FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu +5 more
wiley +1 more source
Unraveling the immune response in optic nerve injury: implications for retinal ganglion cell protection. [PDF]
Xu K +5 more
europepmc +1 more source
Extracellular Vesicles: Biology, Intercellular Communication and Therapeutic Potential in Diabetes
Exosome packaging in diabetes mellitus is depicted. Induced expression levels of RBP4, WNT related proteins, TGFB1, BMPs, VEGFs, STAT3, Calpain2 and altered expression levels of microRNAs in the exosomes are responsible for the inflammatory actions, defective central metabolism, myofibroblasts proliferation, dysregulated cell migration, cell ...
Swayam Prakash Srivastava +9 more
wiley +1 more source
Enhanced Retinal Ganglion Cell Survival via Autophagy Activation in a Novel Retinal Ischemia/Reperfusion Rat Model. [PDF]
Lee SH +4 more
europepmc +1 more source
The Lipoxin LXB4 Reduces Mitochondrial Oxidative Stress in Retinal Ganglion Cells
Izhar Livne‐Bar +3 more
openalex +1 more source
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun +15 more
wiley +1 more source
Spatiotemporal Immune Dynamics in Experimental Retinal Ganglion Cell Injury Models. [PDF]
Yang C +6 more
europepmc +1 more source
Rod inputs to macaque ganglion cells and their temporal dynamics [PDF]
Kremers, J. +3 more
core +1 more source
Impact of retinal ganglion cell loss on human pattern recognition
MiYoung Kwon
openalex +1 more source
Real-Time Dynamics of Ca2+, Phosphatidylserine, Caspase-3/7, and Morphological Changes in Apoptosis: Retinal Ganglion Cells Under Elevated Pressure [PDF]
Siyuan Lu, Jae Kyoo Lee, A. Madhukar
openalex +1 more source

