Results 61 to 70 of about 103,275 (189)
Scientific Reports, 2017 A photoreceptor cell line, 661W, derived from a mouse retinal tumor that expresses several markers of cone photoreceptor cells has been described earlier. However, these cells can be differentiated into neuronal cells. Here, we report that this cell line
Zuberwasim Sayyad +3 more
doaj +1 more source
Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neurons
Molecular Neurodegeneration, 2011 Background Brimonidine is a common drug for lowering ocular pressure and may directly protect retinal ganglion cells in glaucoma. The disease involves early loss of retinal ganglion cell transport to brain targets followed by axonal and somatic ...
Crish Samuel D +4 more
doaj +1 more source
Retinal ganglion cells: dying to survive
The International Journal of Developmental Biology, 2006 This review examines the maturation of the retinal ganglion cell (RGC) population within the nascent retina. Apoptosis, a form of programmed cell death prevalent throughout the developing central nervous system (CNS), is evident in the growth of RGCs within the ganglion cell layer.
Marc B Guerin +3 more
openaire +4 more sources
Sperry versus Hebb: Topographic mapping in Isl2/EphA3 mutant mice [PDF]
arXiv, 2008 In wild-type mice axons of retinal ganglion cells establish topographically precise projection to the superior colliculus of the midbrain. This implies that axons of neighboring retinal ganglion cells project to the proximal locations in the target. The precision of topographic projection is a result of combined effects of molecular labels, such as Eph
arxiv
A Novel In Vitro Sensing Configuration for Retinal Physiology Analysis of a Sub-Retinal Prosthesis
Sensors, 2012 This paper presents a novel sensing configuration for retinal physiology analysis, using two microelectrode arrays (MEAs). In order to investigate an optimized stimulation protocol for a sub-retinal prosthesis, retinal photoreceptor cells are stimulated,
Kyung Hwan Kim +6 more
doaj +1 more source
Metabolically Efficient Codes in The Retina [PDF]
arXiv, 2001 We tested the hypothesis that the neural code of retinal ganglion cells is optimized to transmit visual information at minimal metabolic cost. Under a broad ensemble of light patterns, ganglion cell spike trains consisted of sparse, precise bursts of spikes. These bursts were viewed as independent neural symbols.
arxiv
Differential response of the retinal neural code with respect to the sparseness of natural images [PDF]
, 2016 Natural images follow statistics inherited by the structure of our physical (visual) environment. In particular, a prominent facet of this structure is that images can be described by a relatively sparse number of features. To investigate the role of this sparseness in the efficiency of the neural code, we designed a new class of random textured ...
arxiv +1 more source
Neuroprotective effects of VCP modulators in mouse models of glaucoma
Heliyon, 2016 Glaucoma is a major cause of adult blindness due to gradual death of retinal ganglion cells. Currently, no therapeutics are available for the protection of these cells from the cell death. We have recently succeeded in synthesizing novel compounds, KUSs (
Noriko Nakano +10 more
doaj +1 more source
Rat retinal ganglion cells in culture
Experimental Eye Research, 1991 A stable cell culture system of identified retinal ganglion cells would facilitate the investigation of cellular mechanisms of damage from glaucoma and other disorders. We have developed a reliable technique to culture retinal ganglion cells on a glial cells monolayer which extends viability and promotes extensive neurite outgrowth. Dissociated retinal
Naoto Takahashi +2 more
openaire +3 more sources
Brazilian Journal of Medical and Biological Research, 2005 Exclusion of the transcription factor Max from the nucleus of retinal ganglion cells is an early, caspase-independent event of programmed cell death following damage to the optic axons.
H. Petrs-Silva +4 more
doaj +1 more source