Results 211 to 220 of about 72,734 (313)

Retinal ganglion cell degeneration in glaucoma disrupts HPA axis temporal organization and dampens corticosterone production. [PDF]

J Neuroendocrinol
Barsanele PS, da Silva JJ, Cortes BFDS, de Oliveira Furtado EM, Cipolla-Neto J, de Assis LVM, Poletini MO, Moraes MN.   +7 more
europepmc   +1 more source

Disrupted Vestibular Nuclei Neuron Development in a Chick Model for Congenital Vestibular Disorders

Developmental Neurobiology, Volume 86, Issue 3, July 2026.
ABSTRACT Children with syndromic, congenital vestibular disorders (CVDs) form a sac‐like inner ear with missing or truncated semicircular canals and experience delayed motor development with lifelong challenges to maintain posture and balance. How the abnormal inner ear affects downstream central vestibular neural circuitry has not been investigated ...
Elizabeth B. Bogin, Rossella Conti, Kathleen Gallagher, Kaya Oguz, Anastas Popratiloff, Kenna D. Peusner   +5 more
wiley   +1 more source

Microglial Pruning of Excitatory Synapses in the Hippocampus Is Complement C3‐Independent in Physiological and Neuroinflammatory States

Glia, Volume 74, Issue 7, July 2026.
In development, microglia engulfment of hippocampal excitatory synapses is unperturbed in C3‐lacking mice. Peripheral inflammation induces a neuroinflammatory phenotype and synapse loss in the hippocampus independent of complement cascade activation. ABSTRACT A key feature of brain development is the refinement of exuberant synapses, known as synapse ...
Eric W. Salter, Ashish Kadia, Lijia Zhang, Jonathan S. Thacker, Sun‐Lim Choi, Liam T. Ralph, Gang Lei, Fuzi Jin, John Georgiou, Graham L. Collingridge   +9 more
wiley   +1 more source

Editorial: Dynamics of endocrine system dysfunctions and neuro-ophthalmic manifestations: early diagnostic to therapeutic implications

Frontiers in Endocrinology
Dhiraj Kumar, Ahmad Abu Turab Naqvi, Rohan Gupta, Smita Kumari, Rashid Waseem, Md. Imtaiyaz Hassan   +5 more
doaj   +1 more source

The mitochondria-targeted peptide HDAP2 reduces mitochondrial loss and retinal ganglion cell degeneration after optic nerve injury. [PDF]

Neuroscience
MacNeil MA, Arain S, Mentor W, Garcia-Marin V, Birk A.   +4 more
europepmc   +1 more source

Astrocyte Mechanobiology: Linking Biomechanical Forces to Biochemical Signaling in the Central Nervous System

Glia, Volume 74, Issue 7, July 2026.
Astrocytes are key sensors and transducers of biomechanical stimuli within the central nervous system. Astrocyte development is highly dependent on mechanical stimuli such as surrounding tissue stiffness and biomechanical strain. Mechanosensory pathways including integrins, connexins and pannexins, and mechanosensitive channels regulate astrocyte ...
Ana N. Strat, Alima Ahmed, Mariano Viapiano, Preethi S. Ganapathy   +3 more
wiley   +1 more source

Anti-Apoptotic and Neurite-Protective Nanomedicine Augments Embryonic Stem Cells-Derived Retinal Ganglion Cell Transplantation in Glaucoma Recovery. [PDF]

Adv Sci (Weinh)
Chen M, Jiang X, Wang Y, Luo Z, Zhang Y, Liu S, Huang R, Zhang D, Tang Z, Ju Y, Pan S, Ni N, Feng W, Chen Y, Gu P.   +14 more
europepmc   +1 more source

First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT This guideline summarizes diagnostic and therapeutic approaches based on a systematic literature review and evidence evaluation using the GRADE methodology. Given the limited high‐quality data, expert consensus was additionally obtained through a modified Delphi process.
Giorgia Olivieri, Andrea Bordugo, Birute Burnyte, Alessandro Costetti, Maria‐Luz Couce, Luisa Diogo, Francois Feillet, D. Sean Froese, Benedetta Greco, Jean‐Louis Gueant, Luciana Hannibal, Friederike Hörster, Viktor Kožich, Giancarlo La Marca, Irini Manoli, Fanny Mochel, Lorenzo Orazi, Belén Pérez, Manuel Schiff, Bernd C. Schwahn, Ida Schwartz, Karolina M. Stepien, Jolanta Sykut‐Cegielska, Trine Tangeraas, Rolf H. Zetterström, Carlo Dionisi‐Vici, Martina Huemer   +26 more
wiley   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva, Yann Nadjar, Manuel Schiff, Christine Vianey‐Saban, Alain Fouilhoux, Jean‐François Benoist   +5 more
wiley   +1 more source

Unraveling the immune response in optic nerve injury: implications for retinal ganglion cell protection. [PDF]

Front Immunol
Xu K, Yu L, Zhang N, Dong M, Xing Y, Yang N.   +5 more
europepmc   +1 more source