Results 221 to 230 of about 5,405,992 (262)
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Intrinsically Photosensitive Retinal Ganglion Cells
Journal of Neuro-Ophthalmology, 2007The recent discovery of melanopsin-expressing retinal ganglion cells that mediate the pupil light reflex has provided new insights into how the pupil responds to different properties of light. These ganglion cells are unique in their ability to transduce light into electrical energy.
Aki, Kawasaki, Randy H, Kardon
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Activation of autophagy in retinal ganglion cells
Journal of Neuroscience Research, 2008AbstractAutophagy has been shown to be activated in neuronal cells in response to injury and suggested to have a cell‐protective role in neurodegenerative diseases. In this study, we investigated the activation of autophagy in retinal ganglion cells (RGCs) following optic nerve transection (ONT) and evaluated its effect on RGC survival.
Seok Hwan, Kim +7 more
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The autoregulation of retinal ganglion cell number
Development, 2001ABSTRACT The development of the nervous system is dependent on a complex set of signals whose precise co-ordination ensures that the correct number of neurones are generated. This regulation is achieved through a variety of cues that influence both the generation and the maintenance of neurones during development.
González-Hoyuela, M. +2 more
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Culture of rat retinal ganglion cells
Journal of Huazhong University of Science and Technology [Medical Sciences], 2011This study aimed to modify the mixed and purified culture of rat retinal ganglion cells (RGCs) in vitro. The retinae of 1-3 day old Sprague-Dawley (SD) rats were separated bluntly into two layers: inner layer and outer layer, under a surgical microscope. Retinal cells isolated from different layers (inner layer, outer layer and whole retinal tissue) by
Zhirong, Xu +4 more
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Topography of pig retinal ganglion cells
Journal of Comparative Neurology, 2005AbstractIn the present work we analyzed the distribution of retinal ganglion cells (RGCs) in the pig retina. RGCs were retrogradely labeled in vivo by injecting Fluoro‐Gold into the optic nerve. RGC density and the distribution of RGCs in terms of soma size were analyzed. Different regions of the porcine retina were identified following analysis of the
Mónica, Garcá +3 more
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Feature Detection by Retinal Ganglion Cells
Annual Review of Vision Science, 2022Retinal circuits transform the pixel representation of photoreceptors into the feature representations of ganglion cells, whose axons transmit these representations to the brain. Functional, morphological, and transcriptomic surveys have identified more than 40 retinal ganglion cell (RGC) types in mice.
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Peptides influence retinal ganglion cells
Neuroscience Letters, 1981Neurotensin, substance P and (D-Ala2, Met5)-enkephalinamide were iontophoresed onto ganglion cells of the amphibian retina. Substance P and neurotensin were found to be excitatory while (D-Ala2, Met5)-enkephalinamide suppressed all types of ganglion cells. These findings are consistent with a functional role for peptides in the vertebrate retina.
E, Dick, R F, Miller
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Towards Retinal Ganglion Cell Regeneration
Regenerative Medicine, 2012Traumatic optic nerve injury and glaucoma are among the leading causes of incurable vision loss across the world. What is worse, neither pharmacological nor surgical interventions are significantly effective in reversing or halting the progression of vision loss.
Huasong, Gao +7 more
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Retinal Ganglion Cell Axon Fractionation
2023Retinal ganglion cell (RGC) axon regeneration in mammals can be stimulated through gene knockouts, pharmacological agents, and biophysical stimulation. Here we present a fractionation method to isolate regenerating RGC axons for downstream analysis using immunomagnetic separation of cholera toxin subunit B (CTB)-bound RGC axons.
Sean D, Meehan, Sanjoy, Bhattacharya
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1988
Ganglion cells typically make up the innermost layer of the vertebrate retina. They are the only cells with axons that leave the eye. These axons form the optic nerve. Ganglion cell dendrites ramify in the inner nuclear layer, where they are postsynaptic to bipolar cells, which provide a direct input pathway from the outer plexiform layer, and to ...
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Ganglion cells typically make up the innermost layer of the vertebrate retina. They are the only cells with axons that leave the eye. These axons form the optic nerve. Ganglion cell dendrites ramify in the inner nuclear layer, where they are postsynaptic to bipolar cells, which provide a direct input pathway from the outer plexiform layer, and to ...
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