Results 61 to 70 of about 11,541 (214)

Population-Based Prevalence and 5-Year Change of Soft Drusen, Pseudodrusen, and Pachydrusen in a Japanese Population

open access: yesOphthalmology Science, 2021
Purpose: To elucidate the prevalence of soft drusen, pseudodrusen, and pachydrusen and their 5-year changes in a Japanese population. Design: Longitudinal population-based cohort study conducted from 2013 through 2017. Participants: Residents 40 years of
Miki Sato-Akushichi, MD   +7 more
doaj   +1 more source

Visual Function Assessment in Geographic Atrophy: A Review

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Geographic atrophy (GA) causes significant vision impairment and reduction in vision‐related quality of life. Fundus autofluorescence (FAF) is the gold standard of structural assessment of GA but is a surrogate marker for vision loss, which can be assessed by tests of visual function and functional vision.
Ye Li, Lauren N. Ayton, Adrian T. Fung
wiley   +1 more source

Intraocular Osseous Metaplasia in Norfolk Black Turkey (Meleagris gallopavo): Clinicopathological Characterization of a Rare Avian Condition

open access: yesVeterinary Ophthalmology, EarlyView.
ABSTRACT Background Osseous metaplasia is a rare condition characterized by abnormal bone growth in soft tissues. Although documented in mammals, intraocular osseous metaplasia is uncommon in avian species and has been poorly characterized in turkeys (Meleagris gallopavo).
Taina dos Santos Alberti   +6 more
wiley   +1 more source

Optic disc drusen precipitating central retinal vein occlusion in young [PDF]

open access: yesBMJ Case Reports, 2019
A 17-year-old boy presented with sudden painless diminution of vision in right eye for 3 days. The best corrected visual acuity was 20/400 and 20/20 in right and left eye, respectively. The intraocular pressures were 12 mm Hg in both eyes.
Srikanta Kumar Padhy   +1 more
openaire   +2 more sources

Retinal phenotyping of variants of Alzheimer's disease using ultra‐widefield retinal images

open access: yesAlzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021
Background Posterior cortical atrophy (PCA) is the most common atypical variant of Alzheimer's disease (AD). Changes associated with PCA in the brain affect the visual cortex, but little is known about retinal changes in PCA.
Lajos Csincsik   +5 more
doaj   +1 more source

Therapeutic Potential of Resveratrol in Cancer and Neurodegenerative Disorders: A Current Review

open access: yesBioFactors, Volume 52, Issue 1, January/February 2026.
Resveratrol induces the expressions of TP53, NRF2, and JDP2 axis in cancer cells to control ROS balance in mitochondria. The antioxidation responses were induced through SRIT1/3, HDAC, STAT3, TGFβ, and so on, to trigger the inflammation, and NFkB response to lead to the cell death of cancers or neuro‐damaged cells.
Kenly Wuputra   +9 more
wiley   +1 more source

Automated drusen detection in retinal images using analytical modelling algorithms [PDF]

open access: yesBioMedical Engineering OnLine, 2011
Drusen are common features in the ageing macula associated with exudative Age-Related Macular Degeneration (ARMD). They are visible in retinal images and their quantitative analysis is important in the follow up of the ARMD. However, their evaluation is fastidious and difficult to reproduce when performed manually.This article proposes a methodology ...
Manivannan Ayyakkannu   +3 more
openaire   +3 more sources

LASER PHOTOCOAGULATION OF SOFT MACULAR DRUSEN

open access: yesОфтальмохирургия, 2015
Purpose. The assessment of morphological and functional results of the threshold photocoagulation in eyes with large soft macular drusen. Material and methods. Thirty four patients (39 eyes) were enrolled in the study.
L. I. Balashevich   +2 more
doaj  

A semi-automated pipeline for quantifying drusen-like deposits in human induced pluripotent stem cell-derived retinal pigment epithelium cells

open access: yesSLAS Technology
Age-Related Macular Degeneration (AMD) is a highly prevalent form of retinal disease amongst Western communities over 50 years of age. A hallmark of AMD pathogenesis is the accumulation of drusen underneath the retinal pigment epithelium (RPE), a ...
Jenna Hall   +14 more
doaj   +1 more source

Low-Reflectivity Drusen With Overlying RPE Damage Revealed by Spectral-Domain OCT: Hint for the Development of Age-Related Macular Degeneration

open access: yesFrontiers in Medicine, 2021
Purpose: To observe the relationship between the characteristic changes in the drusen morphology revealed by the spectral-domain optical coherence tomography (SD-OCT) and the progression of age-related macular degeneration (AMD).Methods: A total of 380 ...
Shasha Yang   +6 more
doaj   +1 more source

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