Results 221 to 230 of about 72,734 (313)

A TRIP‐nano killer silencing the pain pacemakers

The Journal of Physiology, EarlyView.
Elisabetta Cerbai
wiley   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Blue Light Induces Retinal Ganglion Cell Damage by Stimulating Drp1-Dependent Mitochondrial Fission and Activating NF-κB/NOX4 Axis. [PDF]

Invest Ophthalmol Vis Sci
Han XH, Wang T, Sun GF, Xie X, Zhang K, Wang XY, Zhang Z, Wang X, Qu XH, Han XJ.   +9 more
europepmc   +1 more source

Agreement between ganglion cell‐inner plexiform layer metrics from widefield optical coherence tomography and Goldmann II, III, and V in glaucoma

Optometry and Vision Science, Volume 103, Issue 7, July 2026.
ABSTRACT Purpose To compare concordance between ganglion cell‐inner plexiform layer metrics acquired using widefield optical coherence tomography (OCT) and visual function assessed using Goldmann (G) II, III, and V stimulus sizes, in turn evaluating the role of spatial summation properties in binary classification of visual field (VF) results.
Janelle Tong, Jack Phu, David Alonso‐Caneiro, Jason Kugelman, Michael Kalloniatis, Ashish Agar, Minas Coroneo, Sieu Khuu   +7 more
wiley   +1 more source

Spatiotemporal Immune Dynamics in Experimental Retinal Ganglion Cell Injury Models. [PDF]

Immun Inflamm Dis
Yang C, Wang X, Ye X, Shen Y, Tong J, Zhang X, Zhou Y.   +6 more
europepmc   +1 more source

Humanin Mitigates Aβ‐Induced Retinal Pigment Epithelium Injury via AMPK‐Beclin1‐Dependent Mitophagy

Aging Cell, Volume 25, Issue 7, July 2026.
Humanin (HN) enhanced the clearance of Aβ‐accumulated mitochondria in the RPE while preserving retinal function and RPE barrier integrity. HN activated AMP‐activated protein kinase (AMPK), leading to phosphorylation of ULK1 and Beclin1, which promoted the interaction between Beclin1 and Parkin and their translocation to mitochondria.
Ha Young Jang, Suyeon Choi, Soo‐Jin Kim, Sooyun Kim, Dong Hyun Jo, Tae Geol Lee, Kyu‐Sang Park, Jeong Hun Kim   +7 more
wiley   +1 more source

The 5-HT1A receptor antagonist WAY-100635 maleate promotes retinal ganglion cell differentiation and protects the retino-visual circuits. [PDF]

Commun Med (Lond)
Dutta S, Surma ML, Chen J, Anbarasu K, Meng J, Wang N, Das A.   +6 more
europepmc   +1 more source

Engineering Extracellular Vesicles for Anti‐Aging Therapy: Mechanisms, Applications, and Perspectives

Aging Cell, Volume 25, Issue 7, July 2026.
This review systematically elucidates the multifactorial anti‐aging mechanisms of extracellular vesicles (EVs). By bridging fundamental biology with advanced bioengineering, scalable manufacturing, and clinical translation, it establishes a comprehensive framework for developing next‐generation EVs‐based precision nanotherapeutics to combat systemic ...
Xian Huang, Qiujie Li, Guofang Tao, Xulin Gan, Jiangjie Lu, Sergei Krasny, Liyun Shi   +6 more
wiley   +1 more source

Pro-inflammatory S100A9 contributes to retinal ganglion cell degeneration in glaucoma. [PDF]

Front Immunol
Wang Z, Chen Y, Wang J, Xiu W, Zhang G, Gao Y, Li A, Long P, Deng B, He C, Lu F.   +10 more
europepmc   +1 more source

The technical and practical implementation of fundus photography in equids

Equine Veterinary Education, Volume 38, Issue 7, Page 371-381, July 2026.
Summary Background Fundus photography is an important diagnostic tool in human and veterinary medicine. Advances in research are increasing its accessibility in human medicine. However, there is a lack of studies on modern fundus photography in animals, particularly in horses. Objectives To assess the use of a portable fundus camera developed for human
I. Vierling, B. Wollanke, V. Franzen
wiley   +1 more source