Results 41 to 50 of about 107,837 (281)

Stem Cells, Retinal Ganglion Cells and Glaucoma [PDF]

, 2014
Retinal ganglion cells (RGCs) represent an essential neuronal cell type for vision. These cells receive inputs from light-sensing photoreceptors via retinal interneurons and then relay these signals to the brain for further processing. RGC diseases that result in cell death, e.g.
Valentin M, Sluch, Donald J, Zack
openaire   +2 more sources

Damage and repair in retinal degenerative diseases: Molecular basis through clinical translation

Neural Regeneration Research
Retinal ganglion cells are the bridging neurons between the eye and the central nervous system, transmitting visual signals to the brain. The injury and loss of retinal ganglion cells are the primary pathological changes in several retinal degenerative ...
Ziting Zhang, Junfeng Ma, Wahid Shah, Xin Quan, Tao Ding, Yuan Gao   +5 more
doaj   +1 more source

Suppressed retinal degeneration in aged wild type and APPswe/PS1ΔE9 mice by bone marrow transplantation. [PDF]

PLoS ONE, 2013
Alzheimer's disease (AD) is an age-related condition characterized by accumulation of neurotoxic amyloid β peptides (Aβ) in brain and retina. Because bone marrow transplantation (BMT) results in decreased cerebral Aβ in experimental AD, we hypothesized ...
Yue Yang, Christine Shiao, Jake Frederick Hemingway, Nikolas L Jorstad, Bryan Richard Shalloway, Rubens Chang, C Dirk Keene   +6 more
doaj   +1 more source

Vertical Macular Asymmetry Measures Derived From SD-OCT for Detection of Early Glaucoma. [PDF]

, 2017
PurposeTo test the hypothesis that vertical asymmetry in macular ganglion cell/inner plexiform layer (GCIPL) thickness can improve detection of early glaucoma.MethodsSixty-nine normal eyes and 101 glaucoma eyes had macular imaging with spectral-domain ...
Afifi, Abdelmonem A, Caprioli, Joseph, Giaconi, JoAnn, Lee, Ji Woong, Morales, Esteban, Nouri-Mahdavi, Kouros, Sharifipour, Farideh, Yu, Fei   +7 more
core   +1 more source

Encoding surprise by retinal ganglion cells

PLOS Computational Biology, 2022
The efficient coding hypothesis posits that early sensory neurons transmit maximal information about sensory stimuli, given internal constraints. A central prediction of this theory is that neurons should preferentially encode stimuli that are most surprising.
Danica Despotović, Corentin Joffrois, Olivier Marre, Matthew Chalk   +3 more
openaire   +3 more sources

Activated retinal glia mediated axon regeneration in experimental glaucoma

Neurobiology of Disease, 2012
Glaucoma, a leading cause of blindness, is a neurodegenerative disease characterized by progressive loss of retinal ganglion cell axons in the optic nerve and their cell bodies in the retina.
Barbara Lorber, Alessandra Guidi, James W. Fawcett, Keith R. Martin   +3 more
doaj   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

On the complex dynamics of intracellular ganglion cell light responses in the cat retina [PDF]

, 1994
We recorded intracellular responses from cat retinal ganglion cells to sinusoidal flickering lights and compared the response dynamics to a theoretical model based on coupled nonlinear oscillators.
Lankheet, M. J. M., Przybyszewski, A. W., Van de Grind, W. A.   +2 more
core   +1 more source

Otx2 stimulates adult retinal ganglion cell regeneration [PDF]

Neural Regeneration Research, 2020
AbstractRetinal ganglion cell axons provide the only link between the light sensitive and photon transducing neural retina and visual centers of the brain. Retinal ganglion cell axon degeneration occurs in a number of blinding diseases and the ability to stimulate axon regeneration from surviving ganglion cells could provide the anatomic substrate for ...
Ibad, Raoul Torero, Quenech’du, Nicole, Prochiantz, Alain, Moya, Kenneth   +3 more
openaire   +3 more sources

Unlocking Photodetection Mode Switching from a Simple Lateral Design

Advanced Functional Materials, EarlyView.
A simple lateral 2D perovskite photodetector capable of switching among transient, continuous, and dual transient/continuous photoresponse modes is achieved by integrating photoconductive effects with capacitive coupling from the SiO2/Si substrate. Such light‐programmable photodetection mode switching enables triple‐channel information transmission and
Zijun (June) Yong, Keng‐Te Lin, Joel van Embden, Taimur Ahmed, Yumeng Du, Dashen Dong, Yiwen Mai, Junlin Lu, Sumeet Walia, Baohua Jia, Tianyi Ma   +10 more
wiley   +1 more source