Results 51 to 60 of about 321,318 (176)

Drusen diagnosis comparison between hyper-spectral and color retinal images.

Biomedical Optics Express, 2019
Age-related macular degeneration (AMD) is a degenerative aging disorder, which can lead to irreversible vision loss in older individuals. The emergence of clinical applications of retinal hyper-spectral imaging provides a unique opportunity to capture ...
Yiyang Wang, Brian T. Soetikno, J. Furst, D. Raicu, A. Fawzi   +4 more
semanticscholar   +1 more source

Age‐Associated Decline in Autophagy Pathways in the Retinal Pigment Epithelium and Protective Effects of Topical Trehalose in Light‐Induced Outer Retinal Degeneration in Mice

Aging Cell, EarlyView.
Transcriptomic analyses reveal an age‐related decline in autophagy pathways in RPE/choroid. These pathways remain unchanged in early AMD but become bidirectionally dysregulated in later stages, along with increased RPE loss. Pre‐treatment with trehalose eyedrops enhances RPE autophagy flux and prevents light‐induced outer retinal degeneration in mice ...
Katherine Cox, Gongyu Shi, Neve Read, Mohamed T. Patel, Kepeng Ou, Zijia Liu, Jiahui Wu, Suci Cendanawati, Jenna Le Brun Powell, Pola Goldberg Oppenheimer, Lisa J. Hill, Lindsay B. Nicholson, Andrew D. Dick, Jian Liu   +13 more
wiley   +1 more source

An Explainable Fully Dense Fusion Neural Network with Deep Support Vector Machine for Retinal Disease Determination

International Journal of Computational Intelligence Systems, 2023
Retinal issues are crucial because they result in visual loss. Early diagnosis can aid physicians in initiating treatment and preventing visual loss.
Ismail Kayadibi, Gür Emre Güraksın
semanticscholar   +1 more source

Retinal phenotyping of variants of Alzheimer's disease using ultra‐widefield retinal images

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021
Background Posterior cortical atrophy (PCA) is the most common atypical variant of Alzheimer's disease (AD). Changes associated with PCA in the brain affect the visual cortex, but little is known about retinal changes in PCA.
Lajos Csincsik, Nicola Quinn, Keir X. X. Yong, Sebastian J. Crutch, Tunde Peto, Imre Lengyel   +5 more
doaj   +1 more source

Low-Reflectivity Drusen With Overlying RPE Damage Revealed by Spectral-Domain OCT: Hint for the Development of Age-Related Macular Degeneration

Frontiers in Medicine, 2021
Purpose: To observe the relationship between the characteristic changes in the drusen morphology revealed by the spectral-domain optical coherence tomography (SD-OCT) and the progression of age-related macular degeneration (AMD).Methods: A total of 380 ...
Shasha Yang, Zongyin Gao, Haijiang Qiu, Chengguo Zuo, Lan Mi, Hui Xiao, Xing Liu   +6 more
doaj   +1 more source

Normative prospective data on automatically quantified retinal morphology correlated to retinal function in healthy ageing eyes by two microperimetry devices

Acta Ophthalmologica, EarlyView.
Abstract Purpose The relationship between retinal morphology, as assessed by optical coherence tomography (OCT), and retinal function in microperimetry (MP) has not been well studied, despite its increasing importance as an essential functional endpoint for clinical trials and emerging therapies in retinal diseases.
Klaudia Birner, Leonard M. Coulibaly, Johannes Schrittwieser, Irene Steiner, Hamza Mohamed, Simon Schürer‐Waldheim, Markus Gumpinger, Hrvoje Bogunovic, Ursula Schmidt‐Erfurth, Gregor S. Reiter   +9 more
wiley   +1 more source

Impact of drusen and drusenoid retinal pigment epithelium elevation size and structure on the integrity of the retinal pigment epithelium layer

British Journal of Ophthalmology, 2018
Purpose To evaluate the impact of drusen size and structure on retinal pigment epithelium (RPE) and photoreceptor layers in eyes with early to intermediate age-related macular degeneration (AMD) using polarisation-sensitive optical coherence tomography ...
F. Schlanitz, B. Baumann, S. Sacu, L. Baumann, M. Pircher, C. Hitzenberger, U. Schmidt-Erfurth   +6 more
semanticscholar   +1 more source

Laser photocoagulation of soft macular drusen

Офтальмохирургия, 2013
Purpose. The assessment of morphological and functional results of the threshold photocoagulation in eyes with large soft macular drusen. Material and methods. Thirty four patients (39 eyes) were enrolled in the study.
L.I. Balashevich, M.V. Gatsu, M.V. Gordeyeva   +2 more
doaj  

Posterior segment abnormalities in posterior microphthalmos

American Journal of Ophthalmology Case Reports, 2020
Purpose: We report a case of posterior microphthalmos with characteristic papillomacular retinal folds, pigmentary retinopathy, and optic disc drusen.
Nilesh Raval, Cheng Zhang, Wen-Jeng Yao, James Lin   +3 more
doaj  

Semaglutide and non‐arteritic anterior ischaemic optic neuropathy: Review and interpretation of reported association

Acta Ophthalmologica, EarlyView.
Abstract This review covers a seminal study of the relation between exposure to the glucagon‐like peptide 1 (GLP‐1) agonist semaglutide and incident non‐arteritic anterior ischaemic optic neuropathy (NAION) in a neuro‐ophthalmology clinic setting, subsequent studies in unselected populations, a meta‐analysis of clinical trials and pathophysiology ...
Abdullah Amini, Steffen Hamann, Michael Larsen   +2 more
wiley   +1 more source