in 4% paraformaldehyde within 6 ...
Chuan-Ming, Li, Mark E, Clark, Melissa F, Chimento, Christine A, Curcio   +3 more
openaire   +2 more sources

Changes of drusen number and central retinal thickness in age-related macular degeneration patients over two years

Acta Clinica Croatica, 2016
Age-related macular degeneration (ARMD) is the leading cause of blindness in developed world but there are still much unknown facts about the disease itself.
Krešimir Mandić, Nenad Vukojević, Tomislav Jukić, Damir Katušić, Jelena Juri Mandić   +4 more
doaj   +1 more source

Automated detection of retinal exudates and drusen in ultra-widefield fundus images based on deep learning [PDF]

, 2021
Zhongwen Li, Chong Guo, Danyao Nie, Duoru Lin, Tingxin Cui, Yi Zhu, Chuan Chen, Lanqin Zhao, Xulin Zhang, Meimei Dongye, Dongni Wang, Fabao Xu, Chenjin Jin, Ping Zhang, Yu Han, Pisong Yan, Haotian Lin   +16 more
openalex   +1 more source