Results 61 to 70 of about 119,076 (326)

Signal transmission through the dark-adapted retina of the toad (Bufo marinus). Gain, convergence, and signal/noise. [PDF]

, 1990
Responses to light were recorded from rods, horizontal cells, and ganglion cells in dark-adapted toad eyecups. Sensitivity was defined as response amplitude per isomerization per rod for dim flashes covering the excitatory receptive field centers.
Copenhagen, David, Hemilä, S, Reuter, T
core   +2 more sources

Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih, Sara Samadzadeh, Charlotte Bereuter, Seyedamirhosein Motamedi, Claudia Chien, Pablo Villoslada, Hadas Stiebel‐Kalish, Nasrin Asgari, Yang Mao‐Draayer, Marius Ringelstein, Joachim Havla, Marco Aurélio Lana Peixoto, Ho Jin Kim, Jacqueline Palace, Maria Isabel Leite, Srilakshmi M. Sharma, Fereshteh Ashtari, Rahele Kafieh, Lekha Pandit, Orhan Aktas, Philipp Albrecht, Letizia Leocani, Itay Lotan, Sasitorn Siritho, Jérôme de Seze, Romain Marignier, Caroline Froment Tilikete, Denis Bernardi Bichuetti, Ivan Maynart Tavares, Ayse Altintas, Anu Jacob, Saif Huda, Ibis Soto de Castillo, Lawrence J. Cook, Michael R. Yeaman, Axel Petzold, Alexander U. Brandt, Friedemann Paul, Frederike C. Oertel, Hanna G. Zimmermann, with the Guthy Jackson Charitable Foundation—International Clinical Consortium and CROCTINO Collaborators   +40 more
wiley   +1 more source

Tonicity response element binding protein associated with neuronal cell death in the experimental diabetic retinopathy [PDF]

, 2014
AIM: To study the contribution of tonicity response element binding protein (TonEBP) in retinal ganglion cell (RGC) death of diabetic retinopathy (DR). METHODS: Diabetes was induced in C57BL/6 mice by five consecutive intraperitoneal injections of 55 mg/
Choi, Wan-Sung, Chung, Inyoung, Kim, Hwajin, Kim, Seong-Jae, Kwon, H. Moo, Park, Jeongsook, Yoo, Ji-Myong   +6 more
core   +2 more sources

Near‐Infrared Organic Photovoltaic Electrodes for Subretinal Neurostimulation

Advanced Functional Materials, EarlyView.
Organic photovoltaic electrodes based on the D18:Y6 blend enable precise and light‐controlled activation of retinal ganglion cells in a degenerating retina. NIR Light‐driven activation of retinal ganglion cells, tunable stimulation parameters, and biocompatibility with human retinal organoids highlight their potential for next‐generation prosthetics ...
Andrea Corna, Katarina Gugujonovic, Manuela Schiek, Alessandro Bellapianta, Paul Werginz, Amelie Ziller, Markus Clark Scharber, Ahmad Salti, Matthias Bolz, Mihai Irimia‐Vladu, Günther Zeck   +10 more
wiley   +1 more source

Temporal structure in spiking patterns of ganglion cells defines perceptual thresholds in rodents with subretinal prosthesis. [PDF]

, 2018
Subretinal prostheses are designed to restore sight in patients blinded by retinal degeneration using electrical stimulation of the inner retinal neurons.
Goetz, Georges, Ho, Elton, Kamins, Theodore, Laszlo, Florian, Lei, Xin, Lorach, Henri, Mariani, Jean-Charles, Palanker, Daniel, Sher, Alexander   +8 more
core   +3 more sources

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

Advanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter, Caterina Vanelli Coralli, Robert Dzhanaev, Aaron Morgan, Willi Jahnen‐Dechent, Sergio Bertazzo   +5 more
wiley   +1 more source

Nonmulberry Silk Fibroin Doping Boosts Charge Transfer and Charge Injection in Aligned Polypyrrole‐Silk Scaffolds for Low‐Voltage Neurostimulation

Advanced Materials Interfaces, EarlyView.
Conductive silk‐polypyrrole scaffolds couple redox stability with cell‐affinitive peptides present innately in an endogenous silk fibroin, enabling optimized electrical stimulation to drive neurite outgrowth. Findings establish electrochemical‐biological link for biomaterial design rules for smart nerve guidance conduits that can provide low voltage ...
Rajiv Borah, Joseph Christakiran Moses, Jnanendra Upadhyay, Jitu Mani Das, Michael G. Monaghan, Biman B. Mandal   +5 more
wiley   +1 more source

Single-cell RNA sequencing analysis of the retina under acute high intraocular pressure

Neural Regeneration Research
High intraocular pressure causes retinal ganglion cell injury in primary and secondary glaucoma diseases, yet the molecular landscape characteristics of retinal cells under high intraocular pressure remain unknown. Rat models of acute hypertension ocular
Shaojun Wang, Siti Tong, Xin Jin, Na Li, Pingxiu Dang, Yang Sui, Ying Liu, Dajiang Wang   +7 more
doaj   +1 more source

Ganglion cell and displaced amacrine cell density distribution in the retina of the howler monkey (Alouatta caraya). [PDF]

PLoS ONE, 2014
Unlike all other New World (platyrrine) monkeys, both male and female howler monkeys (Alouatta sp.) are obligatory trichromats. In all other platyrrines, only females can be trichromats, while males are always dichromats, as determined by multiple ...
José Augusto Pereira Carneiro Muniz, Luana Modesto de Athaide, Bruno Duarte Gomes, Barbara L Finlay, Luiz Carlos de Lima Silveira   +4 more
doaj   +1 more source

σ2R/TMEM97 in Retinal Ganglion Cell Degeneration

Scientific Reports, 2022
Abstract The sigma 2 receptor (σ2R) was recently identified as an ER (endoplasmic reticulum) membrane protein known as transmembrane protein 97 (TMEM97). Studies have shown that compounds that bind to σ2R/TMEM97 are neuroprotective, suggesting that σ2R/TMEM97 is involved in pathways leading to neurodegeneration.
Hua Wang, Zhiyou Peng, Yiwen Li, James J. Sahn, Timothy R. Hodges, Tsung-Han Chou, Qiong Liu, Xuezhi Zhou, Shuliang Jiao, Vittorio Porciatti, Daniel J. Liebl, Stephen F. Martin, Rong Wen   +12 more
openaire   +3 more sources