Results 81 to 90 of about 107,837 (281)

The M1 muscarinic acetylcholine receptor subtype is important for retinal neuron survival in aging mice

open access: yesScientific Reports, 2019
Muscarinic acetylcholine receptors have been implicated as potential neuroprotective targets for glaucoma. We tested the hypothesis that the lack of a single muscarinic receptor subtype leads to age-dependent neuron reduction in the retinal ganglion cell
Panagiotis Laspas   +9 more
doaj   +1 more source

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

open access: yesAdvanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita   +4 more
wiley   +1 more source

Spatially and Temporally Regulated NRF2 Gene Therapy Using Mcp-1 Promoter in Retinal Ganglion Cell Injury

open access: yesMolecular Therapy: Methods & Clinical Development, 2017
Retinal ganglion cell degeneration triggered by axonal injury is believed to underlie many ocular diseases, including glaucoma and optic neuritis. In these diseases, retinal ganglion cells are affected unevenly, both spatially and temporally, such that ...
Kosuke Fujita   +3 more
doaj   +1 more source

Synapse Loss and Dendrite Remodeling in a Mouse Model of Glaucoma. [PDF]

open access: yesPLoS ONE, 2015
It has been hypothesized that synaptic pruning precedes retinal ganglion cell degeneration in glaucoma, causing early dysfunction to retinal ganglion cells.
Ryan H Berry   +4 more
doaj   +1 more source

Retina‐Inspired Bi‐Based Terahertz Photonic Neuromorphic Devices

open access: yesAdvanced Science, EarlyView.
Combined with effective band alignment and substrate engineering, bismuth materials are introduced to form terahertz photonic bio‐inspired devices with picosecond short‐term plasticity to enable multi‐scene visual perception. Thus obtained hardware through the terahertz optical neural network (THz‐ONN) demonstrates high recognition accuracy, providing ...
Pujing Zhang   +14 more
wiley   +1 more source

Effects of tACS-Like Electrical Stimulation on Correlated Firing of Retinal Ganglion Cells: Part III

open access: yesEye and Brain, 2022
Franklin R Amthor, Christianne E Strang Department of Psychology, The University of Alabama at Birmingham, Birmingham, AL, 35294, USACorrespondence: Franklin R AmthorDepartment of Psychology, The University of Alabama at Birmingham, 1300 University Blvd,
Amthor FR, Strang CE
doaj  

Monitoring retinal changes with optical coherence tomography predicts neuronal loss in experimental autoimmune encephalomyelitis. [PDF]

open access: yes, 2019
BACKGROUND:Retinal optical coherence tomography (OCT) is a clinical and research tool in multiple sclerosis, where it has shown significant retinal nerve fiber (RNFL) and ganglion cell (RGC) layer thinning, while postmortem studies have reported RGC loss.
Aktas, Orhan   +18 more
core   +1 more source

Rat retinal ganglion cells in culture

open access: yesExperimental Eye Research, 1991
A stable cell culture system of identified retinal ganglion cells would facilitate the investigation of cellular mechanisms of damage from glaucoma and other disorders. We have developed a reliable technique to culture retinal ganglion cells on a glial cells monolayer which extends viability and promotes extensive neurite outgrowth. Dissociated retinal
N, Takahashi, D, Cummins, J, Caprioli
openaire   +2 more sources

Molecular Biology of Retinal Ganglion Cells [PDF]

open access: yesCells, 2020
The main goal of this thematic issue was to bring both original research papers and reviews together to provide an insight into the rather broad topic of molecular biology of retinal ganglion cells (RGCs) [...]
openaire   +3 more sources

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

open access: yesAdvanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu   +4 more
wiley   +1 more source

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