Results 41 to 50 of about 103,275 (189)
Neuroprotective Effect of Tauroursodeoxycholic Acid on N-Methyl-D-Aspartate-Induced Retinal Ganglion Cell Degeneration. [PDF]
PLoS ONE, 2015 Retinal ganglion cell degeneration underlies the pathophysiology of diseases affecting the retina and optic nerve. Several studies have previously evidenced the anti-apoptotic properties of the bile constituent, tauroursodeoxycholic acid, in diverse ...
Violeta Gómez-Vicente +7 more
doaj +1 more source
Targeting retinal ganglion cell recovery [PDF]
Eye, 2017 Accumulating evidence from experimental and clinical studies suggest that retinal ganglion cells at least in the earlier stages of glaucoma have the capacity to recover function following periods of functional loss. The capacity for recovery may be negatively impacted by advancing age but can be boosted by interventions such as diet restriction and ...
Steven Petrou +6 more
openaire +3 more sources
Neural Regeneration Research, 2016 Bone marrow mesenchymal stem cells can reduce retinal ganglion cell death and effectively prevent vision loss. Previously, we found that during differentiation, female rhesus monkey bone marrow mesenchymal stem cells acquire a higher neurogenic potential
Jing Yuan, Jian-xiong Yu
doaj +1 more source
Transformation of stimulus correlations by the retina [PDF]
, 2013 Redundancies and correlations in the responses of sensory neurons seem to waste neural resources but can carry cues about structured stimuli and may help the brain to correct for response errors. To assess how the retina negotiates this tradeoff, we measured simultaneous responses from populations of ganglion cells presented with natural and artificial
arxiv +1 more source
Single-cell RNA sequencing analysis of the retina under acute high intraocular pressure
Neural Regeneration ResearchHigh intraocular pressure causes retinal ganglion cell injury in primary and secondary glaucoma diseases, yet the molecular landscape characteristics of retinal cells under high intraocular pressure remain unknown. Rat models of acute hypertension ocular
Shaojun Wang +7 more
doaj +1 more source
Biolistic Labeling of Retinal Ganglion Cells
, 2017 Labeling of cellular structures is of fundamental importance in the investigation of diseases of the central nervous system. Biolistic labeling of retinal ganglion cells (RGCs) allows visualization of dendritic and synaptic structures of RGCs in retinal explants from animal models of experimental glaucoma.
Santina, Luca Della, Ou, Yvonne
openaire +6 more sources
Ganglion cell and displaced amacrine cell density distribution in the retina of the howler monkey (Alouatta caraya). [PDF]
PLoS ONE, 2014 Unlike all other New World (platyrrine) monkeys, both male and female howler monkeys (Alouatta sp.) are obligatory trichromats. In all other platyrrines, only females can be trichromats, while males are always dichromats, as determined by multiple ...
José Augusto Pereira Carneiro Muniz +4 more
doaj +1 more source
SpikeSEE: An Energy-Efficient Dynamic Scenes Processing Framework for Retinal Prostheses [PDF]
arXiv, 2022 Intelligent and low-power retinal prostheses are highly demanded in this era, where wearable and implantable devices are used for numerous healthcare applications. In this paper, we propose an energy-efficient dynamic scenes processing framework (SpikeSEE) that combines a spike representation encoding technique and a bio-inspired spiking recurrent ...
arxiv
Synapse Loss and Dendrite Remodeling in a Mouse Model of Glaucoma. [PDF]
PLoS ONE, 2015 It has been hypothesized that synaptic pruning precedes retinal ganglion cell degeneration in glaucoma, causing early dysfunction to retinal ganglion cells.
Ryan H Berry +4 more
doaj +1 more source
Scientific Reports, 2019 Muscarinic acetylcholine receptors have been implicated as potential neuroprotective targets for glaucoma. We tested the hypothesis that the lack of a single muscarinic receptor subtype leads to age-dependent neuron reduction in the retinal ganglion cell
Panagiotis Laspas +9 more
doaj +1 more source